Model for electron emission of high-Z radio-sensitizing nanoparticle irradiated by X-rays
Source abstract
Abstract
In this paper we develop a new model for the electron emission of high-Z nanoparticle irradiated by X-rays. This study is motivated by the recent advances about the nanoparticle enhancement of cancer treatment by radiotherapy. Our original approach combines a pure probabilistic analytical model for the photon trajectories inside the nanoparticle and subsequent electron cascade trajectories based here on a Monte-Carlo simulation provided by the Livermore model implemented in Geant4. To compare the nanoparticle and the plane surface electron emissions, we also develop our model for a plane surface. Our model highlights and explains the existence of a nanoparticle optimal radius corresponding to a maximum of nanoparticle electron emission. It allows us to study precisely the nanoparticle photon absorption and electron cascade production depth in the nanoparticle.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Radiation Therapy and Dosimetry · Advanced Radiotherapy Techniques · Electron and X-Ray Spectroscopy Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (21)
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