journal article·2012-03Open access

Initial Attatchment of rMSC and MG‐63 Cells on Patterned Bioglass® Substrates

Rainer Detsch, Olivier Guillon, Lothar Wondraczek, Aldo R. Boccaccini

Advanced Engineering Materials· Volume 14· Issue 3

Abstract

Abstract A soft lithography technique was used to introduce surface patterns on the surface of sintered bioactive glass substrates. Osteoblast‐like MG‐63 cells and rat mesenchymal stem cells (rMSC) seeded on micropatterned bioactive glass surfaces showed different behavior with rMSC exhibiting a better initial attachment than MG‐63 cells. Both cytoskeleton formation and cell spreading of rMSC were supported by the bioactive surfaces. In addition, the structured surfaces seemed to guide MG‐63 cells to a larger extent than rMSC. The in vitro results are important considering the continuous development of bone tissue scaffolds based on silicate bioactive glasses.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Dental materials and restorations · Dental Implant Techniques and Outcomes

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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