Probing the Near-Atomic Scale Structure of Hard Biological Materials with Atom Probe Tomography: A Review

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7. Observation of hydrogen trapping at dislocations, grain boundaries, and precipitates

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9. Cu2ZnSnS4 solar cells with over 10% power conversion efficiency enabled by heterojunction heat treatment10.1038/s41560-018-0206-0 ↗

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13. Atomic-scale characterization of planar selective-area-grown InAs/InGaAs nanowires10.1021/acsami.2c09594 ↗

14. Atom probe tomography of encapsulated hydroxyapatite nanoparticles

15. Revealing the distribution of the atoms within individual bimetallic catalyst nanoparticles10.1002/anie.201405043 ↗

16. Ag-segregation to dislocations in PbTe-based thermoelectric materials10.1021/acsami.7b17142 ↗

17. Developing atom probe tomography of phyllosilicates in preparation for extra-terrestrial sample return10.1111/ggr.12382 ↗

18. Atom probe tomography: development and application to the geosciences10.1111/ggr.12313 ↗

19. Shock melt in the cold Bokkeveld CM2 carbonaceous chondrite and the response of C-complex asteroids to hypervelocity impacts

20. A nanoscale investigation of carlin-type gold deposits: an atom-scale elemental and isotopic perspective10.5382/econgeo.4676 ↗

21. Atomic scale chemical tomography of human bone10.1038/srep39958 ↗

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23. Discovering an unknown territory using atom probe tomography: elemental exchange at the bioceramic scaffold/bone tissue interface10.1016/j.actbio.2023.02.039 ↗

24. Atom probe crystallography10.1016/S1369-7021(12)70164-5 ↗

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28. Deciphering chemical order/disorder and material properties at the single-atom level10.1038/nature21042 ↗

29. Advancing atom probe tomography capabilities to understand bone microstructures at near-atomic scale10.1016/j.actbio.2025.03.051 ↗

30. Nanoscale pathways for human tooth decay – central planar defect, organic-rich precipitate and high-angle grain boundary10.1016/j.biomaterials.2019.119748 ↗

31. Atomic-scale compositional mapping reveals Mg-rich amorphous calcium phosphate in human dental enamel10.1126/sciadv.1601145 ↗

32. The bone-implant interface of dental implants in humans on the atomic scale10.1016/j.actbio.2016.11.044 ↗

33. Chemical gradients in human enamel crystallites10.1038/s41586-020-2433-3 ↗

34. Multi-scale characterization of developmental defects of enamel and their clinical significance for diagnosis and treatment10.1016/j.actbio.2023.08.011 ↗

35. Developing atom probe tomography to characterize sr-loaded bioactive glass for bone scaffolding10.1017/S1431927621012976 ↗

36. Advanced characterization on nanostructure in steels

37. Characterising the performance of an ultrawide field-of-view 3D atom probe10.1016/j.ultramic.2023.113826 ↗

38. Time-of-flight mass spectrometry and composition measurements

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40. Practical determination of spatial resolution in atom probe tomography10.1017/S1431927609098717 ↗

41. New frontiers in atom probe tomography: a review of research enabled by cryo and/or vacuum transfer systems

42. Correlative UHV-Cryo transfer suite: connecting atom probe, SEM-FIB, transmission electron microscopy via an environmentally-controlled glovebox10.1017/S1431927619013205 ↗

43. The laplace project: an integrated suite for preparing and transferring atom probe samples under cryogenic and UHV conditions10.1371/journal.pone.0209211 ↗

44. Pulsed-laser atom-probe field-ion microscopy10.1063/1.327686 ↗

45. A modular atom probe concept: design, operational aspects, and performance of an integrated APT-FIB/SEM solution10.1017/S1431927621013982 ↗

46. Atom probe tomography10.1063/1.2709758 ↗

47. Depth and lateral resolution of laser-assisted atom probe microscopy of silicon revealed by isotopic heterostructures10.1063/1.3544496 ↗

48. Field-ion specimen preparation using focused ion-beam milling10.1016/S0304-3991(99)00055-8 ↗

49. Miller · 2014

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52. In situ site-specific specimen preparation for atom probe tomography10.1016/j.ultramic.2006.06.008 ↗

53. Surface damage induced by FIB milling and imaging of biological samples is controllable10.1002/jemt.20494 ↗

54. The impact of focused ion beam induced damage on scanning spreading resistance microscopymeasurements10.1038/s41598-020-71826-w ↗

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56. On the fabrication of atom probe tomography specimens of Al alloys at room temperature using focused ion beam milling with liquid ga ion source10.1002/jemt.24151 ↗

57. Large volume serial section tomography by Xe plasma FIB dual beam microscopy10.1016/j.ultramic.2015.11.001 ↗

58. Atom probe tomography of apatites and bone-type mineralized tissues10.1021/nn3049957 ↗

59. Atomically resolved tissue integration10.1021/nl501564f ↗

60. Exploring the accuracy of isotopic analyses in atom probe mass spectrometry10.1016/j.ultramic.2020.113018 ↗

61. Behavior of molecules and molecular ions near a field emitter10.1088/1367-2630/18/3/033031 ↗

62. Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel

63. Amorphous intergranular phases control the properties of rodent tooth enamel10.1126/science.1258950 ↗

64. Characterization of tooth withamelogenesis imperfecta (AI) by atom probe tomography10.1557/s43580-024-00914-0 ↗

65. Secondary ion mass spectrometry and X-ray microanalysis of hypomineralized enamel in human permanent first molars10.1016/S0003-9969(00)00113-8 ↗

66. Nanoscale chemical tomography of buried organic-inorganic interfaces in the chiton tooth10.1038/nature09686 ↗

67. Overcoming challenges associated with the analysis of nacre by atom probe tomography10.1111/ggr.12279 ↗

68. Growth dynamics and amorphous-to-crystalline phase transformation in natural nacre10.1038/s41467-023-37814-0 ↗

69. Alberts · 2002

70. Atom probe tomography for 3D structural and chemical analysis of individual proteins

71. A near atomic-scale view at the composition of amyloid-beta fibrils by atom probe tomography10.1038/s41598-018-36110-y ↗

72. Atom probe tomographic mapping directly reveals the atomic distribution of phosphorus in resin embedded ferritin10.1038/srep22321 ↗

73. Three-dimensional chemical mapping of a single protein in the hydrated state with atom probe tomography10.1021/acs.analchem.9b05668 ↗

74. Resolving protein-mineral interfacial interactions during in vitro mineralization by atom probe tomography

75. Chemical mapping of mammalian cells by atom probe tomography10.1016/j.jsb.2011.12.016 ↗

76. Near-atomic three-dimensional mapping for site-specific chemistry of “superbugs.10.1021/acs.nanolett.6b03409 ↗

77. Enabling near-atomic-scale analysis of frozen water10.1126/sciadv.abd6324 ↗

78. Status and direction of atom probe analysis of frozen liquids10.1017/S1431927621013994 ↗

79. Field evaporation and atom probe tomography of pure water tips10.1038/s41598-020-77130-x ↗

80. Methods of preparing nanoscale vitreous ice needles for high-resolution cryogenic characterization10.1021/acs.nanolett.2c01495 ↗

81. Atom probe tomography reveals nano-scale organic remaining in conodont10.46770/AS.2024.026 ↗

82. Biogeochemical fingerprinting of magnetotactic bacterial magnetite10.1073/pnas.2203758119 ↗

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84. Atomic-scale age resolution of planetary events10.1038/ncomms15597 ↗

85. A versatile and reproducible cryo-sample preparation methodology for atom probe studies10.1093/micmic/ozad120 ↗

86. Nanometer-scale chemistry of a calcite biomineralization template: implications for skeletal composition and nucleation10.1073/pnas.1522864113 ↗

87. Advances in pulsed-laser atom probe: instrument and specimen design for optimum performance10.1017/S1431927607070869 ↗

88. Optimization of parameters for atom probe tomography analysis of-tricalcium phosphates optimization of parameters for atom probe tomography analysis of β-tricalcium phosphates

89. Trajectory overlaps and local magnification in three-dimensional atom probe10.1063/1.126545 ↗