Shape controlled quantum dot (QD)-decorated-mesoporous SiO2 (m-SiO2/QD) hollow particles for photodynamic therapy
Source abstract
Abstract
This work reported a novel kind of CdTe quantum dot (QD) decorated mesoporous SiO2 (m-SiO2/QD) hybrid hollow nanoparticles for carrying photodynamic therapy (PDT) reagent. Both rod-like and spherical nanoparticles were prepared by using different shaped templates. Due to the porous shell and hollow interior, the hybrid m-SiO2/QD hollow nanorod with 360 nm long and 120 nm in diameter was selected for carrying zinc(II) phthalocyanine (ZnPc) photosensitizing molecules (61 mg/g) since the generated reactive 1O2 could be easily delivered out of the hollow particles through the porous shell (BET area 251 cm2/g). It was found that the m-SiO2/QD-ZnPc hollow nanorods exhibited a good PDT activity and showed effective photocytotoxicity for the cancer cells. Because of the porous nature, fluorescence characteristic, and excellent storage ability, the m-SiO2/QD hybrid hollow particles possessed broad potential in the fluorescent labeled PDT.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Photocatalysis Techniques · Photodynamic Therapy Research Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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