TEM Imaging of Mass-selected Polymer Molecules
Source abstract
Abstract
Polyethylene glycol (PEG) molecules with masses below 1300 amu are electrosprayed (ES) from solution, mobility-selected at high resolution in a differential mobility analyzer (DMA), collected on a grid and imaged by transmission electron microscopy (ES–DMA–TEM). The DMA resolves individual n-mers, and selects only one out of the many present in the original sample. Ion identity is established from parallel mass spectra (ES-MS). The images reveal spherical particles 1.46 nm in diameter, in good agreement with the known ion mass and bulk density. The DMA-selection technique opens new paths for the study of very small particles.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Mass Spectrometry Techniques and Applications · Ion-surface interactions and analysis · Analytical Chemistry and Chromatography
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