Are stirring and sonication pre-dispersion methods equivalent for in vitro toxicology evaluation of SiC and TiC?
Source abstract
Abstract
The evolution of the particle size distribution and the surface composition of silicon carbide and titanium carbide nanoparticle (NP) dispersions were studied. The pre-dispersions were prepared using two commonly used protocols for dispersion: stirring and sonication. Two dispersants were investigated (water and Pluronic F108 1 %) at two stages: predispersion and during in vitro assays. Our data show that for each tested condition, different time-dependent results for the surface chemical composition as well as size and percentage of the agglomerates and the primary particles are observed. De-agglomeration and successive or simultaneous cleaning-wrapping cycles of the nanomaterial are observed and are related to the dispersion method and the medium as well as to the chemical stability of the NP surface. Biological response during in vitro assessment was also performed for one given pre-dispersion time condition and demonstrates that the preparation method significantly alters the results. © 2012 Springer Science+Business Media B.V.
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Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Aluminum Alloys Composites Properties · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (42)
Show source-provided references
1. Bae S-T, Shin H, Jung HS, Hong KS (2009) Synthesis of titanium carbide nanoparticles with a high specific surface area from a TiO2 core–sucrose shell precursor. J Am Ceram Soc 92(11):2512–251610.1111/j.1551-2916.2009.03243.x ↗
2. Barillet S, Jugan ML, Laye M, Leconte Y, Herlin-Boime N, Reynaud C, Carrière M (2010) In vitro evaluation of SiC nanoparticles impact on A549 pulmonary cells: Cyto-, genotoxicity and oxidative stress. Toxicol Lett 198(3):324–33010.1016/j.toxlet.2010.07.009 ↗
3. Bihari P, Vippola M, Schultes S, Praetner M, Khandoga A, Reichel C, Coester C, Tuomi T, Rehberg M, Krombach F (2008) Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part Fibre Toxicol 5(1):1410.1186/1743-8977-5-14 ↗
4. Borm P, Robbins D, Haubold S, Kuhlbusch T, Fissan H, Donaldson K, Schins R, Stone V, Kreyling W, Lademann J, Krutmann J, Warheit D, Oberdorster E (2006) The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol 3(1):1110.1186/1743-8977-3-11 ↗
5. Che J, Wang X, Xiao Y, Wu X, Zhou L, Yuan W (2007) Effect of inorganic–organic composite coating on the dispersion of silicon carbide nanoparticles in non-aqueous medium. Nanotechnology 18(13):13570610.1088/0957-4484/18/13/135706 ↗
6. Cherukuri P, Bachilo SM, Litovsky SH, Weisman RB (2004) Near-infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells. J Am Chem Soc 126(48):15638–1563910.1021/ja0466311 ↗
7. Cherukuri P, Gannon CJ, Leeuw TK, Schmidt HK, Smalley RE, Curley SA, Weisman RB (2006) Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence. Proc Natl Acad Sci USA 103(50):18882–18886. doi: 10.1073/pnas.060926510310.1073/pnas.0609265103 ↗
8. Corey JM, Gertz CC, Sutton TJ, Chen Q, Mycek KB, Wang BS, Martin AA, Johnson SL, Feldman EL (2009) Patterning N-type and S-type neuroblastoma cells with Pluronic F108 and ECM proteins. J Biomed Mater Res A 93(2):673–68610.1002/jbm.a.32485 ↗
9. Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG (2000) Human keratinocytes that express hTERT and also bypass a p16INK4a-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Mol Cell Biol 20(4):1436–1447. doi: 10.1128/mcb.20.4.1436-1447.200010.1128/MCB.20.4.1436-1447.2000 ↗
10. Foucaud L, Wilson MR, Brown DM, Stone V (2007) Measurement of reactive species production by nanoparticles prepared in biologically relevant media. Toxicol Lett 174:1–910.1016/j.toxlet.2007.08.001 ↗
11. Fubini B, Ghiazza M, Fenoglio I (2010) Physico-chemical features of engineered nanoparticles relevant to their toxicity. Nanotoxicology 4(4):347–36310.3109/17435390.2010.509519 ↗
12. Fukushima M, Zhou Y, Yoshizawa Y-I (2008) Fabrication and microstructural characterization of porous silicon carbide with nano-sized powders. Mater Sci Eng B 148(1–3):211–21410.1016/j.mseb.2007.09.026 ↗
13. Guevara-Lora I, Czosnek C, Smycz A, Janik J, Kozik A (2009) SiC nanoparticles as potential carriers for biologically active substances. J Phys Conf Ser 146(1):01202210.1088/1742-6596/146/1/012022 ↗
14. Hassan M, Rawat RS, Lee P, Hassan SM, Qayyum A, Ahmad R, Murtaza G, Zakaullah M (2008) Synthesis of nanocrystalline multiphase titanium oxycarbide (TiC x O y ) thin films by UNU/ICTP and NX2 plasma focus devices. Appl Phys A 90(4):669–67710.1007/s00339-007-4335-8 ↗
15. Hoet P, Bruske-Hohlfeld I, Salata O (2004) Nanoparticles—known and unknown health risks. J Nanobiotechnol 2(1):1210.1186/1477-3155-2-12 ↗
16. Iijima M, Kamiya H (2008) Surface modification of silicon carbide nanoparticles by azo radical initiators. J Phys Chem C 112(31):11786–1179010.1021/jp709608p ↗
17. Iolitec (2007a) Silicon(IV)carbide—technical data sheet. http://www.nanomaterials.iolitec.de/en/Nanomaterials/carbide.html . Retrieved 2012-03-19
18. Iolitec (2007b) Titanium(IV)carbide powder—technical data sheet. http://www.nanomaterials.iolitec.de/en/Nanomaterials/carbide.html . Retrieved 2012-03-19
19. Karakoti A, Hench L, Seal S (2006) The potential toxicity of nanomaterials—the role of surfaces. J Manag 58(7):77–82
20. Lee K-H, Lee S-K, Jeon K-S (2009) Photoluminescent properties of silicon carbide and porous silicon carbide after annealing. Appl Surf Sci 255(8):4414–442010.1016/j.apsusc.2008.11.047 ↗
21. Lin H, Gerbec JA, Sushchikh M, McFarland EW (2008) Synthesis of amorphous silicon carbide nanoparticles in a low temperature low pressure plasma reactor. Nanotechnology 19(32):32560110.1088/0957-4484/19/32/325601 ↗
22. Lison D, Thomassen LCJ, Rabolli V, Gonzalez L, Napierska D, Seo JW, Kirsch-Volders M, Hoet P, Kirschhock CEA, Martens JA (2008) Nominal and effective dosimetry of silica nanoparticles in cytotoxicity assays. Toxicol Sci 104(1):155–162. doi: 10.1093/toxsci/kfn07210.1093/toxsci/kfn072 ↗
23. Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA (2008) Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci 105(38):14265–14270. doi: 10.1073/pnas.080513510510.1073/pnas.0805135105 ↗
24. Meißner T, Kühnel D, Busch W, Oswald S, Richter V, Michaelis A, Schirmer K, Potthoff A (2010) Physical–chemical characterization of tungsten carbide nanoparticles as a basis for toxicological investigations. Nanotoxicology 4(2):196–206. doi: 10.3109/1743539100360545510.3109/17435391003605455 ↗
25. Mejia J, Tichelaar F, Saout C, Toussaint O, Bernard M, Mekhalif Z, Lucas S, Delhalle J (2011) Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment. J Nanopart Res 13:655–667. doi: 10.1007/s11051-010-0063-710.1007/s11051-010-0063-7 ↗
26. Merkus HG (2009) Particle size measurements—fundamentals, practice, quality. Particle technology series, vol 17. Springer, Dordrecht, pp 329–334. doi: 978-1-4020-9016-5
27. Monopoli MP, Walczyk D, Campbell A, Elia G, Lynch I, Baldelli Bombelli F, Dawson KA (2011) Physical–chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. J Am Chem Soc 133(8):2525–253410.1021/ja107583h ↗
28. Nel A, Xia T, Madler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622–627. doi: 10.1126/science.111439710.1126/science.1114397 ↗
29. Novak S, Kovac J, Drazic G, Ferreira JMF, Quaresma S (2007) Surface characterisation and modification of submicron and nanosized silicon carbide powders. J Eur Ceram Soc 27(12):3545–355010.1016/j.jeurceramsoc.2007.02.199 ↗
30. Piret JP, Detriche S, Vigneron R, Vankoningsloo S, Rolin S, Mejia Mendoza J, Masereel B, Lucas S, Delhalle J, Luizi F, Saout C, Toussaint O (2010) Dispersion of multi-walled carbon nanotubes in biocompatible dispersants. J Nanopart Res 12(1):75–8210.1007/s11051-009-9697-8 ↗
31. Raman V, Abbas A (2008) Experimental investigations on ultrasound mediated particle breakage. Ultrason Sonochem 15(1):55–6410.1016/j.ultsonch.2006.11.009 ↗
32. Sager TM, Porter DW, Robinson VA, Lindsley WG, Schwegler-Berry DE, Castranova V (2007) Improved method to disperse nanoparticles for in vitro and in vivo investigation of toxicity. Nanotoxicology 1:118–12910.1080/17435390701381596 ↗
33. Shimoda K, Park J-S, Hinoki T, Kohyama A (2007) Influence of surface structure of SiC nano-sized powder analyzed by X-ray photoelectron spectroscopy on basic powder characteristics. Appl Surf Sci 253(24):9450–945610.1016/j.apsusc.2007.06.023 ↗
34. Singh B, Jena J, Besra L, Bhattacharjee S (2007) Dispersion of nano-silicon carbide (SiC) powder in aqueous suspensions. J Nanopart Res 9(5):797–80610.1007/s11051-006-9121-6 ↗
35. Suslick KS, Price GJ (1999) Applications of ultrasound to materials chemistry. Annu Rev Mater Sci 29(1):29510.1146/annurev.matsci.29.1.295 ↗
36. Suslick KS, Didenko Y, Fang MM, Hyeon T, Kolbeck KJ, McNamara WB, Mdleleni MM, Wong M (1999) Acoustic cavitation and its chemical consequences. Philos Trans R Soc Lond A 357(1751):335–353. doi: 10.1098/rsta.1999.033010.1098/rsta.1999.0330 ↗
37. Tartaj P, Reece M, Moya JS (1998) Electrokinetic behavior and stability of silicon carbide nanoparticulate dispersions. J Am Ceram Soc 81(2):389–39410.1111/j.1151-2916.1998.tb02345.x ↗
38. Taurozzi JS, Hackley VA, Wiesner MR (2011) Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment—issues and recommendations. Nanotoxicology 5(4):711–729. doi: 10.3109/17435390.2010.52884610.3109/17435390.2010.528846 ↗
39. Teeguarden JG, Hinderliter PM, Orr G, Thrall BD, Pounds JG (2007) Particokinetics in vitro: dosimetry considerations for in vitro nanoparticle toxicology assessments. Toxicol Sci 97(2):614. doi: 10.1093/toxsci/kfm09710.1093/toxsci/kfm097 ↗
40. Vankoningsloo S, Piret J-P, Saout C, Noel F, Mejia J, Zouboulis CC, Delhalle J, Lucas S, Toussaint O (2010) Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: effects of sonication, dispersive agents and corneous layer of reconstructed epidermis. Nanotoxicology 4(1):84–97. doi: 10.3109/1743539090342886910.3109/17435390903428869 ↗
41. Vauthier C, Cabane B, Labarre D (2008) How to concentrate nanoparticles and avoid aggregation? Eur J Pharm Biopharm 69(2):466–47510.1016/j.ejpb.2008.01.025 ↗
42. Yates PD, Franks GV, Jameson GJ (2008) Orthokinetic heteroaggregation with nanoparticles: effect of particle size ratio on aggregate properties. Colloid Surf A 326(1–2):83–9110.1016/j.colsurfa.2008.05.030 ↗