DataVXJournal of Nanoparticle ResearchPaper
journal article·2023-07

Microneedles for delivery of anticancer therapeutics: recent trends and technologies

Prinsy Rana, Asmita Deka Dey, Tarun Agarwal, Arun Kumar

Journal of Nanoparticle Research· Volume 25· Issue 7
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Source abstract

Abstract

Cancer tops the list of most life-threatening diseases worldwide, recording around 10 million deaths annually. Implementation of microneedles (MNs) as a therapeutic delivery vehicle has revolutionized anticancer therapy, thanks to MNs’ minimally invasive and painless delivery aspect, high therapeutic efficacy, low cost, and relative biosafety. In this review, we overview the application of MNs for the delivery of different anticancer therapeutic and diagnostic modalities, including drugs, peptides, antibodies, gene, and vaccines. We further highlighted the fabrication strategies, materials, and therapeutic release patterns from MNs. Finally, we discussed biosafety concerns, translational aspects, limitations, and future perspective of MNs as an efficient anticancer theranostic system. Graphical Abstract
Source: expertdata · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Advancements in Transdermal Drug Delivery · Toxin Mechanisms and Immunotoxins · Immunotherapy and Immune Responses

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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