Towards structurally new cyanine dyes—investigating the photophysical and potential antifungal properties of linear substituted heptamethine dyes

Okoh Adeyi Okoh; Clare L. Lawrence; Roger H. Bisby; Sarah L. Brennan; Robert B. Smith

doi:10.1111/cote.12780

journal article·2025-02Open access

Towards structurally new cyanine dyes—investigating the photophysical and potential antifungal properties of linear substituted heptamethine dyes

Okoh Adeyi Okoh, Clare L. Lawrence, Roger H. Bisby, Sarah L. Brennan, Robert B. Smith

Coloration Technology· Volume 141· Issue 1

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Source abstract

Abstract

Abstract The synthesis of a range of new linear substituted heptamethine dyes has been designed and described. The photophysical properties of all the dyes were investigated, with many exhibiting improved fluorescent quantum yields when compared with indocyanine green. Finally, growth inhibition studies were performed in the fission yeast Saccharomyces pombe , which suggests potential antifungals activity in the μM range.

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Research context

OpenAlex topics: Click Chemistry and Applications · Redox biology and oxidative stress · Photodynamic Therapy Research Studies

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Affiliations

Institute for Materials and Investigative Sciences University of Central Lancashire Preston UK

School of Pharmacy and Biomedical Sciences University of Central Lancashire Preston UK

School of Environment and Life Sciences University of Salford Salford UK

Funding

Faculty of Science and Technology, Pokhara University · University of Central Lancashire

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