journal article·2016-12Open access

Effect of silver/copper and copper oxide nanoparticle powder on growth of Gram-negative and Gram-positive bacteria and their toxicity against the normal human dermal fibroblasts

Jerzy Peszke, Anna Nowak, Jacek Szade, Agnieszka Szurko, Dorota Zygadło, Marlena Michałowska, Paweł Krzyściak, Patrycja Zygoń, Alicja Ratuszna, Marek M. Ostafin

Journal of Nanoparticle Research· Volume 18· Issue 12

Abstract

Engineered nanomaterials, especially metallic nanoparticles, are the most popular system applied in daily life products. The study of their biological and toxicity properties seems to be indispensable. In this paper, we present results of biological activity of Ag/Cu nanoparticles. These nanoparticles show more promising killing/inhibiting properties on Gram-negative bacteria than for Gram-positive ones. The Gram-negative bacteria show strong effect already at the concentration of 1 ppm after 15 min of incubation. Moreover, in vitro tests of toxicity made on normal human dermal fibroblast cultures showed that after 72 h of incubation with Ag/Cu nanoparticles, they are less toxic then Cu2O/CuO nanoparticles.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Nanoparticles: synthesis and applications · Graphene and Nanomaterials Applications · Laser-Ablation Synthesis of Nanoparticles

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (39)

Show source-provided references
1. Bernard V, Zobač O, Sopoušek J, Mornstein V (2014) AgCu bimetallic nanoparticles under effect of low intensity ultrasound: the cell viability study in vitro. Journal of Cancer Research 2014:1–6. doi: 10.1155/2014/97176910.1155/2014/971769 ↗
2. Calero MMS, Gutiérrez LPD, Salas GPD et al (2014) Efficient and safe internalization of magnetic iron oxide nanoparticles: two fundamental requirements for biomedical applications. Nanomedicine: Nanotechnology, Biology, and Medicine 10:733–743. doi: 10.1016/j.nano.2013.11.01010.1016/j.nano.2013.11.010 ↗
3. Chen S, Guo Y, Chen S et al (2012) Fabrication of Cu/TiO2 nanocomposite: toward an enhanced antibacterial performance in the absence of light. Mater Lett 83:154–157. doi: 10.1016/j.matlet.2012.06.00710.1016/j.matlet.2012.06.007 ↗
4. Czaplinska J, Sobczak I, Ziolek M (2014) Bimetallic AgCu/SBA-15 system: the effect of metal loading and treatment of catalyst on surface properties. J Phys Chem C 118:12796–12810. doi: 10.1021/jp501176410.1021/jp5011764 ↗
5. Feng QL, Wu J, Chen GQ et al (2000) A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. Journal of Biological Material Research 52:662–66810.1002/1097-4636(20001215)52:4<662::AID-JBM10>3.0.CO;2-3 ↗
6. Goetz von N, Lorenz C, Windler L et al (2013) Migration of Ag- and TiO 2-(Nano)particles from textiles into artificial sweat under physical stress: experiments and exposure modeling. Environ Sci Technol 47:9979–9987. doi: 10.1021/es304329w10.1021/es304329w ↗
7. Gupta AK, Gupta M (2005) Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26:3995–4021. doi: 10.1016/j.biomaterials.2004.10.01210.1016/j.biomaterials.2004.10.012 ↗
8. Jung WK, Koo HC, Kim KW et al (2008) Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol 74:2171–2178. doi: 10.1128/AEM.02001-0710.1128/AEM.02001-07 ↗
9. Le Ouay B, Stellacci F (2015) Antibacterial activity of silver nanoparticles: a surface science insight. Nano Today 10:339–354. doi: 10.1016/j.nantod.2015.04.00210.1016/j.nantod.2015.04.002 ↗
10. Lewinski N, Colvin V, Drezek R (2008) Cytotoxicity of nanoparticles. Small 4:26–49. doi: 10.1002/smll.20070059510.1002/smll.200700595 ↗
11. Li XZ, Nikaido H, Williams KE (1997) Silver-resistant mutants of Escherichia coli display active efflux of Ag+ and are deficient in porins. J Bacteriol 179:6127–613210.1128/jb.179.19.6127-6132.1997 ↗
12. Li F, Lei C, Shen Q et al (2013a) Analysis of copper nanoparticles toxicity based on a stress-responsive bacterial biosensor array. Nanoscale 5:653–662. doi: 10.1039/C2NR32156D10.1039/C2NR32156D ↗
13. Li L, Jiang W, Luo K et al (2013b) Superparamagnetic iron oxide nanoparticles as MRI contrast agents for non-invasive stem cell labeling and tracking. Theranostics 3:595–615. doi: 10.7150/thno.536610.7150/thno.5366 ↗
14. Maynard AD, Aitken RJ, Butz T et al (2006) Safe handling of nanotechnology. Nature 444:267–269. doi: 10.1038/444267a10.1038/444267a ↗
15. Mcquillan JS, Shaw AM (2014) Whole-cell Escherichia coli-based bio-sensor assay for dual zinc oxide nanoparticle toxicity mechanisms. Biosensors and Bioelectronic 51:274–279. doi: 10.1016/j.bios.2013.07.02410.1016/j.bios.2013.07.024 ↗
16. Morones-Ramirez JR, Winkler JA, Spina CS, Collins JJ (2013) Silver enhances antibiotic activity against gram-negative bacteria. Sci Transl Med 5:190ra81–190ra81. doi: 10.1126/scitranslmed.300627610.1126/scitranslmed.3006276 ↗
17. Nigra MM, Arslan I, Katz A (2012) Gold nanoparticle-catalyzed reduction in a model system: quantitative determination of reactive heterogeneity of a supported nanoparticle surface. J Catal 295:115–121. doi: 10.1016/j.jcat.2012.08.00110.1016/j.jcat.2012.08.001 ↗
18. Notter DA, Mitrano DM, Nowack B (2014) Are nanosized or dissolved metals more toxic in the environment? A meta-analysis. Environ Toxicol Chem 33:2733–2739. doi: 10.1002/etc.273210.1002/etc.2732 ↗
19. Nowack B, Brouwer C, Geertsma RE et al (2013) Analysis of the occupational, consumer and environmental exposure to engineered nanomaterials used in 10 technology sectors. Nanotoxicology 7:1152–1156. doi: 10.3109/17435390.2012.71186310.3109/17435390.2012.711863 ↗
20. Nowack B, Mueller NC, Krug HF, Wick P (2014) How to consider engineered nanomaterials in major accident regulations? Environ Sci Eur 26:2–10. doi: 10.1186/2190-4715-26-210.1186/2190-4715-26-2 ↗
21. Nowak A, Szade J, Talik E et al (2014) Structural, spectroscopic and biological investigation of copper oxides nanoparticles with various capping agents. Mater Chem Phys 145:465–470. doi: 10.1016/j.matchemphys.2014.02.04910.1016/j.matchemphys.2014.02.049 ↗
22. Nowak A, Szade J, Talik E et al (2016) Physicochemical and antibacterial characterization of ionocity Ag/Cu powder nanoparticles. Mater Charact 117:9–16. doi: 10.1016/j.matchar.2016.04.01310.1016/j.matchar.2016.04.013 ↗
23. Percival SL, Bowler PG, Russell D (2005) Bacterial resistance to silver in wound care. J Hosp Infect 60:1–7. doi: 10.1016/j.jhin.2004.11.01410.1016/j.jhin.2004.11.014 ↗
24. Prabhu S, Poulose EK (2012) Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 2:32–10. doi: 10.1186/2228-5326-2-3210.1186/2228-5326-2-32 ↗
25. Pradhan A, Seena S, Pascoal C, Cássio F (2011) Can metal nanoparticles be a threat to microbial decomposers of plant litter in streams? Microb Ecol 62:58–68. doi: 10.1007/s00248-011-9861-410.1007/s00248-011-9861-4 ↗
26. Raffi M, Mehrwan S, Bhatti TM et al (2010) Investigations into the antibacterial behavior of copper nanoparticles against Escherichia coli. Ann Microbiol 60:75–80. doi: 10.1007/s13213-010-0015-610.1007/s13213-010-0015-6 ↗
27. Ramazanzadeh B, Jahanbin A, Yaghoubi M et al (2015) Comparison of antibacterial effects of ZnO and CuO nanoparticles coated brackets against Streptococcus mutans. J Dent Shiraz Univ Med Sci 16:200–205
28. Santo CE, Lam EW, Elowsky CG et al (2011) Bacterial killing by dry metallic copper surfaces. Appl Environ Microbiol 77:794–802. doi: 10.1128/AEM.01599-1010.1128/AEM.01599-10 ↗
29. Schweiger C, Pietzonka C, Heverhagen J, Kissel T (2011) Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging. Int J Pharm 408:130–137. doi: 10.1016/j.ijpharm.2010.12.04610.1016/j.ijpharm.2010.12.046 ↗
30. Shobha G, Moses V, Amanda S (2014) Biological synthesis of copper nanoparticles and its impact—a review. International Journal of Pharmaceutical Science Invention 3:28–38
31. Silver S (2003) Bacterial silver resistance: molecular biology and uses and misuses of silver compounds. FEMS Microbiol Rev 27:341–353. doi: 10.1016/S0168-6445(03)00047-010.1016/S0168-6445(03)00047-0 ↗
32. Singh HP, Gupta N, Sharma SK, Sharma RK (2013) Synthesis of bimetallic Pt–Cu nanoparticles and their application in the reduction of rhodamine B. Colloids Surf A Physicochem Eng Asp 416:43–50. doi: 10.1016/j.colsurfa.2012.09.04810.1016/j.colsurfa.2012.09.048 ↗
33. Sowa-Söhle EN, Schwenke A, Wagener P et al (2013) Antimicrobial efficacy, cytotoxicity, and ion release of mixed metal (Ag, Cu, Zn, Mg) nanoparticle polymer composite implant material. BioNanoMaterials 14:1–11. doi: 10.1515/bnm-2013-001210.1515/bnm-2013-0012 ↗
34. Suh WH, Suslick KS, Stucky GD, Suh Y-H (2009) Nanotechnology, nanotoxicology, and neuroscience. Prog Neurobiol 87:133–170. doi: 10.1016/j.pneurobio.2008.09.00910.1016/j.pneurobio.2008.09.009 ↗
35. Sun TY, Gottschalk F, Hungerbühler K, Nowack B (2014) Comprehensive probabilistic modelling of environmental emissions of engineered nanomaterials. Environ Pollut 185:69–76. doi: 10.1016/j.envpol.2013.10.00410.1016/j.envpol.2013.10.004 ↗
36. Valodkar M, Modi S, Pal A, Thakore S (2010) Synthesis and anti-bacterial activity of Cu, Ag and Cu–Ag alloy nanoparticles: a green approach. Mater Res Bull 46:384–389. doi: 10.1016/j.materresbull.2010.12.00110.1016/j.materresbull.2010.12.001 ↗
37. Vance ME, Kuiken T, Vejerano EP et al (2015) Nanotechnology in the real world: redeveloping the nanomaterial consumer products inventory. Beilstein J Nanotechnol 6:1769–1780. doi: 10.3762/bjnano.6.18110.3762/bjnano.6.181 ↗
38. Vaseem M, Umar A, Hahn YB (2010) ZnO nanoparticles: growth, properties, and applications. In: Umar A, Hahn YB (eds) Metal oxide nanostructures and their applications, vol 5. American scientific publishers, New York, pp 1–36
39. Yah CS, Simat ES, Iyuke SE (2012) Nanoparticles toxicity and their routes of exposures. Pak J Pharm Sci 25:477–491