Nanocrystalline magnesium oxide: an efficient promoter and heterogeneous nano catalyst for the one-pot synthesis of pyrazolotriazoles in green medium
Source abstract
Abstract
A simple, efficient, and relatively clean method for the synthesis of pyrazolo[1,2-a][1,2,4]triazole derivatives via a one-pot three-component reaction of aromatic aldehydes, 4-phenyl-1,2,4-triazolidine-3,5-dione, and malononitrile or alkyl cyanoacetates in the presence of a catalytic amount of nanocrystalline (NC) magnesium oxide has been developed. This method has several advantages such as, high to excellent product yields, reusability of catalyst, and simple work-up procedure in the nontoxic medium.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Multicomponent Synthesis of Heterocycles · Microwave-Assisted Synthesis and Applications · Synthesis and biological activity
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