Effects of different amounts of APTES on physicochemical and structural properties of amino-functionalized MCM-41-MSNs
Source abstract
Abstract
Mesoporous silica nanoparticles (MSNs) are frequently functionalized to be used for specific applications, including catalysis and biomedical engineering. In this research, MCM-41-MSNs were synthesized by the sol–gel method and were functionalized with different quantities of (3-aminopropyl) triethoxysilane (APTES) using a post-grafting method to determine the physicochemical and structural changes in the MSNs. The functionalized materials were assessed by different characterization techniques, namely, TGA, FTIR, BET, SEM, TEM, DLS, zeta potential, SAXS, XRD and XPS. The FTIR data confirmed the presence of amino groups on the MSN surfaces, and the results from the XPS, TGA and zeta potential demonstrated that the APTES concentration during post-grafting directly affects the quantity of amino groups bound to the MSNs. The SAXS, TEM and nitrogen adsorption–desorption analyses showed that as the amount of APTES in the MSNs increases, the mesoporous structure become more disordered.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Mesoporous Materials and Catalysis · Adsorption and biosorption for pollutant removal · Aerogels and thermal insulation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (49)
Show source-provided references
1. He Q, Gao Y, Zhang L, Zhang Z, Gao F, Ji X, Li Y, Shi J (2011) A pH-responsive mesoporous silica nanoparticles-based multi-drug delivery system for overcoming multi-drug resistance. Biomaterials 32:7711–772010.1016/j.biomaterials.2011.06.066 ↗
2. Avnir D, Coradin T, Lev O, Livage J (2006) Recent bio-applications of sol–gel materials. J Mater Chem 16:1013–103010.1039/B512706H ↗
3. Coradin T, Boissière M, Livage J (2006) Sol–gel chemistry in medicinal science. Curr Med Chem 13:99–10810.2174/092986706789803044 ↗
4. Huang Y (2009) Functionalization of mesoporous silica nanoparticles and their applications in organo-, metallic and organometallic catalysis. Graduate Theses and Dissertations. Paper 10974. http://lib.dr.iastate.edu/etd/10974
5. Zhang Y, Yuan Q, Chen T, Zhang X, Chen Y, Tan W (2012) DNA-capped mesoporous silica nanoparticles as an ion-responsive release system to determine the presence of mercury in aqueous solutions. Anal Chem 84:1956–196210.1021/ac202993p ↗
6. Wittig R, Rosenholm JM, von Haartman E, Hemming J, Genze F, Bergman L, Simmet T, Lindén M, Sahlgren C (2013) Active targeting of mesoporous silica drug carriers enhances γ-secretase inhibitor efficacy in an in vivo model for breast cancer. Nanomedicine 9:1–1710.1016/j.nano.2012.05.013 ↗
7. Silvestri B, Guarnieri D, Luciani G, Costantini A, Netti P, Branda F (2012) Fluorescent (rhodamine), folate decorated and doxorubicin charged, PEGylated nanoparticles synthesis. J Mater Sci Mater Med 23:1697–170410.1007/s10856-012-4634-2 ↗
8. Huang IP, Sun SP, Cheng SH, Lee CH, Wu CY, Yang CS, Lo LW, Lai YK (2011) Enhanced chemotherapy of cancer using pH-sensitive mesoporous silica nanoparticles to antagonize P-glycoprotein-mediated drug resistance. Mol Cancer Ther 10:761–76910.1158/1535-7163.MCT-10-0884 ↗
9. Chen H, Zhen Z, Tang W, Todd T, Chuang Y, Wang L, Pan Z, Xie J (2013) Label-free luminescent mesoporous silica nanoparticles for imaging and drug delivery. Theranostics 3:65010.7150/thno.6668 ↗
10. Lin Y, Tsai C, Huang H, Kuo C, Hung Y, Huang D, Chen Y, Mou C (2005) Well-ordered mesoporous silica nanoparticles as cell markers. Chem Mater 17:4570–457310.1021/cm051014c ↗
11. Luo Z, Cai K, Hu Y, Zhao L, Liu P, Duan L, Yang W (2011) Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery. Angew Chem Int Ed 50:640–64310.1002/anie.201005061 ↗
12. Agostini A, Mondragón L, Coll C, Aznar E, Marcos MD, Martínez-Máñez R, Sancenón F, Soto J, Pérez-Payá E, Amorós P (2012) Dual enzyme-triggered controlled release on capped nanometric silica mesoporous supports. ChemistryOpen 1:17–2010.1002/open.201200003 ↗
13. Kamarudin N, Jalil A, Triwahyono S, Salleh N, Karim A, Mukti R, Hameed B, Ahmad A (2013) Role of 3-aminopropyltriethoxysilane in the preparation of mesoporous silica nanoparticles for ibuprofen delivery: effect on physicochemical properties. Microporous Mesoporous Mater 180:235–24110.1016/j.micromeso.2013.06.041 ↗
14. Lim MH, Stein A (1999) Comparative studies of grafting and direct syntheses of inorganic-organic hybrid mesoporous materials. Chem Mater 11:3285–329510.1021/cm990369r ↗
15. Chung P, Kumar R, Pruski M, Lin VS (2008) Temperature responsive solution partition of organic-inorganic hybrid poly (N-isopropylacrylamide)-coated mesoporous silica nanospheres. Adv Funct Mater 18:1390–139810.1002/adfm.200701116 ↗
16. de Oliveira Freitas LB, Bravo IJ, de Almeida Macedo WA, de Sousa EM (2015) Mesoporous silica materials functionalized with folic acid: preparation, characterization and release profile study with methotrexate. J Sol Gel Sci Technol 77:1–19
17. Brochier Salon M, Belgacem MN (2011) Hydrolysis-condensation kinetics of different silane coupling agents. Phosphorus, Sulfur, and Silicon 186:240–25410.1080/10426507.2010.494644 ↗
18. Costa JA, Garcia AC, Santos DO, Sarmento VH, de Mesquita ME, Romão LP (2015) Applications of inorganic–organic mesoporous materials constructed by self-assembly processes for removal of benzo[k]fluoranthene and benzo[b]fluoranthene. J Sol Gel Sci Technol 75:495–50710.1007/s10971-015-3720-6 ↗
19. DenizáYilmaz M, FraseráStoddart J (2015) Esterase-and pH-responsive poly (β-amino ester)-capped mesoporous silica nanoparticles for drug delivery. Nanoscale 7:7178–718310.1039/C4NR07443B ↗
20. Du L, Liao S, Khatib HA, Stoddart JF, Zink JI (2009) Controlled-access hollow mechanized silica nanocontainers. J Am Chem Soc 131:15136–1514210.1021/ja904982j ↗
21. Feng W, Zhou X, He C, Qiu K, Nie W, Chen L, Wang H, Mo X, Zhang Y (2013) Polyelectrolyte multilayer functionalized mesoporous silica nanoparticles for pH-responsive drug delivery: layer thickness-dependent release profiles and biocompatibility. J Mater Chem B 1:5886–589810.1039/c3tb21193b ↗
22. Tang H, Guo J, Sun Y, Chang B, Ren Q, Yang W (2011) Facile synthesis of pH sensitive polymer-coated mesoporous silica nanoparticles and their application in drug delivery. Int J Pharm 421:388–39610.1016/j.ijpharm.2011.10.013 ↗
23. Huang Y, Trewyn BG, Chen H, Lin VS (2008) One-pot reaction cascades catalyzed by base-and acid-functionalized mesoporous silica nanoparticles. New J Chem 32:1311–131310.1039/b806664g ↗
24. Huang Y, Deng W, Guo E, Chung P, Chen S, Trewyn BG, Brown RC, Lin VS (2012) Mesoporous silica nanoparticle-stabilized and manganese-modified rhodium nanoparticles as catalysts for highly selective synthesis of ethanol and acetaldehyde from syngas. ChemCatChem 4:674–68010.1002/cctc.201100460 ↗
25. Zhang Y, Zhi Z, Jiang T, Zhang J, Wang Z, Wang S (2010) Spherical mesoporous silica nanoparticles for loading and release of the poorly water-soluble drug telmisartan. J Controll Release 145:257–26310.1016/j.jconrel.2010.04.029 ↗
26. Meng H, Xue M, Xia T, Zhao Y, Tamanoi F, Stoddart JF, Zink JI, Nel AE (2010) Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves. J Am Chem Soc 132:12690–1269710.1021/ja104501a ↗
27. Rahman I, Jafarzadeh M, Sipaut C (2009) Synthesis of organo-functionalized nanosilica via a co-condensation modification using γ-aminopropyltriethoxysilane (APTES). Ceram Int 35:1883–188810.1016/j.ceramint.2008.10.028 ↗
28. Ritter H, Nieminen M, Karppinen M, Brühwiler D (2009) A comparative study of the functionalization of mesoporous silica MCM-41 by deposition of 3-aminopropyltriethoxysilane from toluene and from the vapor phase. Microporous Mesoporous Mater 121:79–8310.1016/j.micromeso.2009.01.006 ↗
29. Rapp JL, Huang Y, Natella M, Cai Y, Lin VS, Pruski M (2009) A solid-state NMR investigation of the structure of mesoporous silica nanoparticle supported rhodium catalysts. Solid State Nucl Magn Reson 35:82–8610.1016/j.ssnmr.2008.12.004 ↗
30. Chang B, Sha X, Guo J, Jiao Y, Wang C, Yang W (2011) Thermo and pH dual responsive, polymer shell coated, magnetic mesoporous silica nanoparticles for controlled drug release. J Mater Chem 21:9239–924710.1039/c1jm10631g ↗
31. Lee D, Hong JW, Park C, Lee H, Lee JE, Hyeon T, Paik SR (2014) Ca2 -dependent intracellular drug delivery system developed with “raspberry-type” particles-on-a-particle comprising mesoporous silica core and α-synuclein-coated gold nanoparticles. ACS Nano 8:8887–889510.1021/nn5034955 ↗
32. Rim HP, Min KH, Lee HJ, Jeong SY, Lee SC (2011) pH-Tunable calcium phosphate covered mesoporous silica nanocontainers for intracellular controlled release of guest drugs. Angew Chem Int Ed 50:8853–885710.1002/anie.201101536 ↗
33. Meng H, Liong M, Xia T, Li Z, Ji Z, Zink JI, Nel AE (2010) Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. ACS Nano 4:4539–455010.1021/nn100690m ↗
34. Szegedi A, Popova M, Goshev I, Mihály J (2011) Effect of amine functionalization of spherical MCM-41 and SBA-15 on controlled drug release. J Solid State Chem 184:1201–120710.1016/j.jssc.2011.03.005 ↗
35. Manzano M, Aina V, Arean C, Balas F, Cauda V, Colilla M, Delgado M, Vallet-Regi M (2008) Studies on MCM-41 mesoporous silica for drug delivery: effect of particle morphology and amine functionalization. Chem Eng J 137:30–3710.1016/j.cej.2007.07.078 ↗
36. Lim MH, Blanford CF, Stein A (1997) Synthesis and characterization of a reactive vinyl-functionalized MCM-41: probing the internal pore structure by a bromination reaction. J Am Chem Soc 119:4090–409110.1021/ja9638824 ↗
37. de Oliveira Freitas LB, Bravo IJG, de Almeida Macedo WA, de Sousa EM (2015) Mesoporous silica materials functionalized with folic acid: preparation, characterization and release profile study with methotrexate. J Sol Gel Sci Technol 1–19
38. Jakša G, Štefane B, Kovač J (2013) XPS and AFM characterization of aminosilanes with different numbers of bonding sites on a silicon wafer. Surf Interface Anal 45(11–12):1709–171310.1002/sia.5311 ↗
39. Kecht J, Schlossbauer A, Bein T (2008) Selective functionalization of the outer and inner surfaces in mesoporous silica nanoparticles. Chem Mater 20:7207–721410.1021/cm801484r ↗
40. Rosenholm JM, Meinander A, Peuhu E, Niemi R, Eriksson JE, Sahlgren C, Lindén M (2008) Targeting of porous hybrid silica nanoparticles to cancer cells. ACS Nano 3:197–20610.1021/nn800781r ↗
41. Stuart BH (2004) Organic molecules. In: Ando DJ, Dartford K (eds) Infrared spectroscopy: fundamentals and applications, vol 1. Wiley, Chichester, pp 71–8010.1002/0470011149 ↗
42. Maria Chong A, Zhou X (2003) Functionalization of SBA-15 with APTES and characterization of functionalized materials. J Phys Chem B 107:12650–1265710.1021/jp035877+ ↗
43. Kleitz F, Schmidt W, Schüth F (2003) Calcination behavior of different surfactant-templated mesostructured silica materials. Microporous Mesoporous Mater 65:1–2910.1016/S1387-1811(03)00506-7 ↗
44. Kecht J, Bein T (2008) Oxidative removal of template molecules and organic functionalities in mesoporous silica nanoparticles by H2O2 treatment. Microporous Mesoporous Mater 116:123–13010.1016/j.micromeso.2008.03.027 ↗
45. Zhang J, Li X, Rosenholm JM, Gu H (2011) Synthesis and characterization of pore size-tunable magnetic mesoporous silica nanoparticles. J Colloid Interface Sci 361:16–2410.1016/j.jcis.2011.05.038 ↗
46. Lu S, Wang D, Jiang SP, Xiang Y, Lu J, Zeng J (2010) HPW/MCM-41 phosphotungstic acid/mesoporous silica composites as novel proton-exchange membranes for elevated-temperature fuel cells. Adv Mater 22:971–97610.1002/adma.200903091 ↗
47. Landau M, Varkey S, Herskowitz M, Regev O, Pevzner S, Sen T, Luz Z (1999) Wetting stability of Si-MCM-41 mesoporous material in neutral, acidic and basic aqueous solutions. Microporous Mesoporous Mater 33:149–16310.1016/S1387-1811(99)00133-X ↗
48. Mello MR, Phanon D, Silveira GQ, Llewellyn PL, Ronconi CM (2011) Amine-modified MCM-41 mesoporous silica for carbon dioxide capture. Microporous Mesoporous Mater 143:174–17910.1016/j.micromeso.2011.02.022 ↗
49. Chen C, Li H, Davis ME (1993) Studies on mesoporous materials: I. Synthesis and characterization of MCM-41. Microporous Mater 2:17–2610.1016/0927-6513(93)80058-3 ↗