journal article·2017-07

Novel gallium-doped amorphous calcium phosphate nanoparticles: Preparation, application and structure study

Mingshun Yang, Jinjun Ren, Ruili Zhang

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Abstract

Abstract Novel gallium-doped amorphous calcium phosphate (ACP) nanoparticles with different (Ga + Ca)/P molar ratio (1.8–3.0) were synthesized using sol-gel method. The antibacterial effects of the gallium-doped ACP samples were tested using disk diffusion assays, against Pseudomonas aeruginosa . The results showed that the gallium-doped ACP samples have obvious effect of inhibiting the growth of Pseudomonas aeruginosa and could have a long term antibacterial properties. The local structures of these amorphous calcium phosphate nanoparticles were studied by 31 P, 71 Ga single pulse, double-resonance and 31 P homonuclear dipolar recoupling solid state NMR techniques. The solid state NMR studies indicate that gallium-doped ACP nanoparticles are consisted of Ga x (OH) y O z and calcium phosphate clusters. Gallium-doped ACP nanoparticles could be promising complex materials with the properties of antibacterial and biological mineralization.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Chemical Synthesis and Characterization · Luminescence Properties of Advanced Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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