In-vitro degradation behavior of hybrid epoxy-alkyl sol–gel/anodized composite coating on AZ31B Mg alloy
Source abstract
Abstract
Abstract Mg alloys are considered a promising alternative to use as biodegradable implants. However, the main limitations of these alloys are the high susceptibility to hydrogen evolution and corrosion. Consequently, it is necessary to control the corrosion rate through surface treatment techniques. In this regard, a double layer system, based on the first deposition of a MgO coating and the subsequent deposition of an organo-silane sol-gel coating (anodized/SGMI) was proposed to increase the biocompatibility and reduce the corrosion rate of Mg alloy. Sol-gel coatings were prepared using methyltriethoxysilane (MTES), (glycidyloxypropyl) trimethoxysilane (GPTMS), SiO2 nanoparticles, and 1-methyl imidazole (1-MI). 29Si and 13C NMR measurements were performed to investigate the inorganic-organic network formation during the sol-gel synthesis, and to characterize the structure of the cured silane coating. According to the results, the addition of 1-MI mainly promotes the condensation reaction of GPTMS and MTES. After sol-gel deposition, a higher cross-linking coating network was obtained and the degradation of AZ31B Mg alloy in simulated body fluid (SBF) was slowed down. The control of the hydrogen and pH evolution over 450 h suggest that the anodized/SGMI coating system may be suitable for short-term implants applications; particularly for applications that are expected to degrade after 10-12 days such as surgical skin staples. Graphical Abstract
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Magnesium Alloys: Properties and Applications · Corrosion Behavior and Inhibition · Hydrogen Storage and Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (39)
Show source-provided references
1. Ling L, Cai S, Li Q, Sun J, Bao X, Xu G (2022) Recent advances in hydrothermal modification of calcium phosphorus coating on magnesium alloy. J Magnes Alloy 10:62–80. https://doi.org/10.1016/j.jma.2021.05.01410.1016/j.jma.2021.05.014 ↗
2. Adetunla A, Akinlabi E (2019) Influence of reinforcements in friction stir processed magnesium alloys: insight in medical applications. Mater Res Express 6:025406. https://doi.org/10.1088/2053-1591/aaeea810.1088/2053-1591/aaeea8 ↗
3. Ding Y, Wen C, Hodgson P, Li Y (2014) Effects of alloying elements on the corrosion behavior and biocompatibility of biodegradable magnesium alloys: A review. J Mater Chem B 2:1912–1933. https://doi.org/10.1039/c3tb21746a10.1039/c3tb21746a ↗
4. Merlo JL, Detsch R, Ceré S, Boccaccini AR, Ballarre J (2021) Degradable magnesium implants: improving bioactive and antibacterial performance by designed hybrid coatings. J Mater Res 36:443–458. https://doi.org/10.1557/s43578-020-00099-w10.1557/s43578-020-00099-w ↗
5. Ghosh S, More N, Kapusetti G (2022) Surgical staples: Current state-of-the-art and future prospective. Med Nov Technol Devices 16:100166. https://doi.org/10.1016/j.medntd.2022.10016610.1016/j.medntd.2022.100166 ↗
6. Chng CB, Lau DP, Choo JQ, Chui CK (2012) A bioabsorbable microclip for laryngeal microsurgery: Design and evaluation. Acta Biomater 8:2835–2844. https://doi.org/10.1016/j.actbio.2012.03.05110.1016/j.actbio.2012.03.051 ↗
7. Jung O, Porchetta D, Schroeder ML, Klein M, Wegner N, Walther F et al. (2019) In vivo simulation of magnesium degradability using a new fluid dynamic bench testing approach. Int J Mol Sci 20:4859. https://doi.org/10.3390/ijms2019485910.3390/ijms20194859 ↗
8. Bita AI, Semenescu A, Antoniac A, Antoniac I (2016) Hydrogen evolution analyzed on various magnesium alloys. Key Eng Mater 695:152–15610.4028/www.scientific.net/KEM.695.152 ↗
9. Sanchez AHM, Luthringer BJC, Feyerabend F, Willumeit R (2015) Mg and Mg alloys: How comparable are in vitro and in vivo corrosion rates? A review. Acta Biomater 13:16–31. https://doi.org/10.1016/j.actbio.2014.11.04810.1016/j.actbio.2014.11.048 ↗
10. Li Z, Gu X, Lou S, Zheng Y (2008) The development of binary Mg-Ca alloys for use as biodegradable materials within bone. Biomaterials 29:1329–1344. https://doi.org/10.1016/j.biomaterials.2007.12.02110.1016/j.biomaterials.2007.12.021 ↗
11. Zheng YF, Gu XN, Xi YL, Chai DL (2010) In vitro degradation and cytotoxicity of Mg/Ca composites produced by powder metallurgy. Acta Biomater 6:1783–1791. https://doi.org/10.1016/j.actbio.2009.10.00910.1016/j.actbio.2009.10.009 ↗
12. Gu X, Zheng Y, Cheng Y, Zhong S, Xi T (2009) In vitro corrosion and biocompatibility of binary magnesium alloys. Biomaterials 30:484–498. https://doi.org/10.1016/j.biomaterials.2008.10.02110.1016/j.biomaterials.2008.10.021 ↗
13. Zaffora A, di Franco F, Virtù D, Carfì Pavia F, Ghersi G, Virtanen S et al. (2021) Tuning of the Mg Alloy AZ31 Anodizing Process for Biodegradable Implants. ACS Appl Mater Interfaces 13:12866–12876. https://doi.org/10.1021/acsami.0c2293310.1021/acsami.0c22933 ↗
14. Yin ZZ, Qi WC, Zeng RC, Chen XB, Gu CD, Guan SK et al. (2020) Advances in coatings on biodegradable magnesium alloys. J Magnes Alloy 8:42–65. https://doi.org/10.1016/j.jma.2019.09.00810.1016/j.jma.2019.09.008 ↗
15. Banerjee PC, Al-Saadi S, Choudhary L, Harandi SE, Singh R (2019) Magnesium implants: Prospects and challenges. Materials 12:136. https://doi.org/10.3390/ma1201013610.3390/ma12010136 ↗
16. Barati Darband G, Aliofkhazraei M, Hamghalam P, Valizade N (2017) Plasma electrolytic oxidation of magnesium and its alloys: Mechanism, properties and applications. J Magnes Alloy 5:74–132. https://doi.org/10.1016/j.jma.2017.02.00410.1016/j.jma.2017.02.004 ↗
17. Uddin MS, Hall C, Murphy P (2015) Surface treatments for controlling corrosion rate of biodegradable Mg and Mg-based alloy implants. Sci Technol Adv Mater 16(5):053501. https://doi.org/10.1088/1468-6996/16/5/05350110.1088/1468-6996/16/5/053501 ↗
18. White L, Koo Y, Neralla S, Sankar J, Yun Y (2016) Enhanced mechanical properties and increased corrosion resistance of a biodegradable magnesium alloy by plasma electrolytic oxidation (PEO). Mater Sci Eng B 208:39–46. https://doi.org/10.1016/J.MSEB.2016.02.00510.1016/J.MSEB.2016.02.005 ↗
19. Zaffora A, di Franco F, Virtù D, Carfì Pavia F, Ghersi G, Virtanen S et al. (2021) Tuning of the Mg Alloy AZ31 Anodizing Process for Biodegradable Implants. ACS Appl Mater Interfaces 13:12866–12876. https://doi.org/10.1021/ACSAMI.0C2293310.1021/ACSAMI.0C22933 ↗
20. Bordbar-Khiabani A, Yarmand B, Mozafari M (2019) Enhanced corrosion resistance and in-vitro biodegradation of plasma electrolytic oxidation coatings prepared on AZ91 Mg alloy using ZnO nanoparticles-incorporated electrolyte. Surf Coat Technol 360:153–171. https://doi.org/10.1016/J.SURFCOAT.2019.01.00210.1016/J.SURFCOAT.2019.01.002 ↗
21. Gaur S, Singh Raman RK, Khanna AS (2014) In vitro investigation of biodegradable polymeric coating for corrosion resistance of Mg-6Zn-Ca alloy in simulated body fluid Materials Science and Engineering C 42:91–101. https://doi.org/10.1016/j.msec.2014.05.035.10.1016/j.msec.2014.05.035 ↗
22. Ahmadipour M, Mohammadi H, Pang AL, Arjmand M, Ayode Otitoju T U, Okoye P et al. (2022) A Rev: Silic Ceram-Polym composite scaffold bone tissue Eng Int J Polymeric Mater Polymeric Biomater 71(3):180–195. https://doi.org/10.1080/00914037.2020.181701810.1080/00914037.2020.1817018 ↗
23. Ren L, Tsuru K, Hayakawa S, Osaka A (2002) Novel approach to fabricate porous gelatin-siloxane hybrids for bone tissue engineering. Biomaterials 23(24):4765–4773. https://doi.org/10.1016/S0142-9612(02)00226-010.1016/S0142-9612(02)00226-0 ↗
24. Castro Y, Durán A (2019) Control of degradation rate of Mg alloys using silica sol–gel coatings for biodegradable implant materials. J Solgel Sci Technol 90:198–208. https://doi.org/10.1007/s10971-018-4824-610.1007/s10971-018-4824-6 ↗
25. Liu X, Yue Z, Romeo T, Weber J, Scheuermann T, Moulton S et al. (2013) Biofunctionalized anti-corrosive silane coatings for magnesium alloys. Acta Biomater 9:8671–8677. https://doi.org/10.1016/j.actbio.2012.12.02510.1016/j.actbio.2012.12.025 ↗
26. Gu XN, Guo HM, Wang F, Lu Y, Lin WT, Li J et al. (2017) Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy. Mater Lett 193:266–269. https://doi.org/10.1016/J.MATLET.2017.01.13610.1016/J.MATLET.2017.01.136 ↗
27. Toorani M, Aliofkhazraei M (2019) Review of electrochemical properties of hybrid coating systems on Mg with plasma electrolytic oxidation process as pretreatment. Surf Interfaces 14:262–295. https://doi.org/10.1016/j.surfin.2019.01.00410.1016/j.surfin.2019.01.004 ↗
28. Guo X, An M (2010) Experimental study of electrochemical corrosion behaviour of bilayer on AZ31B Mg alloy. Corros Sci 52:4017–4027. https://doi.org/10.1016/J.CORSCI.2010.08.01710.1016/J.CORSCI.2010.08.017 ↗
29. Merino E, Durán A, Ceré S, Castro Y (2022) Hybrid Epoxy-Alkyl Sol-Gel coatings reinforced with SiO2 nanoparticles for corrosion protection of anodized AZ31B Mg alloy. Gels 2022 8:242. https://doi.org/10.3390/GELS804024210.3390/GELS8040242 ↗
30. Zhou WR, Zheng YF (2015) Characterization of modified magnesium and magnesium alloys for biomedical applications. In: Sankara TSN (ed) Surface Modification of Magnesium and its Alloys for Biomedical Applications, Woodhead Publishing 1:263–282. https://doi.org/10.1016/B978-1-78242-077-4.00008-510.1016/B978-1-78242-077-4.00008-5 ↗
31. Reyes Y, Durán A, Castro Y (2016) Glass-like cerium sol-gel coatings on AZ31B magnesium alloy for controlling the biodegradation of temporary implants. Surf Coat Technol 307:574–582. https://doi.org/10.1016/j.surfcoat.2016.09.05610.1016/j.surfcoat.2016.09.056 ↗
32. Brus J, Spírková M, Hlavatá D, Strachota A Self-Organization, Structure, Dynamic Properties, and Surface Morphology of Silica/Epoxy Films As Seen by Solid-State NMR, SAXS, and AFM. Macromolecules. ACS publications. 37:1346-1357. https://doi.org/10.1021/ma035608h.10.1021/ma035608h ↗
33. Alam TM, Assink RA, Loy DA (1996) Hydrolysis and esterification in organically modified alkoxysilanes: A 29Si NMR investigation of methyltrimethoxysilane. Chem Mater 8:2366–2374. https://doi.org/10.1021/CM960183H. ACS publications10.1021/CM960183H ↗
34. Zou J, Shi W, Hong X (2005) Characterization and properties of a novel organic–inorganic hybrid based on hyperbranched aliphatic polyester prepared via sol-gel process. Compos Part A: Appl Sci Manuf 36:631–637. https://doi.org/10.1016/j.compositesa.2004.08.00110.1016/j.compositesa.2004.08.001 ↗
35. Templin M, Wiesner U, Spiess HW (1997) Multinuclear solid-state-NMR studies of hybrid organic inorganic materials. Adv Mater 9:814–817. https://doi.org/10.1002/ADMA.1997009101110.1002/ADMA.19970091011 ↗
36. Innocenzi P, Brusatin G, Babonneau F (2000) Competitive polymerization between organic and inorganic networks in hybrid materials. Chem Mater 12:3726–3732. https://doi.org/10.1021/CM001139B/ASSET/IMAGES/LARGE/CM001139BF00007.JPEG10.1021/CM001139B/ASSET/IMAGES/LARGE/CM001139BF00007.JPEG ↗
37. Wei J, Yoshinari M, Takemoto S, Hattori M, Kawada E, Liu B et al. (2007) Adhesion of mouse fibroblasts on hexamethyldisiloxane surfaces with wide range of wettability. J Biomed Mater Res B Appl Biomater 81:66–75. https://doi.org/10.1002/JBM.B.3063810.1002/JBM.B.30638 ↗
38. Liu L, Li N, Lei T, Li K, Zhang Y (2014) The in vitro biological properties of Mg-Zn-Sr alloy and superiority for preparation of biodegradable intestinal anastomosis rings. Med Sci Monit 24:1056–66. https://doi.org/10.12659/MSM.89063810.12659/MSM.890638 ↗
39. Gu X, Zheng Y, Cheng Y, Zhong S, Xi T (2009) In vitro corrosion and biocompatibility of binary magnesium alloys. Biomaterials 30:484–498. https://doi.org/10.1016/j.biomaterials.2008.10.02110.1016/j.biomaterials.2008.10.021 ↗