An Amperometric Sensor for Low Level Detection of Antidepressant Drug Carbamazepine Based on Graphene Oxide-g-C₃N₄Composite Film Modified Electrode

Present strategy reports a simple electrochemical sensor for highly sensitive, selective detection of carbamazepine based on the graphene oxide and graphitic carbon nitride composite film modified electrode. The GO/g-C 3 N 4 composite film exhibit incredible electrocatalytic activity in terms of minimized over potential (0.1 V) associated with enhanced anodic current with 4 fold higher than that of control electrode. In addition, the developed sensor yields a very lower detection limit (10.5 nM) with good sensitivity (1.727 μA μM −1 cm −2 ). Furthermore, the developed assay was employed in the determination of CBZ in human urine samples and pharmaceutical samples. Analytical results are reliable, suggested that the proposed sensor can be used for the determination of CBZ in biological and pharmaceutical samples.