journal article·2006-11

Dielectric study of the viscous and glassy states of a binary, nifedipine-based pharmaceutical alloy

T. El Goresy, R. Böhmer

Journal of Non-Crystalline Solids· Volume 352· Issue 42-49
Publisher page

Abstract

An equimolar mixture of nifedipine and acetaminophen was studied in its supercooled liquid and in its glassy state using dielectric spectroscopy. It is found that this alloy is characterized by a relatively large steepness index m = 83. The low-temperature relaxation of pure nifedipine is studied and compared with that of the mixture.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Material Dynamics and Properties · Thermodynamic properties of mixtures · Liquid Crystal Research Advancements

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (48)

Show source-provided references
1. Craig · Int. J. Pharm. · 1999 · 179 · 17910.1016/S0378-5173(98)00338-X ↗
2. Yu · Adv. Drug Deliv. Rev. · 2001 · 48 · 2710.1016/S0169-409X(01)00098-9 ↗
3. Aso · J. Pharm. Sci. · 2000 · 89 · 40810.1002/(SICI)1520-6017(200003)89:3<408::AID-JPS11>3.0.CO;2-# ↗
4. Johari · Phys. Chem. Chem. Phys. · 2000 · 2 · 547910.1039/b007086f ↗
5. R. Nath, T. El Goresy, B. Geil, H. Zimmermann, R. Böhmer, Phys. Rev. E, in press, and references cited therein.
6. Johari · J. Pharm. Sci. · 2005 · 94 · 220710.1002/jps.20455 ↗
7. Mullins · J. Am. Pharm. Assoc. Sci. Ed. · 1960 · 49 · 24510.1002/jps.3030490417 ↗
8. Kerč · Thermochim. Acta · 1995 · 248 · 8110.1016/0040-6031(94)01949-H ↗
9. Lunkenheimer · Contemp. Phys. · 2000 · 41 · 1510.1080/001075100181259 ↗
10. See, e.g., the Proceedings of the International Discussion Meetings on Relaxation in Complex Systems, published in J. Non-Cryst. Solids 131 (1991); 172 (1994); 235 (1998); 307 (2002).
11. Fan · Thermochim. Acta · 1995 · 266 · 910.1016/0040-6031(95)02551-0 ↗
12. Descamps · J. Phys. Chem. B · 2005 · 109 · 1609210.1021/jp040494c ↗
13. Miyashita · J. Phys. Chem. B · 2005 · 109 · 195910.1021/jp046736q ↗
14. Johari · J. Chem. Phys. · 1970 · 53 · 237210.1063/1.1674335 ↗
15. Broadband dielectric spectroscopy, in: F. Kremer, A. Schönhals (Eds.), Springer, Berlin, 2002.
16. Ngai · J. Chem. Phys. · 2004 · 120 · 85710.1063/1.1630295 ↗
17. Roland · Rep. Prog. Phys. · 2005 · 68 · 140510.1088/0034-4885/68/6/R03 ↗
18. Böhmer · Prog. NMR Spectrosc. · 2001 · 39 · 19110.1016/S0079-6565(01)00036-X ↗
19. Vogel · Annu. Rep. NMR Spectrosc. · 2005 · 56 · 201
20. Schneider · Phys. Rev. Lett. · 2000 · 84 · 556010.1103/PhysRevLett.84.5560 ↗
21. Döß · Phys. Rev. Lett. · 2002 · 88 · 09570110.1103/PhysRevLett.88.095701 ↗
22. Döß · J. Chem. Phys. · 2002 · 117 · 658210.1063/1.1506147 ↗
23. Ngai · Phys. Rev. E · 1998 · 57 · 734610.1103/PhysRevE.57.7346 ↗
24. Ngai · J. Chem. Phys. · 1998 · 109 · 698210.1063/1.477334 ↗
25. B. Geil, G. Diezemann, R. Böhmer, Phys. Rev. E, submitted for publication.
26. A. Nowaczyk, B. Geil, G. Hinze, R. Böhmer, Phys. Rev. E, submitted for publication.
27. Hansen · J. Phys.: Condens. Matter · 1997 · 9 · 9661
28. Gainaru · Phys. Rev. B · 2005 · 72 · 17420310.1103/PhysRevB.72.174203 ↗
29. Ngai · J. Phys.: Condens. Matter · 2003 · 15 · S1107
30. Aso · Chem. Pharm. Bull. · 1995 · 43 · 30010.1248/cpb.43.300 ↗
31. Aso · Chem. Pharm. Bull. · 1996 · 44 · 106510.1248/cpb.44.1065 ↗
32. Zhou · J. Pharm. Sci. · 2002 · 91 · 186310.1002/jps.10169 ↗
33. Martino · Chem. Pharm. Bull. · 2000 · 48 · 110510.1248/cpb.48.1105 ↗
34. Havriliak · J. Polym. Sci. C · 1966 · 14 · 9910.1002/polc.5070140111 ↗
35. Schiener · Science · 1996 · 274 · 75210.1126/science.274.5288.752 ↗
36. Böttcher · 1978 · vol. 2
37. Loidl · Phys. Rev. B · 1986 · 34 · 123810.1103/PhysRevB.34.1238 ↗
38. Böhmer · J. Chem. Phys. · 1993 · 99 · 420110.1063/1.466117 ↗
39. Schug · J. Chem. Phys. · 1998 · 109 · 147210.1063/1.476715 ↗
40. Dyre · Phys. Rev. E · 2004 · 69 · 04250110.1103/PhysRevE.69.042501 ↗
41. Döß · J. Chem. Phys. · 1997 · 107 · 174010.1063/1.474567 ↗
42. Kudlik · J. Mol. Struct. · 1999 · 479 · 20110.1016/S0022-2860(98)00871-0 ↗
43. Ngai · Phys. Rev. E · 2004 · 69 · 03150110.1103/PhysRevE.69.031501 ↗
44. Qi · Phys. Chem. Chem. Phys. · 2001 · 3 · 402210.1039/b102391h ↗
45. Moynihan · J. Chem. Phys. · 1971 · 55 · 301310.1063/1.1676531 ↗
46. Fujimori · Solid State Commun. · 1995 · 94 · 15710.1016/0038-1098(94)00851-5 ↗
47. Donth · 2001
48. Böhmer · Mol. Phys. · 1994 · 82 · 53110.1080/00268979400100394 ↗