Can the Electron-Accepting Properties of Odorants Be Involved in Their Recognition by the Olfactory System?
Source abstract
Abstract
The present study examines the possible importance of the electron-accepting properties of odorant molecules and, in particular, the formation and decay of temporary negative ions via low-energy electron attachment as a possible contribution toward understanding odorant recognition by olfactory receptors (ORs). Fragments formed by dissociative electron attachment (DEA) of mustard oil odorants represented by a series of isothiocyanates are studied experimentally using DEA spectroscopy and DFT calculations. Relative intensities for the most abundant fragment species, S – and SCN –, are found to be characteristic of structurally similar odorants under investigation. This novel approach for the investigation of odorants may contribute to understanding the initial stages of the olfactory process and may provide a means to distinguish between odorants and their interactions with the olfactory receptor system.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Olfactory and Sensory Function Studies · Advanced Chemical Sensor Technologies · Biochemical Analysis and Sensing Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Molecule and Crystal Physics, Ufa Federal Research Centre, Russian Academy of Sciences, Prospeκt Oktyabrya 151, 450075 Ufa, Russia
St. Petersburg State University, Universitetskaya nab. 7/9, 199034 St. Petersburg, Russia
Dipartimento di Chimica “G. Ciamician”, Università di Bologna, via Selmi 2, 40126 Bologna, Italy
Centro Interdipartimentale di Ricerca in Scienze Ambientali, via S. Alberto 163, 48123 Ravenna, Italy
ISOF, Istituto per la Sintesi Organica e la Fotoreattività, C.N.R., via Gobetti 101, 40129 Bologna, Italy
Funding
Russian Foundation for Basic Research · Italian Ministero dell?Istruzione, dell?Universit? e della Ricerca
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