Nanosafety practices: results from a national survey at research facilities
Source abstract
Abstract
The exposure to engineered nanomaterials (ENMs) is a new emerging risk at work due to an increase in the number of workers potentially exposed to them and the current lack of data on their health and safety risks. This paper reports the findings of a survey designed to study the safety practices employed by workers in Spanish research facilities performing tasks involving the use of ENMs at research level. A questionnaire pretested and validated by an expert panel was sent by e-mail to the target audience. The 425 surveys completed show that most of the respondents handled up to 5 different ENMs, in suspension, in small amounts during short periods of exposure. The implementation of common hygienic practices, such as the use of protection for hands and the implementation of fume hoods, is widely indicated. The selection of the preventive and protective measures does not depend on the characteristics of ENMs handled. Also, the risks posed by ENMs are widely ignored. Besides the performance of risk assessment, hygienic monitoring and the conducting of a specific health surveillance are practically non-existent although some accidents relating to ENMs were identified. In conclusion, workers’ exposure to ENMs seems to be low. Even though the best practices and preventive and protective measures reported were employed, most of the respondents could not be correctly protected. Moreover, workers do not associate the measures implemented with the nanorisks. Finally, there is a lack of proactive action underway to protect the workers, and concerns about safety are weakly evidenced.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Air Quality and Health Impacts · Chemical Safety and Risk Management
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (65)
Show source-provided references
1. Adlakha-Hutcheon, G., Khaydarov, R., Korenstein, R., Varma, R., Vaseashta, A., Stamm, H., Abdel-Mottaleb, M. (2009). NANOMATERIALS, NANOTECHNOLOGY applications, consumer products, and benefits. Nanomaterials: Risks and Benefits, 195–207. doi: 10.1007/978-1-4020-9491-0_1410.1007/978-1-4020-9491-0_14 ↗
2. ANEC/BEUC (2015) ANEC/BEUC inventory of products claiming to contain nanoparticles available on the EU market. Accessed 26/7, 2013, from http://docshare.beuc.org/Common/GetFile.asp?ID=30511&mfd=off&LogonName=Guesten
3. Balas F, Arruebo M, Urrutia J, Santamaria J (2010) Reported nanosafety practices in research laboratories worldwide. Nat Nanotechnol 5(2):93–96. doi: 10.1038/nnano.2010.110.1038/nnano.2010.1 ↗
4. Bai Y, Zhang Y, Zhang J, Mu Q, Zhang W, Butch ER, Snyder SE, Yan B (2010) Repeated administrations of carbon nanotubes in male mice cause reversible testis damage without affecting fertility. Nat Nanotechnol 5:683–68910.1038/nnano.2010.153 ↗
5. Berkeley City Council (2006) The Manufactured Nanoscale Health and Safety Ordinance: Section 15.12.040
6. Bergamaschi E (2009) Occupational exposure to nanomaterials: present knowledge and future development. Nanotoxicology 3(3):194–201. doi: 10.1080/1743539090303703810.1080/17435390903037038 ↗
7. Boutou-Kempf O (2010) Feasibility of an epidemiological surveillance system for workers occupationally exposed to engineered nanomaterials
8. Brun E, Op de Beeck R, Van Herpe S, Isotalo L, Laamanen I, Blotière C, Guimon M, Solans X et al (2008) European risk observatory report - expert forecast on emerging chemical risks related to occupational safety and health. Office for Official Publications of the European Communities, Luxemburg
9. Conti JA, Killpack K, Gerritzen G, Huang L, Mircheva M, Delmas M, Harthorn BH, Holden PA et al (2008) Health and safety practices in the nanomaterials workplace: results from an international survey. Environmental Science & Technology 42(9):3155–3162. doi: 10.1021/es702158q10.1021/es702158q ↗
10. Cornelissen RTM, Samwel-Luijt M, Vervoort MBHJ, Hoeneveld D (2014). Use of engineered nanomaterials in Dutch academic research settings. Sofokles
11. Díaz Soler BM, López Alonso M, Martínez Aires MD (2015) A survey of health and safety practices in the Spanish research laboratories studying nanomaterials. In WOS2015 Scientific Committee (Ed.), WOS 8th international conference - proceedings. Porto, Portugal
12. Dimitrijevic D (2010) Dangers of nanotechnology: potential fire concerns and safety frameworks. Int J Emerg Manag 7(3–4):249–257. doi: 10.1504/IJEM.2010.03700910.1504/IJEM.2010.037009 ↗
13. Engeman, C. D., Baumgartner, L., Carr, B. M., Fish, A. M., Meyerhofer, J. D., Satterfield, T. A., Holden, PA et al. Harthorn, B. H. (2012). Governance implications of nanomaterials companies’ inconsistent risk perceptions and safety practices. J Nanopart Res, 14(3) doi: 10.1007/s11051-012-0749-010.1007/s11051-012-0749-0 ↗
14. European Agency for Safety and Health at Work (EU-OSHA). (2009) Previsiones de los expertos sobre los riesgos químicos emergentes en relación con la seguridad y la salud en el trabajo. Facts, 84
15. European Commission (2005) European survey on success factors barriers and deeds for the industrial uptake of nanomaterials in SMEs
16. European Commission (2012) Types and uses of nanomaterials accompanying the Communication from the Commission to the European Parliament, the Council and the European Economic and Social Committee on the Second Regulatory Review on Nanomaterials. Commission Staff Working Paper
17. European Commission (2013) High-level expert group on key enabling technologies. Accessed 8/22, 2013, from http://ec.europa.eu/enterprise/sectors/ict/key_technologies/kets_high_level_group_en.htm
18. European NanoBusiness Association (2005) The European NanoBusiness survey. The European NanoBusiness Association
19. Gao N, Zhang Q, Mu Q, Bai Y, Li L, Zhou H, Butch ER, Powell TB, Snyder SE, Jiang G, Yan B (2011) Steering carbon nanotubes to scavenger receptor recognition by nanotube surface chemistry modification partially alleviates NFκB activation and reduces its immunotoxicity. ACS Nano 5:4581–459110.1021/nn200283g ↗
20. Gerritzen G, Huang L, Killpack K, Murcheva M, Conu J (2006) A review of current practices in the nanotechnology industry International Council on Nanotechnology (ICON).
21. Gibbs LM, Lamba F, Stoxkmeier BC, Kojola W (2012) General safe practices for working with engineered nanomaterials in research laboratories National Institute for Occupational Safety and Health (NIOSH)
22. Helland A, Kastenholz H, Siegrist M (2008) Precaution in practice: perceptions, procedures, and performance in the nanotech industry. J Ind Ecol 12(3):449–458. doi: 10.1111/j.1530-9290.2008.00053.x10.1111/j.1530-9290.2008.00053.x ↗
23. Hwang D, Bradley J (2010) The recession’s ripple effect on nanotech Lux Research. Inc
24. IBM (2013) Nueva versión de IBM SPSS statistics 21. Accessed 5/25, 2013, from http://www-01.ibm.com/software/es/stats21/index.html
25. Institute of Occupational Medicine (2004) Nanoparticles: An occupational hygiene review
26. Instituto Nacional de Seguridad e Higiene en el Trabajo (INSHT) (2015a) Riesgos derivados de la exposición a nanomateriales en distintos sectores: Construcción. Documentos Técnicos
27. Instituto Nacional de Seguridad e Higiene en el Trabajo (INSHT) (2015b) Seguridad y salud en el trabajo con nanomateriales. Documento Técnico
28. Instituto Nacional de Seguridad e Higiene en el Trabajo (INSHT) (2016) Riesgos derivados de la exposición a nanomateriales en distintos sectores: Automoción. Documentos Técnicos
29. ISO (2011) TS 8004–1:2010 nanotechnologies - vocabulary - part 1: Core terms
30. Jacquet F (2012) Repérage des salariés potentiellement exposés aux nanoparticules
31. Kermanizadeh A, Balharry D, Wallin H, Loft S, Moller P (2015) Nanomaterial translocation-the biokinetics, tissue accumulation, toxicity and fate of materials in secondary organs-a review. Crit Rev Toxicol 45(10):837–872. doi: 10.3109/10408444.2015.105874710.3109/10408444.2015.1058747 ↗
32. Landeta RJ (1999) In Talleres HUROPE S. L. (Ed.), El método Delphi (Primera ed.). Barcelona: Editorial Ariel, S.A
33. Lekas D, Lifset R, Rejeski D (2006) Nanotechnology startup concerns, information needs, and opportunities to proactively address environmental, health, and social issues. Focus on firms in Connecticut and New York
34. LimeSurvey (2016) LimeSurvey, from https://www.limesurvey.org/
35. Lindberg J, & Quinn M (2007) A survey of environmental, health and safety risk management information needs and practices among nanotechnology firms in the Massachusetts region
36. Lindberg HK, Falck GC, Suhonen S, Vippola M, Vanhala E, Catalán J, Savolainen K, Norppa H et al (2009) Genotoxicity of nanomaterials: DNA damage and micronuclei induced by carbon nanotubes and graphite nanofibres in human bronchial epithelial cells in vitro. Toxicol Lett 186(3):166–173. doi: 10.1016/j.toxlet.2008.11.01910.1016/j.toxlet.2008.11.019 ↗
37. Liou, S.H, Tsai, C. S. J., Pelclova, D., Schubauer-Berigan, M. K., Schulte, P. A. (2015). Assessing the first wave of epidemiological studies of nanomaterial workers. J Nanopart Res, 17(10) doi: 10.1007/s11051-015-3219-710.1007/s11051-015-3219-7 ↗
38. Ministerio de la Presidencia (1997) Real Decreto 665/1997, de 12 de mayo, sobre la protección de los trabajadores contra los riesgos relacionados con la exposición a agentes cancerígenos durante el trabajo: BOE-A-1997-11145
39. Ministerio de la Presidencia (2001) Real Decreto 374/2001 de 6 de abril sobre la protección de la salud y seguridad de los trabajadores contra los riesgos relacionados con los agentes químicos durante el trabajo: BOE n° 104 01–05-2001
40. Ministerio de la Presidencia (2003) Real Decreto 681/2003, de 12 de junio, sobre la protección de la salud y la seguridad de los trabajadores expuestos a los riesgos derivados de atmósferas explosivas en el lugar de trabajo
41. Ministerio de Trabajo y Seguridad Social (1995) Ley 31/1995, de 8 de noviembre, de Prevención de Riesgos Laborales. BOE-A-1995-24292
42. Mu Q, Su G, Li L, Gilbertson BO, Yu LH, Zhang Q, Sun Y, Yan B (2012) Size-dependent cell uptake of protein-coated graphene oxide nanosheets. ACS Appl Mater Interfaces 4:2259–226610.1021/am300253c ↗
43. Mu Q, Jiang G, Chen L, Zhou H, Fourches D, Tropsha A, Yan B (2014) Chemical basis of interactions between engineered nanoparticles and biological systems. Chem Rev 114:7740–778110.1021/cr400295a ↗
44. NANoREG (2017) NANoREG –A common European approach to the regulatory testing of Manufactured Nanomaterials. In: http://www.nanoreg.eu/project/nanoreg-objectives
45. NEPHH’S CONSORTIUM (2012) Guidelines for responsible management of waste nanomaterials EU FP7
46. Oberdörster G, Oberdörster E, Oberdörster J (2005b) Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect:173–179. doi: 10.1289/ehp.733910.1289/ehp.7339 ↗
47. Oberdörster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, Carter J, Yang H et al (2005a) Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group 2:8
48. Occupational Safety and Health Administration (OSHA) (2008) CFR 1910.132. General requirements: Personal protective equipment. Washington D.C
49. Occupational Safety and Health Administration (OSHA) (2010) Introduction to nanomaterials and occupational safety and health.SH-21008-10-60-F-48
50. Phantoms Fundations (2012) Nanoscience and nanotechnology in Spain
51. Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WAH, Seaton A, Stone V, Donaldson K et al (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3(7):423–428. doi: 10.1038/nnano.2008.11110.1038/nnano.2008.111 ↗
52. Pritchard DK (2004) Literature review. Explosion hazards associated with nanopowders. Accessed 6/22, 2013, from http://www.hse.gov.uk/research/hsl_pdf/2004/hsl04-12.pdf
53. Ricaud M, Witschger O (2012) Les nanomatériaux: Definitions, risques toxicologiques, caractérisation de l'exposition professionnelle et mesures de prevention Institut National de Recherche et de Sécurité
54. Rosell MG, Pujol L (2008) Nota técnica de prevención 797: Riesgos asociados a la nanotecnología Instituto Nacional de Seguridad e Higiene en el Trabajo
55. Savolainen K, Alenius H, Norppa H, Pylkkanen L, Tuomi T, Kasper G (2010) Risk assessment of engineered nanomaterials and nanotechnologies-a review. Toxicology 269(2–3):92–104. doi: 10.1016/j.tox.2010.01.01310.1016/j.tox.2010.01.013 ↗
56. Schmid K, Danuser B, Riediker M (2010) Nanoparticle usage and protection measures in the manufacturing industry--a representative survey. J Occup Environ Hyg 7(4):224–232. doi: 10.1080/1545962100360912710.1080/15459621003609127 ↗
57. Schmid K, Riediker M (2008) Use of nanoparticles in Swiss industry: a targeted survey. Environmental Science & Technology 42(7):2253–2260. doi: 10.1021/es071818o10.1021/es071818o ↗
58. Shukla RK, Kumar A, Gurbani D, Pandey AK, Singh S, Dhawan A (2013) TiO2 nanoparticles induce oxidative DNA damage and apoptosis in human liver cells. Nanotoxicology 7(1):48–60. doi: 10.3109/17435390.2011.62974710.3109/17435390.2011.629747 ↗
59. Soni D, Naoghare PK, Saravanadevi S, Pandey RA (2015) Release, transport and toxicity of engineered nanoparticles. Reviews of Environmental Contamination and Toxicology, Vol 234(234):1–47. doi: 10.1007/978-3-319-10638-0_110.1007/978-3-319-10638-0_1 ↗
60. Takagi A, Hirose A, Nishimura T, Fukumori N, Ogata A, Ohashi N, Kitajima S, Kanno J et al (2008) Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(1):105–116. doi: 10.2131/jts.33.10510.2131/jts.33.105 ↗
61. Tanarro C (2010) Nota técnica de prevención 877: Evaluación del riesgo por exposición a nanopartículas mediante el uso de metodologías simplificadas Instituto Nacional de Seguridad e Higiene en el Trabajo
62. Tanarro C, Gálvez V (2009). Nanopartículas: ¿un riesgo pequeño? Instituto de Seguridad e Higiene en el Trabajo
63. Van Broekhuizen F, Van Broekhuizen P (2009). Nano-products in the European construction industry. European Federation of Building and Wood Workers and European Construction Industry Federation
64. Zhang C, Zhang J, Wang G (2014) Current safety practices in nano-research laboratories in china. J Nanosci Nanotechnol 14(6):4700–4705. doi: 10.1166/jnn.2014.864910.1166/jnn.2014.8649 ↗
65. Zhang Y, Tekobo S, Tu Y, Zhou Q, Jin X, Dergunov SA, Pinkhassik E, Yan B (2012) Permission to enter cell by shape: Nanodisk vs Nanosphere. ACS Appl Mater Interfaces 4:4099–410510.1021/am300840p ↗