journal article·2015-12

Composite nanoparticle of Au and quantum dots for X-ray computed tomography and fluorescence dual-mode imaging in vivo

Ji-Tao Song, Xiao-Quan Yang, Xiao-Shuai Zhang, Dong-Mei Yan, Ming-Hao Yao, Meng-Yao Qin, Yuan-Di Zhao

Journal of Nanoparticle Research· Volume 17· Issue 12
Publisher page

Abstract

In this study, composite nanoparticles comprising Au nanoparticle and quantum dots were built and used for contrast-enhanced computed tomography imaging (CT) and fluorescence dual-mode imaging in vivo. The nanoparticle exhibited good monodispersity and good biocompatibility, and had excellent CT contrast-enhancement effect and fluorescence imaging capability. They were appropriate for being used as dual-mode imaging probe in vivo.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Nanoparticle-Based Drug Delivery · Quantum Dots Synthesis And Properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (26)

Show source-provided references
1. Ai K, Liu Y, Liu J, Yuan Q, He Y, Lu L (2011) Large-scale synthesis of Bi2S3 nanodots as a contrast agent for in vivo X-ray computed tomography imaging. Adv Mater 23(42):4886–489110.1002/adma.201103289 ↗
2. Albanese A, Tang PS, Chan WCW (2012) The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng 14:1–1610.1146/annurev-bioeng-071811-150124 ↗
3. Bertrand N, Wu J, Xu X, Kamaly N, Farokhzad OC (2014) Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliver Rev 66:2–2510.1016/j.addr.2013.11.009 ↗
4. Chan Y, Zimmer JP, Troh MS, Steckel JS, Jain RK, Bawendi MG (2004) Incorporation of luminescent nanocrystals into monodisperse core-shell silica microspheres. Adv Mater 16(23–24):2092–209710.1002/adma.200400237 ↗
5. Cho WS, Cho M, Jeong J, Choi M, Han BS, Shin HS, Hong J, Chung BH, Jeong J, Cho MH (2010) Size-dependent tissue kinetics of PEG-coated gold nanoparticles. Toxicol Appl Pharmacol 245(1):116–12310.1016/j.taap.2010.02.013 ↗
6. Cole LE, Ross RD, Tilley JMR, Tracy VG, Ryan KR (2015) Gold nanoparticles as contrast agents in x-ray imaging and computed tomography. Nanomedicine 10(2):321–34110.2217/nnm.14.171 ↗
7. Danhier F, Feron O, Préat V (2010) To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J Control Release 148(2):135–14610.1016/j.jconrel.2010.08.027 ↗
8. Huang P, Bao L, Zhang C, Lin J, Luo T, Yang D, He M, Li Z, Gao G, Gao B, Fu S, Cui DX (2011) Folic acid-conjugated silica-modified gold nanorods for X-ray/CT imaging-guided dual-mode radiation and photo-thermal therapy. Biomaterials 32(36):9796–980910.1016/j.biomaterials.2011.08.086 ↗
9. Huang HH, Chen J, Meng YZ, Yang XQ, Zhang MZ, Yu Y, Ma ZY, Zhao YD (2013) Synthesis and characterization of Bi2S3 composite nanoparticles with high X-ray absorption. Mater Res Bull 48(10):3800–380410.1016/j.materresbull.2013.05.091 ↗
10. Kim D, Jeong YY, Jon S (2010) A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer. ACS Nano 4(7):3689–369610.1021/nn901877h ↗
11. Kobayashi Y, Inose H, Nakagawa T, Gonda K, Takeda M, Ohuchi N, Kasuyac A (2011) Control of shell thickness in silica-coating of Au nanoparticles and their X-ray imaging properties. J Colloid Interface Sci 358(2):329–33310.1016/j.jcis.2011.01.058 ↗
12. Kobayashi Y, Inose H, Nakagawa T, Gonda K (2013a) X-ray imaging technique using colloid solution of Au/silica core-shell nanoparticles. J Nanostruct Chem 3(1):1–6
13. Kobayashi Y, Inose H, Nagasu R, Nakagawa T, Kubota Y, Gonda K, Ohuchi N (2013b) X-ray imaging technique using colloid solution of Au silica poly (ethylene glycol) nanoparticles. Mater Res Innovations 17(7):507–51410.1179/1433075X13Y.0000000100 ↗
14. Li WP, Liao PY, Su CH, Yeh CS (2014) Formation of oligonucleotide-gated silica shell-coated Fe3O4-Au core-shell nanotrisoctahedra for magnetically targeted and near-infrared light-responsive theranostic platform. J Am Chem Soc 136(28):10062–1007510.1021/ja504118q ↗
15. Mebius RE, Kraal G (2005) Structure and function of the spleen. Nat Rev Immunol 5(8):606–61610.1038/nri1669 ↗
16. Moghimi SM (1995) Mechanisms of splenic clearance of blood cells and particles: towards development of new splenotropic agents. Adv Drug Delivery Rev 17(1):103–11510.1016/0169-409X(95)00043-7 ↗
17. Oh MH, Lee N, Kim H, Park SP, Piao Y, Lee J, Jun SW, Moon WK, Choi SH, Hyeon T (2011) Large-scale synthesis of bioinert tantalum oxide nanoparticles for X-ray computed tomography imaging and bimodal image-guided sentinel lymph node mapping. J Am Chem Soc 133(14):5508–551510.1021/ja200120k ↗
18. Popovtzer R, Agrawal A, Kotov NA, Popovtzer A, Balter J, Carey TE, Kopelman R (2008) Targeted gold nanoparticles enable molecular CT imaging of cancer. Nano Lett 8(12):4593–459610.1021/nl8029114 ↗
19. Qiu H, Cui B, Li G, Yang J, Peng H, Wang Y, Li N, Gao R, Chang Z, Wang Y (2014) Novel Fe3O4@ ZnO@ mSiO2 nanocarrier for targeted drug delivery and controllable release with microwave irradiation. J Phys Chem C 118(27):14929–1493710.1021/jp502820r ↗
20. Selvan ST, Patra PK, Ang CY, Ying JY (2007) Synthesis of silica-coated semiconductor and magnetic quantum dots and their use in the imaging of live cells. Angew Chem 119(14):2500–250410.1002/ange.200604245 ↗
21. Shilo M, Reuveni T, Motiei M, Popovtzer R (2012) Nanoparticles as computed tomography contrast agents: current status and future perspectives. Nanomedicine 7(2):257–26910.2217/nnm.11.190 ↗
22. Song JT, Yang XQ, Zhang XS, Yan DM, Yao MH, Qin MY, Zhao YD (2015) Composite silica coated gold nanosphere and quantum dots nanoparticles for X-ray CT and fluorescence bimodal imaging. Dalton Trans 44:11314–1132010.1039/C5DT01286D ↗
23. Sun Y, Feng W, Yang P, Huang C, Li F (2015) The biosafety of lanthanide upconversion nanomaterials. Chem Soc Rev 44(6):1509–152510.1039/C4CS00175C ↗
24. Xi D, Dong S, Meng X, Meng L, Ye J (2012) Gold nanoparticles as computerized tomography (CT) contrast agents. RSC Adv 2(33):12515–1252410.1039/c2ra21263c ↗
25. Yang XQ, Meng YZ, Luo QM, Gong H (2010) High resolution in vivo micro-CT with flat panel detector based on amorphous silicon. J X-Ray Sci Technol 18(4):38110.3233/XST-2010-0269 ↗
26. Yang XQ, Gong H, Fu JW, Quan GT, Huang C, Luo QM (2012) Molecular imaging of small animals with fluorescent proteins: from projection to multimodality. Comput Med Imag Grap 36(4):259–26310.1016/j.compmedimag.2011.09.002 ↗