Morphology and cell responses of three-dimensional porous silica nanofibrous scaffold prepared by sacrificial template method
Source abstract
Abstract
Abstract Three-dimensional (3D) nanofibrous scaffolds morphologically mimicking natural extracellular matrix show great potential in the application of tissue repair. Herein, we report a novel 3D nanofibrous silica (SiO 2 ) scaffold fabricated via a sacrificial template method. The sacrificed template used was 3D bacterial cellulose and the resultant silica nanofiber has a ultrasmall diameter of 21 nm. SEM, TEM, and AFM evidence the 3D porous nanofibrous structure and pore structure measurement confirms the existence of macro- and meso-pores in the as-prepared silica scaffold. Cell studies using osteoblast cells demonstrate excellent biocompatibility and high ALP activity. These results suggest that the 3D silica nanofibrous scaffold is a promising candidate for hard tissue engineering.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Diatoms and Algae Research · Bone Tissue Engineering Materials · Mesoporous Materials and Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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