Carbon dots and gold nanocluster–based hybrid microgels and their application in cells imaging
Source abstract
Abstract
The hybrid microgels of carbon dots (CDs) and gold nanoclusters (AuNCs) have been prepared with precipitation polymerization. This hybrid microgels exhibited dual emissions thanks to organic integration of CDs and AuNCs for their unique fluorescence properties maintained in the microgel system. The fluorescence intensity ratio at 570 nm and 450 nm of the dual-emitting has a good linear response to temperature varying at the range of 20–50 °C. In addition, the ratio of the dual emissions intensity of the hybrid microgel shows well linear relationship at pH range between 9.0 and 11.0, which promises to be used as pH sensor. Furthermore, this hybrid microgel is inherently non-cytotoxic, which could be used as high efficient fluorescent probes in living cell with dual colors. Thus, this novel dual-emission hybrid microgel system can be used not only as a multifunctional sensor, but also to expand potential applications in biomedical engineering.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Carbon and Quantum Dots Applications · Nanocluster Synthesis and Applications · Advanced Nanomaterials in Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (22)
Show source-provided references
1. Sun YP, Zhou B, Lin Y, Wang W, Shiral FKA, Pathak P (2006) Quantum-sized carbon dots for bright and colorful photoluminescence. J Am Chem Soc 128:7756–7757. https://doi.org/10.1021/ja062677d10.1021/ja062677d ↗
2. Liao B, Long P, He BQ, Yi SJ, Ou BL, Shen SH, Chen J (2013) Reversible fluorescence modulation of spiropyran-functionalized carbon nanoparticles. J Mater Chem C 1:3716–3721. https://doi.org/10.1039/C3TC00906H10.1039/C3TC00906H ↗
3. Liao B, Wang W, Long P, Deng XT, He BQ, Liu QQ, Yi SJ (2015) The carbon nanoparticles grafted with copolymers of styrene and spiropyran with reversibly photoswitchable fluorescence. Carbon 91:30–37. https://doi.org/10.1016/j.carbon.2015.04.03010.1016/j.carbon.2015.04.030 ↗
4. Wang XL, Cheng ZL, Zhou Y (2020) A double carbon dot system composed of N, Cl-doped carbon dots and N, Cu-doped carbon dots as peroxidase mimics and as fluorescent probes for the determination of hydroquinone by fluorescence. Microchim Acta 187:350–358. https://doi.org/10.1007/s00604-020-04322-710.1007/s00604-020-04322-7 ↗
5. Wei J, Gao J, Liu Y et al (2019) Rapid preparation of homogeneous carbon dots with yellow fluorescence and formation mechanistic investigation. J Nanopart Res 21:74. https://doi.org/10.1007/s11051-019-4510-910.1007/s11051-019-4510-9 ↗
6. Wei XJ, Li L, Liu JL, Yu LD (2019) Green synthesis of fluorescent carbon dots from gynostemma for bioimaging and antioxidant in zebrafish. ACS Appl Mater Interfaces 10:9832–9840. https://doi.org/10.1021/acsami.9b0007410.1021/acsami.9b00074 ↗
7. Feng ZX, Adolfsson KH, Xu YA (2021) Carbon dot/polymer nanocomposites: from green synthesis to energy, environmental and biomedical applications. Sus Mater Tech 29:304–329. https://doi.org/10.1016/j.susmat.2021.e0030410.1016/j.susmat.2021.e00304 ↗
8. Javed N, Ocarroll DM (2021) Carbon dots and stability of their optical properties. Part Syst Charact 38:2000271–2000283. https://doi.org/10.1002/ppsc.20200027110.1002/ppsc.202000271 ↗
9. Shao Y, Zhu C, Fu Z et al (2020) Green synthesis of multifunctional fluorescent carbon dots from mulberry leaves (Morus alba L) residues for simultaneous intracellular imaging and drug delivery. J Nanopart Res 22:229. https://doi.org/10.1007/s11051-020-04917-410.1007/s11051-020-04917-4 ↗
10. Stefanakis D, Philippidis A, Sygellou L et al (2014) Synthesis of fluorescent carbon dots by a microwave heating process: structural characterization and cell imaging applications. J Nanopart Res 16:2646. https://doi.org/10.1007/s11051-014-2646-110.1007/s11051-014-2646-1 ↗
11. Zhang XC, Liu WJ, Gai QX, Tian ZS (2019) A carbon-dot based fluorescent probes for the sensitive and selective detection of copper(II) ions. Chem Select 4:2392–2397. https://doi.org/10.1002/slct.20180358410.1002/slct.201803584 ↗
12. Liang C, Hu X, Wang Y et al (2021) Study on luminescence mechanism of nitrogen-doped carbon quantum dots with different fluorescence properties and application in Fe3+ detection. J Nanopart Res 23:101. https://doi.org/10.1007/s11051-021-05208-210.1007/s11051-021-05208-2 ↗
13. Pramank G, Humpolickova J, Valenta J (2018) Gold nanoclusters with bright near-infrared photoluminescence. Nanoscale 8:3792–3798. https://doi.org/10.1039/c7nr06050e10.1039/c7nr06050e ↗
14. Suo ZG, Hou XL, Hu ZH (2019) Fibrinogen-templated gold nanoclusters for fluorometric determination of cysteine and mercury. Microchim Acta 186:799–808. https://doi.org/10.1007/s00604-019-3919-210.1007/s00604-019-3919-2 ↗
15. Gorbachevskii MV, Stavitskaya AV, Novikov AA (2017) Fluorescent gold nanoclusters stabilized on halloysite nanotubes: in vitro study on cytotoxicity. Appl Clay Sci 207:106106–106113. https://doi.org/10.1016/j.clay.2021.10610610.1016/j.clay.2021.106106 ↗
16. Yang DQ, Luo MC, Di JW, Tu YF (2018) Gold nanocluster-based ratiometric fluorescent probes for hydrogen peroxide and enzymatic sensing of uric acid. Microchim Acta 182:305–312. https://doi.org/10.1007/s00604-018-2823-510.1007/s00604-018-2823-5 ↗
17. Zhang YY, Jiang H, Wang XD (2015) Cytidine-stabilized gold nanocluster as a fluorescence turn-on and turn-off probe for dual functional detection of Ag+ and Hg2+. Anal Chim Acta 870:1–7. https://doi.org/10.1016/j.aca.2015.01.01610.1016/j.aca.2015.01.016 ↗
18. Eydelnant IA, Li BB, Wheeler AR (2014) Microgels on-demand. Nature Comm 5:3355–3364. https://doi.org/10.1038/ncomms435510.1038/ncomms4355 ↗
19. Suhal M, Li XR, Liu JY, Hsieh WC (2021) Fabrication of alginate based microgels for drug-sustained release: in-vitro and in-vivo evaluation. Inter J Bio Mac 192:958–966. https://doi.org/10.1016/j.ijbiomac.2021.10.05410.1016/j.ijbiomac.2021.10.054 ↗
20. Lu HZ, Xu SF (2017) Visualizing BPA by molecularly imprinted ratiometric fluorescence sensor based on dual emission nanoparticles. Biosens Bioelectron 92:147–153. https://doi.org/10.1016/j.bios.2017.02.01310.1016/j.bios.2017.02.013 ↗
21. Wang CX, Lin HH, Xu ZZ, Huang YJ, Humphrey MG, Zhang C (2016) Tunable carbon-dot-based dual-emission fluorescent nanohybrids for ratiometric optical thermometry in living cells. ACS Appl Mater Interfaces 8:6621–6628. https://doi.org/10.1021/acsami.5b1131710.1021/acsami.5b11317 ↗
22. Shang L, Stockmar F, Azadfar N, Nienhaus GU (2013) Intracellular thermometry by using fluorescent gold nanoclusters. Angew Chem Int Ed 52:11154–11157. https://doi.org/10.1002/anie.20130636610.1002/anie.201306366 ↗