journal article·2017Open access

Electrochemical Sensor Based upon Ruthenium Doped TiO2Nanoparticles for the Determination of Flufenamic Acid

Nagaraj P. Shetti, Deepti S. Nayak, Shweta J. Malode, Raviraj M. Kulkarni

Abstract

In the current research, ruthenium stood a conspicuous dopant for TiO 2 nanoparticles, to enhance its catalytic activity. The characterization of synthesized nanoparticles was accomplished by utilizing XRD, SEM, EDX and TEM analysis. The sensing surface morphology was studied by AFM analysis. Further, we established the electrochemical behavior and detection of flufenamic acid (FFA) by utilizing ruthenium doped TiO 2 nanoparticles modified carbon paste electrode (Ru-TiO 2 /CPE) at pH 6.0 by employing different voltammetric techniques. Modification enhances the electro-oxidation of flufenamic acid with increased current intensity. The influence of parameters like scan rate, pH, accumulation time, amount of the modifier and concentration on the peak current of the drug were studied. The effect of FFA concentration variation was studied using square wave voltammetric (SWV) technique and got lowest detection limit compared to reported techniques. The fabricated sensor was employed for the determination of flufenamic acid in biological samples.
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Research context

OpenAlex topics: Electrochemical sensors and biosensors · Electrochemical Analysis and Applications · Analytical Chemistry and Sensors

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References (55)

Show source-provided references
1. Martindale , in: Reynolds J. E. F. (Ed.), The Extra Pharmacopoeia, 31st Edition, The Pharmaceutical Press, London, 1996.
2. Insel P. A. , in: Gilman A. G. Rall T. W. Nies A. S. Goodman P. Taylor Gilman's (Eds.), The Pharmacological Basis of Therapeutics, 8th Edition, McGraw-Hill, New York, 1990 (Chapter 26).
3. 10.1039/an987120139910.1039/an9871201399 ↗
4. 10.1080/0003271900805244410.1080/00032719008052444 ↗
5. 10.1016/S0731-7085(99)00217-410.1016/S0731-7085(99)00217-4 ↗
6. 10.1021/ie049745u10.1021/ie049745u ↗
7. 10.1016/S0039-9140(98)00086-110.1016/S0039-9140(98)00086-1 ↗
8. 10.1016/S0003-2670(98)00172-X10.1016/S0003-2670(98)00172-X ↗
9. 10.1016/j.ab.2006.11.02010.1016/j.ab.2006.11.020 ↗
10. Bettaieb · Turk. J. Chem. · 2001 · 25 · 165
11. 10.1016/0731-7085(95)01519-Q10.1016/0731-7085(95)01519-Q ↗
12. 10.1016/S0003-2670(00)00855-210.1016/S0003-2670(00)00855-2 ↗
13. 10.1080/1082607920802086810.1080/10826079208020868 ↗
14. 10.1016/S0731-7085(00)00444-110.1016/S0731-7085(00)00444-1 ↗
15. 10.1016/0378-4347(95)00518-810.1016/0378-4347(95)00518-8 ↗
16. 10.1002/rcm.39610.1002/rcm.396 ↗
17. 10.1016/S0378-4347(97)00674-910.1016/S0378-4347(97)00674-9 ↗
18. 10.1016/S0731-7085(00)00283-110.1016/S0731-7085(00)00283-1 ↗
19. 10.1002/elan.20040326210.1002/elan.200403262 ↗
20. 10.1016/j.foodchem.2014.10.07510.1016/j.foodchem.2014.10.075 ↗
21. 10.1039/C5AY03284A10.1039/C5AY03284A ↗
22. 10.1016/j.snb.2016.02.05210.1016/j.snb.2016.02.052 ↗
23. 10.1016/j.bios.2016.07.05310.1016/j.bios.2016.07.053 ↗
24. 10.1007/s00604-015-1713-310.1007/s00604-015-1713-3 ↗
25. 10.1039/C5RA22581G10.1039/C5RA22581G ↗
26. 10.1016/j.snb.2016.02.08210.1016/j.snb.2016.02.082 ↗
27. 10.1007/s11581-015-1629-210.1007/s11581-015-1629-2 ↗
28. 10.1016/j.matchemphys.2015.02.03910.1016/j.matchemphys.2015.02.039 ↗
29. 10.1016/j.msec.2012.11.00810.1016/j.msec.2012.11.008 ↗
30. 10.1039/C4RA06767C10.1039/C4RA06767C ↗
31. 10.1351/pac20007209178710.1351/pac200072091787 ↗
32. 10.1039/b107314a10.1039/b107314a ↗
33. 10.1107/S090904950001712X10.1107/S090904950001712X ↗
34. 10.1021/am500488e10.1021/am500488e ↗
35. 10.1039/c4ra03158j10.1039/c4ra03158j ↗
36. 10.1016/j.jcis.2014.06.02610.1016/j.jcis.2014.06.026 ↗
37. 10.1016/j.watres.2015.04.03810.1016/j.watres.2015.04.038 ↗
38. 10.1039/C6RA10233F10.1039/C6RA10233F ↗
39. 10.1016/j.msec.2016.04.04510.1016/j.msec.2016.04.045 ↗
40. 10.1021/jp908088x10.1021/jp908088x ↗
41. 10.4028/www.scientific.net/AMR.55-57.85310.4028/www.scientific.net/AMR.55-57.853 ↗
42. 10.1186/s40543-016-0092-710.1186/s40543-016-0092-7 ↗
43. 10.1016/j.molcata.2005.07.03810.1016/j.molcata.2005.07.038 ↗
44. 10.1021/jp911349y10.1021/jp911349y ↗
45. 10.1007/s10854-016-5449-610.1007/s10854-016-5449-6 ↗
46. 10.1016/j.colsurfb.2012.04.01010.1016/j.colsurfb.2012.04.010 ↗
47. 10.1016/j.snb.2016.04.09710.1016/j.snb.2016.04.097 ↗
48. 10.1016/j.msec.2016.01.02510.1016/j.msec.2016.01.025 ↗
49. Gosser D. K. , Cyclic Voltammetry: Simulation and Analysis of Reaction Mechanisms, VCH, New York; (1993) 43.
50. 10.1016/j.talanta.2009.06.01910.1016/j.talanta.2009.06.019 ↗
51. Nayak · Asian J. Pharm. Clin. Res. · 2015 · 8 · 125
52. Bard A. J. Faulkner L. R. , Electrochemical Methods Fundamentals and Applications, 2nd ed., Wiley, New York; 2004.
53. 10.1016/j.jelechem.2016.08.02410.1016/j.jelechem.2016.08.024 ↗
54. Krull M. SwartzandI. , Analytical Method Development and Validation, Marcel Dekker, New York, 1997.
55. 10.1007/s11743-016-1854-310.1007/s11743-016-1854-3 ↗