journal article·2019-08-01Open access

Confinement and Time Immemorial: Prebiotic Synthesis of Nucleotides on a Porous Mineral Nanoreactor

Francisco Rodrigues, Thomas Georgelin, Guillaume Gabant, Baptiste Rigaud, Fabrice Gaslain, Guanzheng Zhuang, Maria Gardênnia da Fonseca, Valentin Valtchev, David Touboul, Maguy Jaber

Abstract

We report the successful one-pot synthesis of adenosine mono-, di-, and triphosphate in the confined space of a mordenite zeolite. This is also the first report of ATP synthesized onto a porous mineral surface. The results revealed a plausible prebiotic route to ribonucleotides and highlighted the contribution of microporous minerals in the origins of life.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Origins and Evolution of Life · Enzyme Structure and Function · RNA and protein synthesis mechanisms

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Sorbonne University, CNRS UMR 8220, Laboratoire d’Archéologie Moléculaire et Structurale, 4 Place Jussieu, F-75005 Paris, France

Department of Chemistry, State University of Paraíba, UEPB, Campina Grande, Paraíba 58429-500, Brazil

Centre de Biophysique Moléculaire, CNRS, Rue Charles Sadron, 45000 Orléans, France

CNRS Institut des Matériaux de Paris Centre (FR2482), 4 Place Jussieu, 75005 Paris, France

MINES ParisTech, PSL - Research University, MAT - Centre des Matériaux, CNRS UMR 7633, BP 87, F-91003 Evry, France

Department of Chemistry, Federal University of Paraíba, UFPB, João Pessoa, Paraíba 58059-900, Brazil

Normandy University, Laboratoire Catalyse & Spectrochimie, ENSICAEN, 6 bl Maréchal Juin, 14050 Caen, France

CNRS-Institut de Chimie des Substances Naturelles, UPR2301, Université Paris-Saclay, 91198 Gif-sur-Yvette cedex, France

Funding

Governo Brasil · Centre National de la Recherche Scientifique · ?le-de-France

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