A comprehensive investigation of the effect of Ag on the structure and antibacterial efficacy of Li-substituted 58S and 68S bioactive glasses
Source abstract
Abstract
In this study , Ag ions in the systems of 60SiO 2-(31-x)CaO-4P 2O 5–5Li 2O-(x)Ag 2O and 70SiO 2-(21-x)CaO-4P 2O 5–5Li 2O-(x)Ag 2O (where x = 0, 5, 10 mol %) were substituted for Ca to improve their biological properties. The process of in vitro formation of hydroxyapatite (HA) was investigated through Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), and its morphology was observed by scanning electron microscope (SEM) and transmission electron microscopy (TEM). According to the results, doping 5 mol % Ag in the both 58S and 68S systems increased the bioactivity. Based on ICP-AES results, the dissolution rates of specimens were inversely proportional to their oxygen density. Furthermore, the viability, the production of ALP enzyme, and bactericidal activity against MRSA bacteria were improved and resulted in significant statistical differences, while bioactive glass with the chemical composition of 60SiO 2–26CaO-4P 2O 5–5Li 2O-5Ag 2O (58LA05) had the best performance.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Facial Trauma and Fracture Management · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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