Synthesis of Eu(III): naphtoyltrifluoroacetone:trioctylphosphineoxide complex-doped silica fluorescent nanoparticles through a new approach
Source abstract
Abstract
In this study, a new approach for the preparation of a fluorescent europium(III) complex-doped silica nanoparticles has been developed. The synthesis process involved the following steps: (1) preparing silica nanoparticles by water-in-oil microemulsion method, (2) dyeing the spherical silica particles by europium(III): naphtoyltrifluoroacetone (NTA):trioctylphosphineoxide (TOPO), (3) adsorbing polyvinylpyrrolidone (PVP) onto the core structure and growing silica on PVP surface. The as-prepared nanoparticles exhibited stronger emission intensity, higher photo- and chemical stability. Despite the fact that europium(III) complex was doped into the nanoparticles, its fluorescence properties such as a wide Stokes shift, a narrow emission peak, and long fluorescence lifetime, were retained. The nanoparticles are uniform in shape and size (50 ± 5 nm in diameter). This study could provide new avenue for the fabrication of Eu: NTA:TOPO-based nanoparticles, facilitating their application in bioassay issues.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Lanthanide and Transition Metal Complexes · Radioactive element chemistry and processing · Polyoxometalates: Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (17)
Show source-provided references
1. Bagwe RP, Yang CY, Hilliard LR, Tan WH (2004) Optimization of dye-doped silica nanoparticles prepared using a reverse microemulsion method. Langmuir 20:8336–8342. doi: 10.1021/la049137j10.1021/la049137j ↗
2. Chinthamanipeta PS, Kobukata S, Nakata H, Shipp DA (2008) Synthesis of poly(methyl methacrylate)-silica nanocomposites using methacrylate-functionalized silica nanoparticles and RAFT polymerization. Polymer 26:5636–5642. doi: 10.1016/j.polymer.2008.10.01810.1016/j.polymer.2008.10.018 ↗
3. Daniel MC, Astruc D (2004) Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology. Chem Rev 1:293–346. doi: 10.1021/cr03069810.1021/cr030698+ ↗
4. Hanaoka K, Kikuchi K, Kobayashi S, Nagano T (2007) Time-Resolved long-lived luminescence imaging method employing luminescent lanthanide probes with a new microscopy system. J Am Chem Soc 129:13502–13509. doi: 10.1021/ja073392j10.1021/ja073392j ↗
5. Härmä H, Keranen AM, Lovgren T (2007) Synthesis and characterization of europium(III) nanoparticles for time-resolved fluoroimmunoassay of prostate specific antigen. Nanotechnology 18:5604–5610. doi: 10.1088/095710.1088/0957-4484/18/7/075604 ↗
6. Härmä H, Graf C, Hanninen P (2008) Synthesis and characterization of core-shell europium(III)-silica nanoparticle. J Nanopart Res 10:1221–1224. doi: 10.1007/s11051.008.9380.510.1007/s11051-008-9380-5 ↗
7. Henry AC, Tutt TJ, Galloway M (2000) Surface modification of poly(methyl methacrylate) used in the fabrication of microanalytical devices. Anal Chem 72:5331–5337. doi: 10.1021/ac000685110.1021/ac000685l ↗
8. Huhtinen P, Vaarno J, Soukka T, Lovgren T, Harma H (2004) Europium(III) nanoparticle-label-based assay for the detection of nucleic acids. Nanotechnology 15:1708–1715. doi: 10.1088/095710.1088/0957-4484/15/12/002 ↗
9. Huhtinen P, Kivela M, Kuronen O, Hagren V, Takalo H, Tenhu H, Lovgren T, Harma H (2005) Synthesis, characterization, and application of Eu(III), Tb(III), Sm(III), and Dy(III) lanthanide complex nanoparticle labels. Anal Chem 77:2643–2648. doi: 10.1021/ac048360i10.1021/ac048360i ↗
10. Lian W, Litherland SA, Badrane H, Tan WH, Wu DH, Baker HV, Gulig PA, Lim DV, Jin SG (2004) Ultrasensitive detection of biomolecules with fluorescent dye-doped nanoparticles. Anal Biochem 334:135–144. doi: 10.1016/j.ab.2004.08.00510.1016/j.ab.2004.08.005 ↗
11. Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S (2005) Quantum dots for live cells, in vivo image, and diagnostics. Science 307:538–544. doi: 10.1126/science.110427410.1126/science.1104274 ↗
12. Santra S, Zhang P, Wang KM, Tapec R, Tan WH (2001) Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Anal Chem 73:4933–4988. doi: 10.1021/ac01040610.1021/ac010406+ ↗
13. Tan MQ, Wang GL, Hai XD, Ye ZQ (2004) Development of functionalized fluorescent europium nanoparticles for biolabeling and time-resolved fluorometric applications. J Mater Chem 16:2896–2901. doi: 10.1039/b407535h10.1039/b407535h ↗
14. Wang L, Yang CY, Tan WH (2005) Dual-luminophore-doped silica nanoparticles for multiplexed signaling. Nano Lett 5:37–43. doi: 10.1021/nl048417g10.1021/nl048417g ↗
15. Ye ZQ, Tan MQ, Wang GL, Yuan JL (2004) Preparation, characterization, and time-resolved fluorometric application of silica-coated terbium(III) fluorescent nanoparticles. Anal Chem 76:513–518. doi: 10.1021/ac030177m10.1021/ac030177m ↗
16. Yin DG, Liu BH, Zhang L (2010) Preparation of fluorescent nanoparticle Ru(bpy)3/SiO2 and its application in protein microarray for HIV p24 detection. Chinese J Anal Chem 38:1095–1099. doi: 10.3724/SP.J.1096.2010.01095
17. Zhang H, Xu Y, Yang W, Li QG (2007) Dual-lanthanide-complexed silica nanoparticles as labels for highly sensitive time-resolved fluorometry. Chem Mater 19:5875–5881. doi: 10.1021/cm070900f10.1021/cm070900f ↗