Formation and properties of biocompatible Ti-based bulk metallic glasses in the Ti–Cu–Zr–Fe–Sn–Si–Ag system
Source abstract
Abstract
Abstract The Ni-free Ti-based bulk metallic glasses (BMGs) with high glass-forming ability (GFA) can be synthesized in the (Ti, Cu, Zr)92.5Fe2.5Sn2Si1Ag2 alloy system over a wide composition range by copper-mold casting. Especially, the Ti48Cu37Zr7.5Fe2.5Sn2Si1Ag2 glassy alloy can form the BMG rod with a diameter up to 6 mm and showed a high compressive strength of ~ 2.05 GPa, elastic modulus of ~ 100 GPa, and microhardness of ~ 571 Hv. The Ti-based BMGs presented good bio-corrosion resistance in a simulated physiological environment attributed to the formation of Ti-, Zr-, Si-, and Fe-enriched passive films. The biocompatibility of the Ti-based glassy alloys was systematically investigated by both indirect cytotoxicity test and direct cell-culture experiments. The Ti-based BMG extracts had no cytotoxic effects on the proliferation of the cells. The good cell adhesion, proliferation, differentiation, and mineralization of bone-forming MC3T3-E1 pre-osteoblasts on the BMGs were parallel to those on the Ti–6Al–4V alloy. These results manifested that the present Ti-based BMGs are promising candidates as biomaterials.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Metallic Glasses and Amorphous Alloys · Bone Tissue Engineering Materials · High Entropy Alloys Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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