Spinel ZnCr2O4 nanorods synthesized by facile sol-gel auto combustion method with biomedical properties
Source abstract
Abstract
In this study, spinel zinc chromite nanorods (ZnCr2O4 NRs) were successfully manipulated by a simple sol-gel auto combustion process employing urea as fuel. The sample was only required to sinter at 500 °C for 2 h to obtain the single crystalline phase. The phase formation, crystallinity, and surface topography of synthesized ZnCr2O4 NRs were explored by X-ray diffraction (XRD), UV-Vis reflectance spectroscopy (UVDRS), Fourier transform infrared (FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray (EDX) spectroscopy, and vibrating sample magnetometry (VSM). XRD analysis confirms the formation of spinel ZnCr2O4 NRs. The FTIR spectrum displays the two vibrational peaks of Cr-O, and Zn-O at 489 and 615 cm-1, correspondingly. These vibrational bonds were correlated with ZnCr2O4 and revealed the production of cubic spinel ZnCr2O4 NRs. FESEM indicates the presence of hexagonal-rod-shaped particles. EDX spectrum demonstrates the elemental composition of the ZnCr2O4 NRs and confirms the primary peak of Zn, Cr, and O. The obtained ZnCr2O4 NRs exhibit an antiferromagnetic behavior. The bandgap energy of ZnCr2O4 NRs was ascertained and was shown to be 3.45 eV. Furthermore, the antifungal and antibacterial effect of ZnCr2O4 NRs was examined against pathogenic strains by disc diffusion technique. Besides these, the antimalarial activity of ZnCr2O4 NRs was studied against Plasmodium falciparum. Thus, the as-synthesized ZnCr2O4 NRs showed significant antibacterial, antifungal and antimalarial activity and may be helpful for research opening a novel horizon in nanomedicine. Graphical abstract.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Advanced Nanomaterials in Catalysis · Advanced Photocatalysis Techniques · Nanoparticles: synthesis and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (65)
Show source-provided references
1. Khan I, Saeed K, Khan I (2019) Nanoparticles: properties, applications and toxicities. Arab J Chem 12:908–93110.1016/j.arabjc.2017.05.011 ↗
2. Gawande MB, Goswami A, Felpin F-X, Asefa T, Huang X, Silva R, Zou X, Zboril R, Varma RS (2016) Cu and Cu-based nanoparticles: synthesis and applications in catalysis. Chem Rev 116:3722–381110.1021/acs.chemrev.5b00482 ↗
3. Cuong HN, Pansambal S, Ghotekar S, Oza R, Hai NTT, Viet NM, Nguyen V-H (2022) New frontiers in the plant extract mediated biosynthesis of copper oxide (CuO) nanoparticles and their potential applications: a review. Environ Res 203:11185810.1016/j.envres.2021.111858 ↗
4. Calderón-Jiménez B, Johnson ME, Montoro Bustos AR, Murphy KE, Winchester MR, Vega Baudrit JR (2017) Silver nanoparticles: technological advances, societal impacts, and metrological challenges. Front Chem 5:610.3389/fchem.2017.00006 ↗
5. Dabhane H, Ghotekar SK, Tambade PJ, Pansambal S, Ananda Murthy H, Oza R, Medhane V (2021) Cow urine mediated green synthesis of nanomaterial and their applications: a state-of-the-art review. J Water Environ Nanotechnol 6:81–91
6. Sridhar A, Ponnuchamy M, Kumar PS, Kapoor A (2021) Food preservation techniques and nanotechnology for increased shelf life of fruits, vegetables, beverages and spices: a review. Environ Chem Lett 19:1715–173510.1007/s10311-020-01126-2 ↗
7. Ghotekar S, Pansambal S, Bilal M, Pingale SS, Oza R (2021) Environmentally friendly synthesis of Cr2O3 nanoparticles: Characterization, applications and future perspective─ a review. Case Stud Chem Environ Eng 3:10008910.1016/j.cscee.2021.100089 ↗
8. Hajipour MJ, Akhavan O, Meidanchi A, Laurent S, Mahmoudi M (2014) Hyperthermia-induced protein corona improves the therapeutic effects of zinc ferrite spinel-graphene sheets against cancer. RSC Adv 4:62557–6256510.1039/C4RA10862K ↗
9. Sharma K, Raizada P, Hasija V, Singh P, Bajpai A, Nguyen V-H, Rangabhashiyam S, Kumar P, Nadda AK, Kim SY (2021) ZnS-based quantum dots as photocatalysts for water purification. J Water Process Eng 43:10221710.1016/j.jwpe.2021.102217 ↗
10. Abdolmaleki A, Asadi A, Gurushankar K, Shayan TK, Sarvestani FA (2021) Importance of nano medicine and new drug therapies for cancer. Adv Pharm Bull 11:45010.34172/apb.2021.052 ↗
11. Ebrahimi M, Asadi M, Akhavan O (2021) Graphene-based nanomaterials in fighting the most challenging viruses and immunogenic disorders. ACS Biomater Sci Eng 8:54–8110.1021/acsbiomaterials.1c01184 ↗
12. Fardood ST, Forootan R, Moradnia F, Afshari Z, Ramazani A (2020) Green synthesis, characterization, and photocatalytic activity of cobalt chromite spinel nanoparticles. Mater Res Express 7:01508610.1088/2053-1591/ab6c8d ↗
13. Eivazzadeh-Keihan R, Aliabadi HAM, Radinekiyan F, Sobhani M, Maleki A, Madanchi H, Mahdavi M, Shalan AE (2021) Investigation of the biological activity, mechanical properties and wound healing application of a novel scaffold based on lignin–agarose hydrogel and silk fibroin embedded zinc chromite nanoparticles. RSC Adv 11:17914–1792310.1039/D1RA01300A ↗
14. Mahapatra PL, Das S, Mondal PP, Das T, Saha D, Pal M (2021) Microporous copper chromite thick film based novel and ultrasensitive capacitive humidity sensor. J Alloy Compd 859:15777810.1016/j.jallcom.2020.157778 ↗
15. Javed M, Khan AA, Kazmi J, Mohamed MA, Khan MN, Hussain M, Bilkees R (2021) Dielectric relaxation and small polaron hopping transport in sol-gel-derived NiCr2O4 spinel chromite. Mater Res Bull 138:11124210.1016/j.materresbull.2021.111242 ↗
16. Meidanchi A, Akhavan O (2014) Superparamagnetic zinc ferrite spinel–graphene nanostructures for fast wastewater purification. Carbon 69:230–23810.1016/j.carbon.2013.12.019 ↗
17. Malaie K, Ganjali MR (2021) Spinel nano-ferrites for aqueous supercapacitors; linking abundant resources and low-cost processes for sustainable energy storage. J Energy Storage 33:10209710.1016/j.est.2020.102097 ↗
18. Syed A, Elgorban AM, Bahkali AH, Zaghloul NS (2021) Coupling of nano-spinel MgFe2O4 on Co3O4 for heterogeneous photocatalysis and antibacterial applications: Insights of optoelectrical properties, Colloid and Interface Science. Communications 44:100467
19. Kalia R, Chauhan A, Verma R, Sharma M, Batoo KM, Kumar R, Hussain S, Ghotekar S, Ijaz MF (2022) Photocatalytic Degradation Properties of Li‐Cr Ions Substituted CoFe2O4 Nanoparticles for Wastewater Treatment Application. Phys Status Solidi (a) 219:210053910.1002/pssa.202100539 ↗
20. Pansambal S, Ghotekar S, Shewale S, Deshmukh K, Barde N, Bardapurkar P (2019) Efficient synthesis of magnetically separable CoFe2O4@ SiO2 nanoparticles and its potent catalytic applications for the synthesis of 5-aryl-1, 2, 4-triazolidine-3-thione derivatives. J Water Environ Nanotechnol 4:174–186
21. Akhavan O, Meidanchi A, Ghaderi E, Khoei S (2014) Zinc ferrite spinel-graphene in magneto-photothermal therapy of cancer. J Mater Chem B 2:3306–331410.1039/c3tb21834a ↗
22. Meidanchi A, Akhavan O, Khoei S, Shokri AA, Hajikarimi Z, Khansari N (2015) ZnFe2O4 nanoparticles as radiosensitizers in radiotherapy of human prostate cancer cells. Mater Sci Eng: C 46:394–39910.1016/j.msec.2014.10.062 ↗
23. Peng C, Gao L (2008) Optical and photocatalytic properties of spinel ZnCr2O4 nanoparticles synthesized by a hydrothermal route. J Am Ceram Soc 91:2388–239010.1111/j.1551-2916.2008.02417.x ↗
24. Ghosh D, Dutta U, Haque A, Mordvinova NE, Lebedev OI, Pal K, Gayen A, Seikh MM, Mahata P (2018) Ultra-high sensitivity of luminescent ZnCr2O4 nanoparticles toward nitroaromatic explosives sensing. Dalton Trans 47:5011–501810.1039/C8DT00047F ↗
25. Chavan P, Salve A, Shelke R, Pansare D (2021) A Facile Synthesis and Biological Screening of Pyrimidine Derivatives under Ultrasonic Irradiations by ZnCr2O4 Nano-Particles Catalyst. Lett Appl NanoBioScience 11:2996–300510.33263/LIANBS111.29963005 ↗
26. Niu X, Du W, Du W (2004) Preparation and gas sensing properties of ZnM2O4 (M= Fe, Co, Cr). Sens Actuators B: Chem 99:405–40910.1016/j.snb.2003.12.007 ↗
27. Mousavi Z, Soofivand F, Esmaeili-Zare M, Salavati-Niasari M, Bagheri S (2016) ZnCr2O4 nanoparticles: facile synthesis, characterization and photocatalytic properties. Sci Rep 6:1–1810.1038/s41598-016-0001-8 ↗
28. Poschmann M, Schürmann U, Bensch W, Kienle L (2018) The hazardous origin of photocatalytic activity of ZnCr2O4. Z für anorganische und Allg Chem 644:564–57310.1002/zaac.201800072 ↗
29. Tantubay K, Das P, Sen MB (2021) Hydrogen Peroxide Assisted Photocatalytic Dye Degradation Over Reduced Graphene Oxide Integrated ZnCr2O4 Nanoparticles. Env Sci Poll Res 29:17309–1731810.1007/s11356-021-17105-1 ↗
30. Javed M, Khan AA, Khan MN, Kazmi J, Mohamed MA (2021) Investigation on Non-Debye type relaxation and polaronic conduction mechanism in ZnCr2O4 ternary spinel oxide. Mater Sci Eng: B 269:11516810.1016/j.mseb.2021.115168 ↗
31. Dumitru R, Manea F, Păcurariu C, Lupa L, Pop A, Cioablă A, Surdu A, Ianculescu A (2018) Synthesis, characterization of nanosized ZnCr2O4 and its photocatalytic performance in the degradation of humic acid from drinking water. Catalysts 8:21010.3390/catal8050210 ↗
32. Tajizadegan H, Heidary A, Torabi O, Golabgir MH, Jamshidi A (2016) Synthesis and characterization of ZnCr2O4 nanospinel prepared via homogeneous precipitation using urea hydrolysis. Int J Appl Ceram Technol 13:289–29410.1111/ijac.12440 ↗
33. Mancic L, Marinkovic Z, Vulic P, Moral C, Milosevic O (2003) Morphology, structure and nonstoichiometry of ZnCr2O4 nanophased powder. Sensors 3:415–42310.3390/s31000415 ↗
34. Miranda EAC, Carvajal JFM, Baena OJR (2015) Effect of the fuels glycine, urea and citric acid on synthesis of the ceramic pigment ZnCr2O4 by solution combustion. Mater Res 18:1038–104310.1590/1516-1439.019915 ↗
35. Abdullah OG (2016) Synthesis of single-phase zinc chromite nano-spinel embedded in polyvinyl alcohol films and its effects on energy band gap. J Mater Sci: Mater Electron 27:12106–12111
36. Mousavi Z, Esmaeili-Zare M, Salavati-Niasari M (2015) Magnetic and optical properties of zinc chromite nanostructures prepared by microwave method. Trans Nonferrous Met Soc China 25:3980–398610.1016/S1003-6326(15)64007-9 ↗
37. Huang W, Zha W, Zhao D, Feng S (2019) The effect of active oxygen species in nano-ZnCr2O4 spinel oxides for methane catalytic combustion. Solid State Sci 87:49–5210.1016/j.solidstatesciences.2018.11.006 ↗
38. Bangale S, Bamane S (2013) Preparation and electrical properties of nanostructured spinel ZnCr 2 O 4 by combustion route. J Mater Sci: Mater Electron 24:277–281
39. Naz S, Durrani SK, Mehmood M, Nadeem M (2016) Hydrothermal synthesis, structural and impedance studies of nanocrystalline zinc chromite spinel oxide material. J Saudi Chem Soc 20:585–59310.1016/j.jscs.2014.12.007 ↗
40. Bangale S, Ghotekar S (2019) Bio-fabrication of Silver nanoparticles using Rosa Chinensis L. extract for antibacterial activities. Int J Nano Dimens 10:217–224
41. Pansambal S, Deshmukh K, Savale A, Ghotekar S, Pardeshi O, Jain G, Aher Y, Pore D (2017) Phytosynthesis and biological activities of fluorescent CuO nanoparticles using Acanthospermum hispidum L. extract. J Nanostruct 7:165–174.10.18502/jns.v7i3.1 ↗
42. Pagar K, Ghotekar S, Pagar T, Nikam A, Pansambal S, Oza R, Sanap D, Dabhane H (2020) Antifungal activity of biosynthesized CuO nanoparticles using leaves extract of Moringa oleifera and their structural characterizations. Asian J Nanosci Mater 3:15–23
43. Ghotekar S, Pansambal S, Pawar SP, Pagar T, Oza R, Bangale S (2019) Biological activities of biogenically synthesized fluorescent silver nanoparticles using Acanthospermum hispidum leaves extract. SN Appl Sci 1:1–12.10.1007/s42452-019-1389-0 ↗
44. Rieckmann K, Campbell G, Sax L, Ema J (1978) Drug sensitivity of Plasmodium falciparum: an in-vitro microtechnique. Lancet 311:22–2310.1016/S0140-6736(78)90365-3 ↗
45. Cherifi K, Rekhila G, Omeiri S, Bessekhouad Y, Trari M (2019) Physical and photoelectrochemical properties of the spinel ZnCr2O4 prepared by sol gel: application to Orange II degradation under solar light. J Photochem Photobiol A: Chem 368:290–29510.1016/j.jphotochem.2018.10.003 ↗
46. Sabet M, Jahangiri H (2018) The effects of surfactant on the structure of ZnCr2O4 dendrimer like nanostructures used in degradation of Eriochrome Black T. Mater Res Express 5:01503510.1088/2053-1591/aaa442 ↗
47. Gene SA, Saion E, Shaari AH, Kamarudin MA, Al-Hada NM, Kharazmi A (2014) Structural, optical, and magnetic characterization of spinel zinc chromite nanocrystallines synthesised by thermal treatment method. J Nanomater 2014:1–1510.1155/2014/416765 ↗
48. Stefanescu M, Barbu M, Vlase T, Barvinschi P, Barbu-Tudoran L, Stoia M (2011) Novel low temperature synthesis method for nanocrystalline zinc and magnesium chromites. Thermochim Acta 526:130–13610.1016/j.tca.2011.09.005 ↗
49. Gingasu D, Mindru I, Patron L, Culita DC, Calderon-Moreno JM, Diamandescu L, Feder M, Oprea O (2013) Precursor method—A nonconventional route for the synthesis of ZnCr2O4 spinel. J Phys Chem Solids 74:1295–130210.1016/j.jpcs.2013.04.007 ↗
50. Rhee JY, Singh N (2010) Electronic structures and optical properties of spinel ZnCr2O4. J Korean Phys Soc 57:1233–123710.3938/jkps.57.1233 ↗
51. Tauc J, Grigorovici R, Vancu A (1966) Optical properties and electronic structure of amorphous germanium. Phys Status Solidi (b) 15:627–63710.1002/pssb.19660150224 ↗
52. Liang Z, Guang-Fu J, Feng Z, Zi-Zheng G (2011) First-principles study of the structural, mechanical and electronic properties of ZnX2O4 (X= Al, Cr and Ga). Chin Phys B 20:04710210.1088/1674-1056/20/4/047102 ↗
53. Abbasi A, Hamadanian M, Salavati-Niasari M, Mortazavi-Derazkola S (2017) Facile size-controlled preparation of highly photocatalytically active ZnCr2O4 and ZnCr2O4/Ag nanostructures for removal of organic contaminants. J Coll Interfac Sci 500:276–28410.1016/j.jcis.2017.04.003 ↗
54. Kassem MA, El-Fadl AA, Nashaat AM, Nakamura H (2019) Structure, optical and varying magnetic properties of insulating MCr2O4 (M= Co, Zn, Mg and Cd) nanospinels. J Alloy Compd 790:853–86210.1016/j.jallcom.2019.03.189 ↗
55. Taheri A, Ziaadini M, Gahramzai M (2021) Antibacterial Properties Study of Synthetic Nanocomposite Zinc Chromite-Zinc Aluminate (ZnCr2O4-ZnAl2O4) Against Escherichia coli and Pseudomonas aeruginosa. J Vet Res 76:304–314
56. Akhavan O, Ghaderi E (2010) Toxicity of graphene and graphene oxide nanowalls against bacteria. ACS Nano 4:5731–573610.1021/nn101390x ↗
57. Dutta T, Sarkar R, Pakhira B, Ghosh S, Sarkar R, Barui A, Sarkar S (2015) ROS generation by reduced graphene oxide (rGO) induced by visible light showing antibacterial activity: comparison with graphene oxide (GO). RSC Adv 5:80192–8019510.1039/C5RA14061G ↗
58. Lakshmi Prasanna V, Vijayaraghavan R (2015) Insight into the mechanism of antibacterial activity of ZnO: surface defects mediated reactive oxygen species even in the dark. Langmuir 31:9155–916210.1021/acs.langmuir.5b02266 ↗
59. Akhavan O, Ghaderi E, Esfandiar A (2011) Wrapping bacteria by graphene nanosheets for isolation from environment, reactivation by sonication, and inactivation by near-infrared irradiation. J Phys Chem B 115:6279–628810.1021/jp200686k ↗
60. Liu S, Zeng TH, Hofmann M, Burcombe E, Wei J, Jiang R, Kong J, Chen Y (2011) Antibacterial activity of graphite, graphite oxide, graphene oxide, and reduced graphene oxide: membrane and oxidative stress. ACS Nano 5:6971–698010.1021/nn202451x ↗
61. Akhavan O, Ghaderi E (2012) Escherichia coli bacteria reduce graphene oxide to bactericidal graphene in a self-limiting manner. Carbon 50:1853–186010.1016/j.carbon.2011.12.035 ↗
62. Kumar A, Pandey AK, Singh SS, Shanker R, Dhawan A (2011) Engineered ZnO and TiO2 nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli. Free Radic Biol Med 51:1872–188110.1016/j.freeradbiomed.2011.08.025 ↗
63. Wang Y-W, Cao A, Jiang Y, Zhang X, Liu J-H, Liu Y, Wang H (2014) Superior antibacterial activity of zinc oxide/graphene oxide composites originating from high zinc concentration localized around bacteria. ACS Appl Mater interfac 6:2791–279810.1021/am4053317 ↗
64. Jannesari M, Akhavan O, Madaah Hosseini HR, Bakhshi B (2020) Graphene/CuO2 nanoshuttles with controllable release of oxygen nanobubbles promoting interruption of bacterial respiration. ACS Appl Mater interfac 12:35813–3582510.1021/acsami.0c05732 ↗
65. Xie Y, He Y, Irwin PL, Jin T, Shi X (2011) Antibacterial activity and mechanism of action of zinc oxide nanoparticles against Campylobacter jejuni. Appl Environ Microbiol 77:2325–233110.1128/AEM.02149-10 ↗