A comparative study of three different synthesis routes for hydrophilic fluorophore-doped silica nanoparticles
Source abstract
Abstract
The synthesis of fluorophore-doped silica nanoparticles (FDS NPs) with two conventional approaches, Stober and microemulsion, as well as a novel amino acid-catalyzed seeds regrowth technique (ACSRT) is presented. The efficiency of each applied synthesis route toward incorporation of selected hydrophilic fluorophores, including rhodamine B isothiocyanate and fluorescein isothiocyanate, without and with an amine-containing crosslinker, into silica matrix was systematically studied. Our results clearly highlight the advantages of ACSRT to obtain FDS NPs with a remarkable encapsulation efficiency, high quantum yield, and enhanced stability against bleaching and dye leaking due to efficient embedding of the dyes inside silica network even without the amine-containing silane reagent. Moreover, evaluation of photostability of FDNPs internalized in human bone cells demonstrates the merits of ACSRT.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Porphyrin and Phthalocyanine Chemistry · Mesoporous Materials and Catalysis · Luminescence and Fluorescent Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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