journal article·2026-02

A wash-free polarity fluorescent probes targeting lipid droplets for the diagnosis of tumor and non-alcoholic fatty liver disease

Sichen Zhang, Jie Wang, Zhiyu Wang, Jiale Li, Qi Su, Chunfei Wang, Lei Hu, Hui Wang

Dyes and Pigments· Volume 245
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Abstract

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References (46)

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1. Fluorescent probes-illuminate the interplay network between lipid droplets and other organelles10.1016/j.ccr.2024.215792 ↗
2. Recent advances in fluorescent probes for lipid droplets10.3390/ma11091768 ↗
3. A multi-photon fluorescent probe based on quinoline groups for the highly selective and sensitive detection of lipid droplets10.1039/D0AN01847C ↗
4. Construction and evaluation of near-infrared fluorescent probes for imaging lipid droplet and lysosomal viscosity10.1016/j.saa.2024.124356 ↗
5. Specific polysiloxane-based fluorescent probe for imaging ONOO- in lipid droplet10.1016/j.microc.2023.109695 ↗
6. BODIPY 493 acts as a bright buffering fluorogenic probe for super-resolution imaging of lipid droplet dynamics10.1016/j.cclet.2022.03.120 ↗
7. Recent advances in fluorescent probes for fatty liver imaging by detecting lipid droplets10.1039/D4TB01741B ↗
8. Synthesis of fluorescent dyes based on the electron-withdrawing core of malononitrile and construction of viscosity-sensitive AIE probe with large stokes shift for lipid droplets imaging10.1016/j.dyepig.2024.112528 ↗
9. An ultrasensitive lipid droplet-targeted NIR emission fluorescent probe for polarity detection and its application in liver disease diagnosis10.1039/D2TB01145J ↗
10. Modification of an AIE fluorescent probe for monitoring the polarity of lipid droplets based on a series of synthesized aryl naphthalizes10.1002/chem.202401763 ↗
11. One-step assembly of pd-keggin-polyoxometalates for catalytic benzothiadiazole generation and derived cell-imaging probe application10.1016/j.cclet.2022.07.035 ↗
12. Highly efficient red/NIR-emissive fluorescent probe with polarity-sensitive character for visualizing cellular lipid droplets and determining their polarity10.1021/acs.analchem.2c02077 ↗
13. Lipid droplet-specific fluorescent probe for in vivo visualization of polarity in fatty liver, inflammation, and cancer models10.1021/acs.analchem.1c01125 ↗
14. Efficiently emissive, strongly solvatochromic and lipid droplet-specific, fluorescent probes for mapping polarity in vitro10.1016/j.dyepig.2021.109838 ↗
15. A fluorescent probe for lipid droplet polarity imaging with low viscosity crosstalk10.1039/D3AN00551H ↗
16. Three polarity-sensitive fluorescence probe possessing AIE activity and its application on lipid droplets imaging10.1016/j.dyepig.2023.111082 ↗
17. Fluorescent probes for disease diagnosis10.1021/acs.chemrev.3c00776 ↗
18. Design, synthesis, application and research progress of fluorescent probes10.1007/s10895-023-03344-7 ↗
19. Advances in the development of fluorescence probes for cell plasma membrane imaging10.1016/j.trac.2020.116092 ↗
20. Simultaneous monitoring of polarity changes of lipid droplets and lysosomes with two-photon fluorescent probes10.1016/j.aca.2020.08.033 ↗
21. A fluorescence probe for imaging lipid droplet and visualization of diabetes-related polarity variations10.1016/j.aca.2024.342748 ↗
22. Recent advances in 1,8-naphthalimide-based responsive small-molecule fluorescent probes with a modified C4 position for the detection of biomolecules10.1016/j.trac.2023.117242 ↗
23. Recent advances and perspectives in reaction-based fluorescent probes for imaging peroxynitrite in biological systems10.1016/j.ccr.2022.214848 ↗
24. Stable super-resolution imaging of lipid droplet dynamics through a buffer strategy with a hydrogen-bond sensitive fluorogenic probe10.1002/anie.202111052 ↗
25. Turn-on fluorescent probe for lipid droplet specific imaging of fatty liver and atherosclerosis10.1039/D1TB00335F ↗
26. Two-photon fluorescent probes for detecting the viscosity of lipid droplets and its application in living cells10.1039/D0RA09683K ↗
27. Recent development of small-molecule fluorescent probes based on phenothiazine and its derivates10.1016/j.jphotobiol.2022.112528 ↗
28. Fluorescent rotary switches: Four- vs three-substituted phthalimide boron difluoride schiff base complexes10.1021/acs.joc.3c02056 ↗
29. Triphenylamine-based AIE fluorescence probe for lipid droplets imaging in living cells10.1016/j.jphotochem.2024.116248 ↗
30. A fluorescent probe for bioimaging of GSH in cancer cells10.1016/j.saa.2023.123457 ↗
31. Heavy atom quenched coumarin probes for sensitive and selective detection of biothiols in living cells10.1039/C5AN00549C ↗
32. Ladder-type dye with large transition dipole moment for solvatochromism and microphase visualization10.1021/acsami.9b07677 ↗
33. Interface-targeting strategy enables two-photon fluorescent lipid droplet probes for high-fidelity imaging of turbid tissues and detecting fatty liver10.1021/acsami.8b00278 ↗
34. Synthesis of a red-emitting polarity-sensitive fluorescent probe based on ICT and visualization for lipid droplet dynamic processes10.1021/acsbiomaterials.3c00409 ↗
35. Isophorone-based AIEgens fluorescent probe with red emission for targeting lipid droplets and identifying non-alcoholic fatty liver disease10.1016/j.saa.2023.123588 ↗
36. Near-infrared lipid droplets polarity fluorescent probe for early diagnosis of nonalcoholic fatty liver disease10.1016/j.saa.2024.124479 ↗
37. Rational design of an AIEgen for imaging lipid droplets polarity change during ferroptosis10.1016/j.saa.2024.124701 ↗
38. A triphenylamine-based fluorescent probe with large stokes shift for wash-free imaging of lipid droplets and diagnosis of fatty liver10.1039/D4NJ01299B ↗
39. Caveolin-1 attenuates acetaminophen aggravated lipid accumulation in alcoholic fatty liver by activating mitophagy via the Pink-1/Parkin pathway10.1016/j.ejphar.2021.174324 ↗
40. Lipid droplet-specific NIR fluorescent probe with large stokes shift for assessing the effect of chronic drugs on drug-induced liver injury10.1016/j.snb.2024.137089 ↗
41. Unveiling dynamic alterations of lipid droplet polarity during NAFLD-triggered lipophagy utilizing a far-red fluorescent probe with large stokes shift10.1016/j.snb.2024.136509 ↗
42. Imaging changes in the polarity of lipid droplets during NAFLD-induced ferroptosis via a red-emitting fluorescent probe with a large stokes shift10.1016/j.bios.2023.115289 ↗
43. A polarity-sensitive ratiometric fluorescence probe for monitoring changes in lipid droplets and nucleus during ferroptosis10.1002/anie.202104163 ↗
44. Managing ferroptosis-related diseases with indirect dietary modulators of ferroptosis10.1016/j.jnutbio.2023.109427 ↗
45. Near-infrared polarity fluorescent probe for wash-free imaging lipid droplets and the application in the diagnosis of non-alcoholic fatty liver tissue10.1016/j.microc.2024.111236 ↗
46. A cisplatin-selective fluorescent probe for real-time monitoring of mitochondrial platinum accumulation in living cells10.1002/anie.202010951 ↗