Modeling drug release from functionalized magnetic nanoparticles actuated by non-heating low frequency magnetic field
Source abstract
Abstract
Various plausible acceleration mechanisms of drug release from nanocarriers composed of a single-domain magnetic nanoparticle core with attached long macromolecule chains activated by low frequency non-heating alternating magnetic field (AMF) are discussed. The most important system characteristics affecting the AMF exposure impact are determined. Impact of several reasonable mechanisms is estimated analytically or obtained using numerical modeling. Some conditions providing manifold release acceleration as a result from exposure in AMF are found.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Microfluidic and Bio-sensing Technologies · Electrohydrodynamics and Fluid Dynamics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (64)
Show source-provided references
1. Abakumov MA, Nukolova NV, Sokolsky-Papkov M, Shein SA, Sandalova TO, Vishwasrao HM, Grinenko NF, Gubsky IL, Abakumov AM, Kabanov AV, Chekhonin VP (2015) VEGF-targeted magnetic nanoparticles for MRI visualization of brain tumor. Nanomedicine: Nanotechnology, Biology, and Medicine 11:825–833. doi: 10.1016/j.nano.2014.12.01110.1016/j.nano.2014.12.011 ↗
2. Banchelli M, Nappini S, Montis C, Bonini M, Canton P, Berti D, Baglioni P (2014) Magnetic nanoparticle clusters as actuators of ssDNA release. Phys Chem Chem Phys 16:10023–10031. doi: 10.1039/C3CP55470H10.1039/C3CP55470H ↗
3. Cengelli F, Maysinger D, Tschudi-Monnet F, Montet X, Corot C, Petri-Fink A, Hofmann H, Juillerat-Jeanneret L (2006) Interaction of functionalized superparamagnetic iron oxide nanoparticles with brain structures. J Pharmacol Exp Ther 318(1):108–116. doi: 10.1124/jpet.106.10191510.1124/jpet.106.101915 ↗
4. Contreras MF, Sougrat R, Zaher A, Ravasi T, Kosel J (2015) Non-chemotoxic induction of cancer cell death using magnetic nanowires. Int J Nanomedicine 10:2141. doi: 10.2147/IJN.S7708110.2147/IJN.S77081 ↗
5. Dobson J (2008) Remote control of cellular behaviour with magnetic nanoparticles. Nat Nanotechnol 3:139–143. doi: 10.1038/nnano.2008.3910.1038/nnano.2008.39 ↗
6. Dobson J (2010) Cancer therapy: a twist on tumour targeting. Nat Mater 9:95–96. doi: 10.1038/nmat260410.1038/nmat2604 ↗
7. Dobson J, Cartmell SH, Keramane A, El Haj AJ (2006) Principles and design of a novel magnetic force mechanical conditioning bioreactor for tissue engineering, stem cell conditioning, and dynamic in vitro screening. IEEE Trans Nanobioscience 5:173–17710.1109/TNB.2006.880823 ↗
8. Dutz S, Hergt R (2014) Magnetic particle hyperthermia—a promising tumour therapy? Nanotechnology 25:452001–452029. doi: 10.1088/0957-4484/25/45/45200110.1088/0957-4484/25/45/452001 ↗
9. Gleich B (2014) Principles and applications of magnetic particle imaging. Springer Vieweg10.1007/978-3-658-01961-7 ↗
10. Golovin YI, Gribanovskii SL, Golovin DY, Klyachko N, Kabanov A (2014) Single-domain magnetic nanoparticles in an alternating magnetic field as mediators of local deformation of the surrounding macromolecules. Phys Solid State 56:1342–1351. doi: 10.1134/S106378341407014210.1134/S1063783414070142 ↗
11. Golovin YI, Gribanovsky SL, Golovin DY, Klyachko NL, Majouga AG, Master АM, Sokolsky M, Kabanov AV (2015) Towards nanomedicines of the future: remote magneto-mechanical actuation of nanomedicines by alternating magnetic fields. J Control Release 219:43–60. doi: 10.1016/j.jconrel.2015.09.03810.1016/j.jconrel.2015.09.038 ↗
12. Golovin YI, Klyachko NL, Golovin DY, Efremova MV, Samodurov AA, Sokolski-Papkov M, Kabanov AV (2013) A new approach to the control of biochemical reactions in a magnetic nanosuspension using a low-frequency magnetic field. Tech Phys Lett 39:240–243. doi: 10.1134/S106378501303005X10.1134/S106378501303005X ↗
13. Golovin YI, Klyachko NL, Gribanovskii SL, Golovin DY, Majouga AG (2016) Model of controlled drug release from functionalized magnetic nanoparticles by a nonheating alternating-current magnetic field. Tech Phys Lett 42(3):267–270. doi: 10.1134/S106378501603005610.1134/S1063785016030056 ↗
14. Guo H, Chen W, Sun X, Liu YN, Li J, Wang J (2015) Theranostic magnetoliposomes coated by carboxymethyl dextran with controlled release by low-frequency alternating magnetic field. Carbohydr Polym 118:209–217. doi: 10.1016/j.carbpol.2014.10.07610.1016/j.carbpol.2014.10.076 ↗
15. Handbook of biological effects of electromagnetic fields. Bioengineering and biophysical aspects of electromagnetic fields. Third edition (2007) Barnes FS and Greenebaum B (eds). Boca Raton. CRC Press
16. Haney MJ, Suresh P, Zhao Y, Kanmogne GD, Kadiu I, Sokolsky-Papkov M, Klyachko NL, Mosley RL, Kabanov AV, Gendelman HE, Batrakova EV (2012) Blood-borne macrophage-neural cell interactions hitchhike endosome networks for cell-based nanozyme brain delivery. Nanomedicine (Lond) 7(6):815–833. doi: 10.2217/nnm.11.15610.2217/nnm.11.156 ↗
17. Hanus J, Ullrich M, Dohnal J, Singh M, Stepanek F (2013) Remotely controlled diffusion from magnetic liposome microgels. Langmuir 29:4381–4387. doi: 10.1021/la400031810.1021/la4000318 ↗
18. Hoare T, Santamaria J, Goya GF, Irusta S, Lin D, Lau S, Padera R, Langer R, Kohane DS (2009) A magnetically triggered composite membrane for on-demand drug delivery. Nano Lett 9:3651–3657. doi: 10.1021/nl901893510.1021/nl9018935 ↗
19. Hoare T, Timko BP, Santamaria J, Goya GF, Irusta S, Lau S, Stefanescu CF, Lin D, Langer R, Kohane DS (2011) Magnetically triggered nanocomposite membranes: a versatile platform for triggered drug release. Nano Lett 11:1395–1400. doi: 10.1021/nl200494t10.1021/nl200494t ↗
20. Howard KA, Vorup-Jensen T, Peer D (eds.) Nanomedicine. Advances in delivery science and technology (2016). Springer, New York. doi: 10.1007/978-1-4939-3634-2 .10.1007/978-1-4939-3634-2 ↗
21. Hu B, Dobson J, El Haj AJ (2014) Control of smooth muscle alpha-actin (SMA) up-regulation in HBMSCs using remote magnetic particle mechano-activation. Nanomedicine 10:45–55. doi: 10.1016/j.nano.2013.06.01410.1016/j.nano.2013.06.014 ↗
22. Hu B, El Haj AJ, Dobson J (2013) Receptor-targeted, magneto-mechanical stimulation of osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. Int J Mol Sci 14:19276–19293. doi: 10.3390/ijms14091927610.3390/ijms140919276 ↗
23. Hughes S, Dobson J, El Haj AJ (2007) Magnetic targeting of mechanosensors in bone cells for tissue engineering applications. J Biomech 40:S96–104. doi: 10.1016/j.jbiomech.2007.03.00210.1016/j.jbiomech.2007.03.002 ↗
24. Hughes S, El Haj AJ, Dobson J (2005) Magnetic micro- and nanoparticle mediated activation of mechanosensitive ion channels. Med Eng Phys 27:754–762. doi: 10.1016/j.medengphy.2005.04.00610.1016/j.medengphy.2005.04.006 ↗
25. Hughes S, McBain S, Dobson J, El Haj AJ (2008) Selective activation of mechanosensitive ion channels using magnetic particles. J R Soc Interface 5:855–863. doi: 10.1098/rsif.2007.127410.1098/rsif.2007.1274 ↗
26. Jaiswal MK, De M, Chou SS, Vasavada S, Bleher R, Prasad PV, Bahadur D, Dravid VP VP (2014) Thermoresponsive magnetic hydrogels as theranostic nanoconstructs. ACS Appl Mater Interfaces 6:6237–6247. doi: 10.1021/am501067j10.1021/am501067j ↗
27. Jeyadevan B (2010) Present status and prospects of magnetite nanoparticles-based hyperthermia. Ceramic Soc Japan 118:391–401. doi: 10.2109/jcersj2.118.39110.2109/jcersj2.118.391 ↗
28. Kanczler JM, Sura HS, Magnay J, Green D, Oreffo RO, Dobson JP, El Haj AJ (2010) Controlled differentiation of human bone marrow stromal cells using magnetic nanoparticle technology. Tissue Eng Part A 16:3241–3250. doi: 10.1089/ten.TEA.2009.063810.1089/ten.TEA.2009.0638 ↗
29. Kazakov S (2016) Liposome-nanogel structures for future pharmaceutical applications: an updated review. Current Pharm Design 22(10):1391–1413. doi: 10.2174/1381612822666160125114733#sthash.RJ81J3LK.dpuf10.2174/1381612822666160125114733#sthash.RJ81J3LK.dpuf ↗
30. Keblinski P, Cahill DG, Bodapati A, Sullivan CR, Taton TA (2006) Limits of localized heating by electromagnetically excited nanoparticles. J Appl Phys 100:054305. doi: 10.1063/1.233578310.1063/1.2335783 ↗
31. Kim DH, Karavayev P, Rozhkova EA, Pearson J, Yefremenko V, Bader SD, Novosad V (2011) Mechanoresponsive system based on sub-micron chitosan-functionalized ferromagnetic disks. J Mater Chem 21:8422–8426. doi: 10.1039/C1JM10272A10.1039/C1JM10272A ↗
32. Kim DH, Rozhkova EA, Ulasov IV, Bader SD, Rajh T, Lesniak MS, Novosad V (2010) Biofunctionalized magnetic-vortex microdiscs for targeted cancer-cell destruction. Nat Mater 9:165–171. doi: 10.1038/nmat259110.1038/nmat2591 ↗
33. Klyachko NL, Sokolsky-Papkov M, Pothayee N, Efremova MV, Gulin DA, Pothayee N, Kuznetsov AA, Majouga AG, Riffle JS, Golovin YI, Kabanov AV (2012) Changing the enzyme reaction rate in magnetic nanosuspensions by a non-heating magnetic field. Angewandte ChemieInt Edition 51(48):12016–12019. doi: 10.1002/anie.20120590510.1002/anie.201205905 ↗
34. Knopp T, Buzug TM (2012) Magnetic particle imaging. Springer-Verlag, An introduction to imaging principles and scanner instrumentation10.1007/978-3-642-04199-0 ↗
35. Kobayashi H, Ueda K, Tomitaka A, Yamada T, Takemura Y (2011) Self-heating property of magnetite nanoparticles dispersed in solution. IEEE Trans Magn 47:4151–4154. doi: 10.1109/TMAG.2011.215747210.1109/TMAG.2011.2157472 ↗
36. Kozissnik B, Bohorquez AC, Dobson J, Rinaldi C (2013) Magnetic fluid hyperthermia: advances, challenges, and opportunity. Int J Hyperth 29:706–714. doi: 10.3109/02656736.2013.83720010.3109/02656736.2013.837200 ↗
37. Kunjachan S, Ehling J, Storm G, Kiessling F, Lammers T (2015) Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects. Chem Rev 115(19):10907–10937. doi: 10.1021/cr500314d10.1021/cr500314d ↗
38. Landau LD, Lifshitz EM (1987) Theoretical physics. V.6. Fluid mechanics. (2nd ed.). Butterworth-Heinemann. ISBN 978–0–08-033933-7
39. Lee N, Yoo D, Ling D, Cho MH, Hyeon T, Cheon J (2015) Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy. Chem Rev 115:10637–10689. doi: 10.1021/acs.chemrev.5b0011210.1021/acs.chemrev.5b00112 ↗
40. Leulmi S, Chauchet X, Morcrette M, Ortiz G, Joisten H, Sabon P, Livache T, Hou Y, Carrière M, Lequiena S, Dieny B (2015) Triggering the apoptosis of targeted human renal cancer cells by the vibration of anisotropic magnetic particles attached to the cell membrane. Nanoscale 7:15904–15914. doi: 10.1039/c5nr03518j10.1039/c5nr03518j ↗
41. Lim EK, Kim T, Paik S, Haam S, Huh YM, Lee K (2015) Nanomaterials for theranostics: recent advances and future challenges. Chem Rev 115(1):327–394. doi: 10.1021/cr300213b10.1021/cr300213b ↗
42. Ling-Yun Z, Jia-Yi L, Wei-Wei O, Dan-Ye L, Li L, Li-Ya L, Jin-Tian T (2013) Magnetic-mediated hyperthermia for cancer treatment: research progress and clinical trials. Chin Phys B 22:108104–1/108104-14. doi: 10.1088/1674-1056/22/10/10810410.1088/1674-1056/22/10/108104 ↗
43. Mannix RJ, Kumar S, Cassiola F, Montoya-Zavala M, Feinstein E, Prentiss M, Ingber DE (2008) Nanomagnetic actuation of receptor-mediated signal transduction. Nat Nanotechnol 3:36–40. doi: 10.1038/nnano.2007.41810.1038/nnano.2007.418 ↗
44. Mizuki T, Watanabe N, Nagaoka Y, Fukushima T, Morimoto H, Usami R, Maekawa T (2010) Activity of an enzyme immobilized on superparamagnetic particles in a rotational magnetic field. Biochem Biophys Res Commun 393:779–782. doi: 10.1016/j.bbrc.2010.02.08110.1016/j.bbrc.2010.02.081 ↗
45. Nappini S, Bombelli FB, Bonini M, Norden B, Baglioni P (2010) Magnetoliposomes for controlled drug release in the presence of low-frequency magnetic field. Soft Matter 6:154–162. doi: 10.1039/B915651H10.1039/B915651H ↗
46. Nappini S, Bonini M, Ridi F, Baglioni P (2011) Structure and permeability of magnetoliposomes loaded with hydrophobic magnetic nanoparticles in the presence of a low frequency magnetic field. Soft Matter 7:4801–4811. doi: 10.1039/C0SM01264E10.1039/C0SM01264E ↗
47. Obaidat M, Issa B, Haik Y (2015) Magnetic properties of magnetic nanoparticles for efficient hyperthermia. Nanomaterials 5:63–89. doi: 10.3390/nano501006310.3390/nano5010063 ↗
48. Panagiotopoulos N, Duschka RL, Ahlborg M, Bringout G, Debbeler C, Graeser M, Kaethner C, Lüdtke-Buzug K, Medimagh H, Stelzner J, Buzug TM, Barkhausen J, Vogt FM, Haegele J (2015) Magnetic particle imaging: current developments and future directions. Int J Nanomedicine 10:3097–3114. doi: 10.2147/IJN.S7048810.2147/IJN.S70488 ↗
49. Pankhurst QA, Thanh NTK, Jones SK, Dobson J (2009) Progress in applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys 42:224001. doi: 10.1088/0022-3727/42/22/22400110.1088/0022-3727/42/22/224001 ↗
50. Pattni BS, Chupin VV, Torchilin VP (2015) New developments in liposomal drug delivery. Chem Rev 115(19):10938–10966. doi: 10.1021/acs.chemrev.5b0004610.1021/acs.chemrev.5b00046 ↗
51. Perigo EA, Hemery G, Sandre O, Ortega D, Garaio E, Plazaola F, Teran FJ (2015) Fundamentals and advances in magnetic hyperthermia. Applied Physics Reviews 2:041302. doi: 10.1063/1.493568810.1063/1.4935688 ↗
52. Rabin Y (2002) Is intracellular hyperthermia superior to extracellular hyperthermia in the thermal sense? Int J Hyperth 18:194–202. doi: 10.1080/0265673011011671310.1080/02656730110116713 ↗
53. Rozhkova EA, Ulasov IV, Kim DH, Dimitrijevic NM, Novosad V, Bader SD, Lesniak MS, Rajh T (2011) Multifunctional nano-bio materials within cellular machinery. Int J Nanosci 10:899. doi: 10.1142/S0219581X1100935010.1142/S0219581X11009350 ↗
54. Salunkhe AB, Khot VM, Pawar SH (2014) Magnetic hyperthermia with magnetic nanoparticles: a status review. Curr Top Med Chem 14:572–594. doi: 10.2174/156802661466614011820355010.2174/1568026614666140118203550 ↗
55. Santos LJ, Reis RL, Gomes ME (2015) Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering. Review Trends in Biotechnology 33(8):471–479. doi: 10.1016/j.tibtech.2015.06.00610.1016/j.tibtech.2015.06.006 ↗
56. Semkina AS, Abakumov MA, Abakumov AM, Nukolova NV, Chekhonin VP (2016) Relationship between the size of magnetic nanoparticles and efficiency of MRT imaging of cerebral glioma in rats. Bull Exp Biol Med 161(2):292–295. doi: 10.1007/s10517-016-3398-y10.1007/s10517-016-3398-y ↗
57. Vitol EA, Novosad V, Rozhkova EA (2012a) Microfabricated magnetic structures for future medicine: from sensors to cell actuators. Nanomedicine (Lond) 7:1611–1624. doi: 10.2217/nnm.12.13310.2217/nnm.12.133 ↗
58. Vitol EA, Novosad V, Rozhkova EA (2012b) Multifunctional ferromagnetic disks for modulating cell function. IEEE T Magn 48:3269–3274. doi: 10.1109/TMAG.2012.219820910.1109/TMAG.2012.2198209 ↗
59. Vulic K, Pakulska MM, Sonthalia R, Ramachandran A, Shoichet MS (2015) Mathematical model accurately predicts protein release from an affinity-based delivery system. J. of controlled release 197:69–77. doi: 10.1016/j.jconrel.2014.10.03210.1016/j.jconrel.2014.10.032 ↗
60. Wang B, Bienvenu C, Mendez-Garza J, Madeira PA, Vierling P, Di Giorgio C, Bossis G (2013) Necrosis of HepG2 cancer cells induced by the vibration of magnetic particles. J of Magnetism and Magnetic Materials 344:193–201. doi: 10.1016/j.jmmm.2013.05.04310.1016/j.jmmm.2013.05.043 ↗
61. Weiser JR, Saltzman WM (2014) Controlled release for local delivery of drugs: barriers and models. J of controlled release 190:664–673. doi: 10.1016/j.jconrel.2014.04.04810.1016/j.jconrel.2014.04.048 ↗
62. Wilhelm S, Tavares AJ, Dai Q, Ohta S, Audet J, Dvorak HF, Chan WCW (2016) Analysis of nanoparticle delivery to tumours. Nature Reviews Materials 1(16014):1–12. doi: 10.1038/natrevmats.2016.1410.1038/natrevmats.2016.14 ↗
63. Yun YH, Lee BK, Park K (2015) Controlled drug delivery: historical perspective for the next generation. J of control release 219:2–7. doi: 10.1016/j.jconrel.2015.10.00510.1016/j.jconrel.2015.10.005 ↗
64. Zhang E, Kircher MF, Koch XM, Eliasson L, Goldberg SN, Renström E (2014) Dynamic magnetic fields remote-control apoptosis via nanoparticle rotation. ACS Nano 8(4):3192–3201. doi: 10.1021/nn406302j10.1021/nn406302j ↗