Carvone functionalized iron oxide nanostructures thin films prepared by MAPLE for improved resistance to microbial colonization
Source abstract
Abstract
In this study, we aimed to improve and extend the microbiological applications of magnetic nanocarriers, by the successful fabrication of a new nanostructured surface based on 7 nm average diameter magnetite and carvone (Fe3O4@CAR) nanoparticles and to evaluate the biological activity of this material deposed as a thin film by advanced laser techniques (MAPLE). The results demonstrate that the thin surfaces containing the fabricated bio-active nanosystem have a great antimicrobial activity, inhibiting the colonization and biofilm formation of both Gram positive and Gram negative tested species. Furthermore, the in vitro results demonstrate that this material is not cytotoxic, allowing the normal growth and development of human endothelial cells. Our results demonstrate that the fabricated magnetic bioactive nanostructured surfaces have a great potential to be used for the development of novel applications on the medical field, particularly in the control of infectious diseases.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Laser-Ablation Synthesis of Nanoparticles
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References (37)
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