Glass formation in the Mg(CH3COO)2–(CH3)2SO–H2О system and the preparation of a low-toxicity cryoprotector
Source abstract
Abstract
Glass formation in the Mg(CH 3COO) 2–(CH 3) 2SO–H 2O system is found to occur and studied by calorimetry, IR spectroscopy, and density functional theory calculations. Experimental and quantum-chemical data are analyzed jointly in terms of the previously recognized structure-formation laws in aqueous and nonaqueous solutions. The first low-toxicity cryoprotector is developed and tested. The structure and energy parameters of polymer chains are determined in three glass-forming compositions of the Mg(CH 3COO) 2–(CH 3) 2SO–H 2O system. The structure of these chains, which are built of magnesium hexasolvates linked via CH 3COO − ions and water molecules, is found to obey the structure formation laws that operate in solutions. Competition among (CH 3) 2SO, H 2O, and CH 3COO − species for entering the first coordination sphere of Mg 2+ is studied. The hydrogen-bonded crystallization-resistant glasses are found to differ from crystallization-liable glasses by higher specific linking strengths (referred to the unit weight) of polymer-chain units.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Material Dynamics and Properties · Thermal and Kinetic Analysis · Chemical Thermodynamics and Molecular Structure
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (49)
Show source-provided references
1. Revival of spermatozoa after vitrification and dehydration at low temperature10.1038/164666a0 ↗
2. Phase diagram for the system water–dimethyl sulphoxide10.1038/2201315a0 ↗
3. Cryoprotectants: a review of the actions and applications of cryoprotective solutes that modulate cell recovery from ultra-low temperatures10.1016/j.cryobiol.2017.04.004 ↗
4. A.A. Kostyaev, A.K. Martusevich, A.A. Andreev, Toxicity of cryoprotectants and cryoconservants on their basis for blood components and bone marrow (review article). Nauchnoe Obozrenie. Meditsinskie Nauki 6 (2016) 54–74. ISSN 2500-0780.
5. A.V. Zinchenko, E.N. Bobrova, Physical processes in cord blood plasma below 0° in the presence of 1, 2-propanediol, glycerol, and dimethyl sulfoxide, Dopov. Nats. Akad. Nauk Ukr. 12 (2010) 166–170. ISSN:1025-6415.
6. Computational screening of cryoprotective agents for regenerative medical products using quantum chemistry and molecular dynamics simulations10.1016/j.cryobiol.2021.03.002 ↗
7. Supercooling of aqueous dimethyl-sulfoxide solution at normal and high pressures: evidence for the coexistence of phase-separated aqueous dimethyl-sulfoxide solutions of different water structures10.1063/1.3429973 ↗
8. Supercooling and vitrification of aqueous glycerol solutions at normal and high pressures10.1016/j.cryobiol.2012.05.002 ↗
9. DMSO-free cryopreservation of human umbilical cord tissue10.1007/s10517-018-4305-5 ↗
10. Dimethyl-sulfoxide-free cryopreservation for cell therapy: a review
11. Concentration dependence of the cell membrane permeability to cryoprotectant and water and implications design of methods post-thaw washing of human erythrocytes10.1016/j.cryobiol.2017.12.003 ↗
12. Effect of different glycerol concentrations of phosphatidylserine translocation and mitochondrial membrane potential in chilled boar spermatozoa10.1016/j.cryobiol.2020.05.012 ↗
13. Controlled ice nucleation in cryopreservation—a review10.1016/j.cryobiol.2012.11.007 ↗
14. A study on cryoprotectant solution suitable for vitrification of rat two cell stage embryos10.1016/j.cryobiol.2014.01.011 ↗
15. Deglycerolization of red blood cells: a new dilution-filtration system10.1016/j.cryobiol.2018.01.006 ↗
16. The vitreous state10.1063/1.1749551 ↗
17. Kobeko · 1952
18. Rawson · 1967
19. Glass-forming composition regions and glass transition temperatures for aqueous electrolyte solutions10.1063/1.1673099 ↗
20. Liquid fragility and the glass transition in water and aqueous solutions10.1021/cr000689q ↗
21. Kirilenko · 2016
22. Theoretical and experimental studies in hydrogen-bonded glass-forming systems
23. Structural aspect of glass formation in aqueous electrolyte glass-forming systems10.1134/S0036023617140042 ↗
24. Water-electrolyte glass-forming systems: a review10.1134/S0036023618130053 ↗
25. Glass formation mechanism in aqueous formic acid solutions10.1016/j.jnoncrysol.2021.121130 ↗
26. Mechanism of the azeotropy phenomenon in aqueous formic acid solutions10.1134/S0036023620100204 ↗
27. Structure and regularities of formation of H-bonded complexes in aqueous and nonaqueous binary solutions10.3103/S1541308X2002017X ↗
28. Competition between H2O and CH3OH molecules in the formation of the simplest stable proton disolvates and their solvation in aqueous methanol solutions of KOH and CH3OK10.1134/S0022476617010103 ↗
29. Composition and structure of hydrates of CH3COOH molecules and CH3CO2− anions in aqueous solutions10.1134/S0022476617070125 ↗
30. Structure of complexes in the H2SO4-2-pyrrolidone system as determined by IR-spectroscopy and quantum-chemical calculations10.1134/S1990793117010080 ↗
31. Structure of complexes in HCl–isopropyl alcohol solutions and equilibrium composition of the system10.1134/S0022476621090055 ↗
32. Kirilenko · Russ. J. Inorg. Chem. · 2020 · 65 · 98910.1134/S003602362006008X ↗
33. A new method of the electrolyte-free long-term preservation of Human sperm at 4 °C10.1016/S0015-0282(16)58340-X ↗
34. Viability and function of human sperm in electrolyte-free cold preservation10.1016/S0015-0282(97)00439-1 ↗
35. Frezing – free preservation of human spermatozoa—a pilot study10.1080/01485010701569874 ↗
36. Short-term storage of human spermatozoa in electrolyte-free medium without freezing maintains chromatin integrity better than cryopresepvation10.1095/biolreprod.111.091322 ↗
37. Short - term liquid sperm storage in IVF/ICSI cycles10.17116/repro201521465-70 ↗
38. B.L. Zeller, R.C. Dinwoodie, A. Akashe, C.J. Baldwin, Amorphous water-soluble calcium citrate salts and method of making and using same as beverage supplements, Assignee: Kraft Foods Holdings, Inc., USA Patent No. US 20050181096 Date 18.08.2005.
39. K.K. Fuji, Co., Ltd, Japan—Horii Pharmaceutical Industries Ltd., Magnesium citrate powder for medical use, Patent № JP 55108814 A, Patent No. JP 57048528 B. Date 16.10.1982.
40. I.A. Kirilenko, V.P. Danilov, L.I. Demina, Method for obtaining amorphous water-soluble salts of magnesium citrate. Patent № RU 2756322 C120210929. Date 29.09.2021.
41. Glass formation in AlCl3–(CH3)2SO–H2O system10.1134/S0036023619100073 ↗
42. The glass formation in the Al2(SO4)3–(CH3)2SO–H2O system10.1134/S0036023618100108 ↗
43. H.Y. Abeyrathne, D.U. Lee, Egg white proteins and their potential use in food processing or as nutraceutical and pharmaceutical agents—a review /E.D.N.S. Ann// Poultry Science 92 (2013) 3292–3299.10.3382/ps.2013-03391 ↗
44. Quantitative analysis of gelation in egg protein systems
45. Frisch · 2009
46. Frisch · 2019
47. Sulfoxides as ligands. II. The infrared spectra of some dimethyl sulfoxide complexes10.1021/j100839a046 ↗
48. Cationic and neutral chloride complexes of palladium(II) with the nonaqueous solvent donors acetonitrile, dimethyl sulfoxide, and a series of amides. Mixed sulfur and oxygen coordination sites in a dimethyl sulfoxide complex10.1021/ic50074a050 ↗
49. Relationships between the carbon-oxygen stretching frequencies of carboxylate complexes and the type of carboxylate coordination10.1016/S0010-8545(00)80455-5 ↗