A critical evaluation of the safety datasheets of graphene materials
Source abstract
Abstract
Abstract Graphene, a single layer of carbon atoms, is a material that has held a leading position in material research owing to its excellent properties, allowing its use in innovative technologies. In spite of many advantages, the graphene’s potentially hazardous effect on the environment as well as human health constitutes a major drawback. Year after year, safety data sheets (SDS) constitute the main reference on a material’s potential hazards and the methods to prevent or address them if needed. However, SDS content has been heavily criticized due to incomplete, incorrect, or missing information and the cost required to produce and maintain it. The primary objective of this work is to introduce a stepwise process of knowledge management regarding SDSs, by identifying unexplored or neglected sections in a holistic approach. In this light, this work examines 37 graphene SDS, using modified Hodson’s criteria. The quality evaluation revealed that approximately 5% (2/37) of the datasheets were deemed reliable without restrictions (excellent), the majority 49% (18/37) were categorized as reliable with restrictions (good), while about reaching almost 46% (17/37) were deemed non-informative. It is noteworthy that approximately 73% of the SDS require major improvements; thus, the majority did not provide adequate data to be properly assessed. Section 15 could potentially trigger fundamental changes in the product status. The comprehensive evaluation of all 16 sections will enhance the capacity to conduct research mapping and formulate opinions on nanomaterials, thereby stimulating innovation.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Risk and Safety Analysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (38)
Show source-provided references
1. Miyazaki K, Islam N (2007) Nanotechnology systems of innovation—an analysis of industry and academia research activities. Technovation 27:661–675. https://doi.org/10.1016/j.technovation.2007.05.00910.1016/j.technovation.2007.05.009 ↗
2. Rambaran T, Schirhagl R (2022) Nanotechnology from lab to industry – a look at current trends. Nanoscale Adv 4:3664–3675. https://doi.org/10.1039/D2NA00439A10.1039/D2NA00439A ↗
3. Tiwari SK, Sahoo S, Wang N, Huczko A (2020) Graphene research and their outputs: status and prospect. J Sci Adv Mater Dev 5:10–29. https://doi.org/10.1016/j.jsamd.2020.01.00610.1016/j.jsamd.2020.01.006 ↗
4. Tiwari SK, Kumar V, Huczko A, Oraon R, Adhikari AD, Nayak GC (2016) Magical allotropes of carbon: prospects and applications. Crit Rev Solid State Mater Sci 41:257–317. https://doi.org/10.1080/10408436.2015.112720610.1080/10408436.2015.1127206 ↗
5. Tiwari SK, Mishra RK, Ha SK, Huczko A (2018) Evolution of graphene oxide and graphene: from imagination to industrialization. Chem Nano Mat 4:598–620. https://doi.org/10.1002/cnma.20180008910.1002/cnma.201800089 ↗
6. Yang Y, Liu R, Wu J, Jiang X, Cao P, Hu X, Pan T, Qiu C, Yang J, Song Y et al (2015) Bottom-up fabrication of graphene on silicon/silica substrate via a facile soft-hard template approach. Sci Rep 5:13480. https://doi.org/10.1038/srep1348010.1038/srep13480 ↗
7. Bahadır EB, Sezgintürk MK (2016) Applications of graphene in electrochemical sensing and biosensing. TrAC, Trends Anal Chem 76:1–14. https://doi.org/10.1016/j.trac.2015.07.00810.1016/j.trac.2015.07.008 ↗
8. Sarma S, Ray SC, Strydom AM (2017) Electronic and magnetic properties of nitrogen functionalized graphene-oxide. Diam Relat Mater 79:1–6. https://doi.org/10.1016/j.diamond.2017.08.01110.1016/j.diamond.2017.08.011 ↗
9. Papageorgiou DG, Kinloch IA, Young RJ (2017) Mechanical properties of graphene and graphene-based nanocomposites. Prog Mater Sci 90:75–127. https://doi.org/10.1016/j.pmatsci.2017.07.00410.1016/j.pmatsci.2017.07.004 ↗
10. Zhong Y, Zhen Z, Zhu H (2017) Graphene: fundamental research and potential applications. FlatChem 4:20–32. https://doi.org/10.1016/j.flatc.2017.06.00810.1016/j.flatc.2017.06.008 ↗
11. Schöche S, Hong N, Khorasaninejad M, Ambrosio A, Orabona E, Maddalena P, Capasso F (2017) Optical properties of graphene oxide and reduced graphene oxide determined by spectroscopic ellipsometry. Appl Surf Sci 421:778–782. https://doi.org/10.1016/j.apsusc.2017.01.03510.1016/j.apsusc.2017.01.035 ↗
12. Kyzas GZ, Deliyanni EA, Matis KA (2014) Graphene oxide and its application as an adsorbent for wastewater treatment: graphene oxide as adsorbent in wastewater treatment. J Chem Technol Biotechnol 89:196–205. https://doi.org/10.1002/jctb.422010.1002/jctb.4220 ↗
13. Pelin M, Sosa S, Prato M, Tubaro A (2018) Occupational exposure to graphene based nanomaterials: risk assessment. Nanoscale 10:15894–15903. https://doi.org/10.1039/C8NR04950E10.1039/C8NR04950E ↗
14. DeMasi A, Elston H, Langerman N (2022) Safety data sheets: challenges for authors, expectations for end-users. ACS Chem Health Saf 29:369–377. https://doi.org/10.1021/acs.chas.2c0001510.1021/acs.chas.2c00015 ↗
15. Nanotechnology environmental health and safety Elsevier, (2018) ISBN 978–0–12–813588–4
16. Kingsley WK (2000) Knowledge is power Chem Health Saf 7:50–50. https://doi.org/10.1016/S1074-9098(00)00065-410.1016/S1074-9098(00)00065-4 ↗
17. Jonai H (2021) Impact of the GHS on chemical management in Japan. ACS Chem Health Saf 28:320–325. https://doi.org/10.1021/acs.chas.1c0003210.1021/acs.chas.1c00032 ↗
18. Eastlake A, Hodson L, Geraci C, Crawford C (2012) A critical evaluation of material safety data sheets (MSDSs) for engineered nanomaterials. J Chem Health Saf 19:1–8. https://doi.org/10.1016/j.jchas.2012.02.00210.1016/j.jchas.2012.02.002 ↗
19. Nayar GA, Wehrmeyer W, Phillips CA, Crankshaw N, Marsh N, France C (2016) The efficacy of safety data sheets in informing risk based decision making: a review of the aerospace sector. J Chem Health Saf 23:19–29. https://doi.org/10.1016/j.jchas.2015.09.00210.1016/j.jchas.2015.09.002 ↗
20. Hodson L, Eastlake A, Herbers R (2019) An evaluation of engineered nanomaterial safety data sheets for safety and health information post implementation of the revised hazard communication standard. J Chem Health Saf 26:12–18. https://doi.org/10.1016/j.jchas.2018.10.00210.1016/j.jchas.2018.10.002 ↗
21. Boverhof DR, Bramante CM, Butala JH, Clancy SF, Lafranconi M, West J, Gordon SC (2015) Comparative assessment of nanomaterial definitions and safety evaluation considerations. Regul Toxicol Pharmacol 73:137–150. https://doi.org/10.1016/j.yrtph.2015.06.00110.1016/j.yrtph.2015.06.001 ↗
22. Engeman CD, Baumgartner L, Carr BM, Fish AM, Meyerhofer JD, Satterfield TA, Holden PA, Harthorn BH (2013) The hierarchy of environmental health and safety practices in the U.S. nanotechnology workplace. J Occup Environ Hyg 10:487–495. https://doi.org/10.1080/15459624.2013.81823110.1080/15459624.2013.818231 ↗
23. Geraci C, Heidel D, Sayes C, Hodson L, Schulte P, Eastlake A, Brenner S (2015) Perspectives on the design of safer nanomaterials and manufacturing processes. J Nanopart Res 17:366. https://doi.org/10.1007/s11051-015-3152-910.1007/s11051-015-3152-9 ↗
24. Kim J, Yu IJ (2016) National survey of workplaces handling and manufacturing nanomaterials, exposure to and health effects of nanomaterials, and evaluation of nanomaterial safety data sheets. Biomed Res Int 2016:1–10. https://doi.org/10.1155/2016/838912910.1155/2016/8389129 ↗
25. Lee JH, Kuk WK, Kwon M, Lee JH, Lee KS, Yu IJ (2012) Evaluation of information in nanomaterial safety data sheets and development of international standard for guidance on preparation of nanomaterial safety data sheets. Nanotoxicology 7:338–345. https://doi.org/10.3109/17435390.2012.65809510.3109/17435390.2012.658095 ↗
26. Schimpel C, Resch S, Flament G, Carlander D, Vaquero C, Bustero I, Falk A (2018) A methodology on how to create a real-life relevant risk profile for a given nanomaterial. J Chem Health Saf 25:12–23. https://doi.org/10.1016/j.jchas.2017.06.00210.1016/j.jchas.2017.06.002 ↗
27. Amyotte, P.R. (2019) Methods in chemical process safety: dust explosions; Methods in chemical process safety; Elsevier: Cambridge, Massachusetts, ISBN 978–0–12–817550–7
28. Grieger K, Jones JL, Hansen SF, Hendren CO, Jensen KA, Kuzma J, Baun A (2019) best practices from nano-risk analysis relevant for other emerging technologies. Nat Nanotechnol 14:998–1001. https://doi.org/10.1038/s41565-019-0572-110.1038/s41565-019-0572-1 ↗
29. Teunenbroek TV, Baker J, Dijkzeul A (2017) Towards a more effective and efficient governance and regulation of nanomaterials. Part Fibre Toxicol 14:54. https://doi.org/10.1186/s12989-017-0235-z10.1186/s12989-017-0235-z ↗
30. The handbook of nanotechnology: business, policy, and intellectual property law; Miller, J.C., Ed.; John Wiley & Sons: Hoboken, N.J, (2005) ISBN 978–0–471–66695–0
31. Handy ROAR (2007) Viewpoint: formulating the problems for environmental risk assessment of nanomaterials. Environ Sci Technol 41:5582–5588. https://doi.org/10.1021/es072598h10.1021/es072598h ↗
32. Choi J-Y, Ramachandran G, Kandlikar M (2009) The impact of toxicity testing costs on nanomaterial regulation. Environ Sci Technol 43:3030–3034. https://doi.org/10.1021/es802388s10.1021/es802388s ↗
33. Tóth AJ, Fózer D, Mizsey P, Varbanov PS, Klemeš JJ (2022) Physicochemical methods for process wastewater treatment: powerful tools for circular economy in the chemical industry. Reviews in Chemical Engineering 0 https://doi.org/10.1515/revce-2021-009410.1515/revce-2021-0094 ↗
34. Klimisch H-J, Andreae M, Tillmann U (1997) A Systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data. Regul Toxicol Pharmacol 25:1–5. https://doi.org/10.1006/rtph.1996.107610.1006/rtph.1996.1076 ↗
35. Jeevanandam J, Krishnan S, Hii YS, Pan S, Chan YS, Acquah C, Danquah MK, Rodrigues J (2022) Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocomposites. J Nanostruct Chem 12:809–831. https://doi.org/10.1007/s40097-021-00465-y10.1007/s40097-021-00465-y ↗
36. Chandrakala V, Aruna V, Angajala G (2022) Review on metal nanoparticles as nanocarriers: current challenges and perspectives in drug delivery systems. Emergent Mater 5:1593–1615. https://doi.org/10.1007/s42247-021-00335-x10.1007/s42247-021-00335-x ↗
37. Loosli F, Rasmussen K, Rauscher H, Cross RK, Bossa N, Peijnenburg W, Arts J, Matzke M, Svendsen C, Spurgeon D et al (2022) Refinement of the selection of physicochemical properties for grouping and read-across of nanoforms. NanoImpact, 25 100375 https://doi.org/10.1016/j.impact.2021.10037510.1016/j.impact.2021.100375 ↗
38. Kolchinski AG (2022) When safety data sheets are a safety hazard. Org Process Res Dev 26:263–266. https://doi.org/10.1021/acs.oprd.1c0042710.1021/acs.oprd.1c00427 ↗