journal article·2025-06

Integrated hydrogel of fucoidan and rhCol III for bioprosthetic heart valves to promote the antithrombosis, anti-inflammatory, and anti-calcification properties

Kaiyang Huang, Cheng Zheng, Xueyu Huang, Bangquan Wei, Lepeng Chen, Gaocan Li, Li Yang, Yunbing Wang

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OpenAlex topics: Aortic Disease and Treatment Approaches · Seaweed-derived Bioactive Compounds · Electrospun Nanofibers in Biomedical Applications

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References (53)

Show source-provided references
1. Epidemiology of valvular heart disease in the adult10.1038/nrcardio.2010.202 ↗
2. Global burden of cardiovascular diseases and risk factors, 1990-2019: update from the GBD 2019 study10.1016/j.jacc.2020.11.010 ↗
3. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American college of cardiology/American heart association task force on practice guidelines10.1016/j.jacc.2014.02.536 ↗
4. Will heart valve tissue engineering change the world?10.1038/ncpcardio0112 ↗
5. Bioprosthetic heart valves: impact of implantation on biomaterials10.5402/2013/728791 ↗
6. Transcatheter heart valve interventions: where are we? Where are we going?10.1093/eurheartj/ehy668 ↗
7. Transcatheter aortic valve replacement10.1161/CIRCULATIONAHA.119.040016 ↗
8. Mechanical or biologic prostheses for aortic-valve and mitral-valve replacement10.1056/NEJMoa1613792 ↗
9. Prevention of thromboembolic events after bioprosthetic aortic valve replacement10.1016/j.jacc.2012.06.014 ↗
10. Thrombosis of prosthetic heart valves: diagnosis and therapeutic considerations10.1136/hrt.2005.071183 ↗
11. Residual bioprosthetic valve immunogenicity: forgotten, not lost
12. Cytotoxicity of glutaraldehyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosis10.1002/jbm.10145 ↗
13. Immune response in patients receiving a bioprosthetic heart valve: lack of response with decellularized valves10.1089/ten.tea.2011.0046 ↗
14. Double bond crosslinked and phosphocholinated biological heart valve with robust antithrombogenicity, durability and anticalcification property
15. Development of transcatheter tissue-engineered heart valves with dual crosslinking and nitric oxide releasing decellularized matrix composites for in-situ regeneration
16. Advanced electrospun hydrogel fibers for wound healing
17. Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications10.1016/j.actbio.2013.07.031 ↗
18. Therapeutic effects of fucoidan: a review on recent studies10.3390/md17090487 ↗
19. Fucoidans as a potential nutraceutical in combating atherosclerotic cardiovascular diseases10.26717/BJSTR.2019.21.003616 ↗
20. Pilot clinical study to evaluate the anticoagulant activity of fucoidan. Blood coagulation & fibrinolysis
21. Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from Ecklonia cava10.1016/j.carbpol.2012.03.056 ↗
22. Mechanism study of endothelial protection and inhibits platelet activation of low molecular weight fucoidan from Laminaria japonica10.1007/s11802-016-3016-7 ↗
23. Clinical applications of fucoidan in translational medicine for adjuvant cancer therapy10.1186/s40169-019-0234-9 ↗
24. A tailored extracellular matrix (ECM) - mimetic coating for cardiovascular stents by stepwise assembly of hyaluronic acid and recombinant human type III collagen10.1016/j.biomaterials.2021.121055 ↗
25. An injectable ECM-like hydrogel with bioactive peptides and RepSox nanoparticles for myocardial infarction treatment10.1016/j.cej.2023.145878 ↗
26. A drug-free cardiovascular stent functionalized with tailored collagen supports in-situ healing of vascular tissues10.1038/s41467-024-44902-2 ↗
27. A strategy for mechanically integrating robust hydrogel-tissue hybrid to promote the anti-calcification and endothelialization of bioprosthetic heart valve10.1093/rb/rbae003 ↗
28. Development of innovative biomaterials and devices for the treatment of cardiovascular diseases
29. Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis properties10.1016/j.biomaterials.2022.121849 ↗
30. A strategy of functional crosslinking acellular matrix in blood-contacting implantable devices with recombinant humanized collagen type III (rhCOLIII)10.1016/j.compositesb.2022.109667 ↗
31. Biaxial mechanical response of bioprosthetic heart valve biomaterials to high in-plane shear10.1115/1.1572518 ↗
32. A comparative study between porcine peritoneum and pericardium as cardiovascular material10.1089/ten.tec.2022.0028 ↗
33. Visible light-induced cross-linking of porcine pericardium for the improvement of endothelialization, anti-tearing, and anticalcification properties10.1002/jbm.a.37263 ↗
34. The collagen of heart valve10.1016/0005-2795(77)90247-1 ↗
35. Collagen cross linking and fibril alignment in pericardium10.1039/C4RA10658J ↗
36. Bio-inspired robust, superhydrophilic and superlubric artificial vascular endothelium coating for anti-thromboinflammation on blood-contacting devices10.1016/j.compositesb.2023.110670 ↗
37. Superhydrophilic versus normal polydopamine coating: a superior and robust platform for synergistic antibacterial and antithrombotic properties10.1016/j.cej.2020.126196 ↗
38. Fucoidan-derived functional oligosaccharides: recent developments, preparation, and potential applications10.3390/foods12040878 ↗
39. Transcatheter aortic valve thrombosis: a review of potential mechanisms10.1098/rsif.2021.0599 ↗
40. Transcatheter aortic valve leaflet thrombosis: prevalence, management, and future directions10.1007/s11886-021-01614-z ↗
41. A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds10.1093/glycob/cwm014 ↗
42. Bioresorbable polymeric scaffold in cardiovascular applications10.3390/ijms21103444 ↗
43. Long-term stability and biocompatibility of pericardial bioprosthetic heart valves10.3389/fcvm.2021.728577 ↗
44. Wang Y, Wu H, Zhou Z, Maitz MF, Liu K, Zhang B, et al. A thrombin-triggered self-regulating anticoagulant strategy combined with anti-inflammatory capacity for blood-contacting implants. Sci Adv.8(9):eabm3378.10.1126/sciadv.abm3378 ↗
45. Markers of systemic inflammation in experimental dyslipidemia induced by P-407: modulation with fucoidan from Brown alga fucus evanescens10.1007/s10517-019-04436-w ↗
46. Incidence, risk factors, clinical impact, and management of bioprosthesis structural valve degeneration10.1097/HCO.0000000000000372 ↗
47. Collagen degradation in a murine myocarditis model: relevance of matrix metalloproteinase in association with inflammatory induction10.1016/S0008-6363(02)00546-1 ↗
48. Immunomodulatory and anti-inflammatory effects of fucoidan: a review10.3390/polym12102338 ↗
49. Calcification of bioprosthetic heart valves and its assessment10.1067/mtc.2001.113595 ↗
50. Calcification of tissue heart valve substitutes: progress toward understanding and prevention10.1016/j.athoracsur.2004.06.033 ↗
51. Nonglutaraldehyde crosslinked bioprosthetic heart valves based on 2-isocyanatoethyl methacrylate crosslinked porcine pericardium with improved properties of stability, cytocompatibility and anti-calcification
52. Response of heterograft heart valve biomaterials to moderate cyclic loading10.1002/jbm.a.30031 ↗
53. Impact of glutaraldehyde on calcification of pericardial bioprosthetic heart valve material10.1016/S0003-4975(96)00442-0 ↗