journal article·2013-01

Size-dependent motion of bio-functionalized magnetic nanoparticle clusters under a rotating magnetic field

Ji-Ching Lai, Chia-Chun Tang, Chin-Yih Hong

Journal of Nanoparticle Research· Volume 15· Issue 1
Publisher page

Abstract

In this paper, we investigated the behavior of biofunctionalized, magnetic nanoparticle clusters under rotating magnetic fields in an aqueous solution to facilitate the use of such nanoparticles in biomedical applications. We found that two modes of motion for clusters of the nanoparticles exist. These two modes of motion exhibited by the clusters were rotation and oscillation, depending on the size of the cluster. Due to the interaction between the rotating magnetic field and the net magnetic dipole moment, the clusters were subjected to a forced vibration. A critical diameter range for the magnetic clusters was defined that may be used to distinguish between the rotation and oscillation of clusters. Furthermore, the characteristics of size dependence of the clusters’ motion were also investigated.
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Research context

OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Magnetic and Electromagnetic Effects · Microfluidic and Bio-sensing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (24)

Show source-provided references
1. Alexiou C, Arnold W, Klein RJ, Parak FG, Hulin P, Bergemann C, Erhardt W, Wagenpfeil S, Lübbe AS (2000) Locoregional cancer treatment with magnetic drug targeting. Cancer Res 60:6641–6684
2. Arruebo M, Fernandez-Pacheco R, Ibarra MR, Santamaria J (2007) Magnetic nanoparticles for drug delivery. Nano Today 2:22–3210.1016/S1748-0132(07)70084-1 ↗
3. Cēbers A, Javaitis I (2004) Bending of flexible magnetic rods. Phys. Rev. E 69:02140410.1103/PhysRevE.69.021404 ↗
4. Cēbers A, Ozols M (2006) Dynamics of an active magnetic particle in a rotating magnetic field. Phys Rev E 73:02150510.1103/PhysRevE.73.021505 ↗
5. Domínguez-García P, Melle S, Calderón OG, Rubio MA (2005) Doublet dynamics of magnetizable particles under frequency modulated rotating fields. Colloids Surf A 270:270–27110.1016/j.colsurfa.2005.06.012 ↗
6. Enpuku K, Minotani T, Hotta M, Nakahodo A (2001) Application of high Tc SQUID magnetometer to biological immunoassays. IEEE Trans Appl Supercon 11:661–66410.1109/77.919431 ↗
7. Enpuku K, Kuroda D, Ohba A, Yang TQ, Yoshinaga K, Nakahara T, Kuma H, Hamasaka N (2003) Biological immunoassay utilizing magnetic marker and high tc superconducting quantum interference device magnetometer. Jpn J Appl Phys 42:L1436–L143810.1143/JJAP.42.L1436 ↗
8. Enpuku K, Inoue K, SoeJima K, Yoshinaga K, Kuma H, Hamasaki N (2005) Magnetic immunoassays utilizing magnetic markers and a high-Tc SQUID. IEEE Trans Appl Supercond 15:660–66310.1109/TASC.2005.849991 ↗
9. Helgesen G, Pieranski P, Skjeltorp AT (1990a) Nonlinear phenomena in systems of magnetic holes. Phys Rev A 42:7271–728310.1103/PhysRevA.42.7271 ↗
10. Helgesen G, Pieranski P, Skjeltorp AT (1990b) Dynamic behavior of simple magnetic hole systems. Phys Rev Lett 64:1425–142910.1103/PhysRevLett.64.1425 ↗
11. Hong CY, Wu CC, Chiu YC, Yang SY, Horng HE, Yang HC (2006) Magnetic susceptibility reduction method for magnetically labeled immunoassay. Appl Phys Lett 88:21251210.1063/1.2206557 ↗
12. Horng HE, Yang SY, Hong CY, Liu CM, Tsai PS, Yang HC, Wu CC (2006) Biofunctionalized magnetic nanoparticles for high-sensitivity immunomagnetic detection of human C-reactive protein. Appl Phys Lett 88:25250610.1063/1.2207990 ↗
13. Ito A, Shinkai M, Honda H, Kobayashi T (2005) Medical application of functionalized magnetic nanoparticles. J Biosci Bioeng 100:1–1110.1263/jbb.100.1 ↗
14. Kötitz R, Matz H, Trahms L, Weitschies W, Rheinländer T, Semmler W, Bunte T (1997) SQUID based remanence measurements for immunoassays. IEEE Trans Appl Supercond 7:3678–368110.1109/77.622216 ↗
15. Lee SK, Myers WR, Grossmanl HL, Cho HM, Chemla YR, Clarke J (2002) Magnetic gradiometer based on a high-transition temperature superconducting quantum interference device for improved sensitivity of a biosensor. Appl Phys Lett 81:3094–309710.1063/1.1515122 ↗
16. Melle S, Calderón OG, Fuller GG, Rubio MA (2002) Polarizable particle aggregation under rotating magnetic fields using scattering dichroism. J Colloid Interface Sci 247:200–20910.1006/jcis.2001.8087 ↗
17. Pankhurst QA, Connolly J, Jones SK, Dobson J (2003) Applications of magnetic nanoparticles in biomedicine. J Phys D 36:R167–R18110.1088/0022-3727/36/13/201 ↗
18. Ruehm SG, Corot C, Vogt P, Kolb S, Debatin JF (2001) Magnetic resonance imaging of atherosclerotic plaque with ultra small super paramagnetic particles of iron oxide in hyperlipidemic rabbits. Circulation 103:415–42210.1161/01.CIR.103.3.415 ↗
19. Tartaj P, Morales MDP, Veintemillas-Verdaguer S, González-Carreño T, Serna CJ (2003) The preparation of magnetic nanoparticles for applications in biomedicine Phys. D-Appl Phys 36:R182–R19710.1088/0022-3727/36/13/202 ↗
20. Todd P, Cooper RP, Doyle JF, Dunn S, Vellinger J, Deuser MS (2001) Multistage magnetic particle separator. J Magn Magn Mater 225:294–30010.1016/S0304-8853(00)01253-1 ↗
21. Weitschies W, Kötitz R, Bunte T, Trahms L (1997) Determination of relaxing or remanent nanoparticle magnetization provides a novel binding-specific technique for the evaluation of immunoassays. Pharm Pharmacol Lett 7:1–7
22. Wust P, Hildebrandt B, Sreenivasa G, Rau B, Gellermann J, Riess H, Felix R, Schlag PM (2002) Hyperthermia in combined treatment of cancer. The Lancet Oncol 3:487–49710.1016/S1470-2045(02)00818-5 ↗
23. Yang SY, Wang WC, Lan CB, Chen CH, Chieh JJ, Horng HE, Hong CY, Yang HC, Tsai CP, Yang CY (2010) Magnetically enhanced high-specificity virus detection using bio-activated magnetic nanoparticles with antibodies as labeling markers. J Virol Methods 164:14–1810.1016/j.jviromet.2009.11.016 ↗
24. Zhao M, Beauregard DA, Loizoul L, Davletov B, Brindle KM (2001) Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent. Nat Med 7:1241–124410.1038/nm1101-1241 ↗