Room-Temperature Persistent Phosphorescence of Aggregated Gold Nanoclusters under Molecular Crystal Confinements

We report color-tunable and solvent-processable persistent fluorescence to phosphorescence switching at room temperature by doping gold nanoclusters (AuNCs) inside molecular crystals. This provides a significant insight into the tunability of the photoluminescence property of the dopant depending on the crystal environment and compactness of confinement, with the possibility of energy transfer from crystal to aggregated AuNCs. For test cases, we have doped histidine-stabilized AuNCs (HIS-AuNCs) inside histidine (HIS-AuNCs-HIS) and isophthalic acid (HIS-AuNCs-IPA) crystals, respectively, and glutathione-stabilized AuNCs (GSH-AuNCs) inside histidine crystals (GSH-AuNCs-HIS). The maximal phosphorescence decay time recorded for crystal doped aggregated AuNCs was 9.38 ms, and the photoluminescence quantum yield value was measured as 25%. The possible energy states and potential interactions between aggregated NCs and host crystals were accounted for through density functional theory calculations and docking techniques, respectively. This finding opens new possibilities for designing and producing color-tunable persistent AuNC-based luminous crystals for multilayer information encryption, display, and biological applications.