Evaluation of nano-specific toxicity of zinc oxide, copper oxide, and silver nanoparticles through toxic ratio
Source abstract
Abstract
For safety and environmental risk assessments of nanomaterials (NMs) and to provide essential toxicity data, nano-specific toxicities, or excess toxicities, of ZnO, CuO, and Ag nanoparticles (NPs) (20, 20, and 30 nm, respectively) to Escherichia coli and Saccharomyces cerevisiae in short-term (6 h) and long-term (48 h) bioassays were quantified based on a toxic ratio. ZnO NPs exhibited no nano-specific toxicities, reflecting similar toxicities as ZnO bulk particles (BPs) (as well as zinc salt). However, CuO and Ag NPs yielded distinctly nano-specific toxicities when compared with their BPs. According to their nano-specific toxicities, the capability of these NPs in eliciting hazardous effects on humans and the environment was as follows: CuO > Ag > ZnO NPs. Moreover, long-term bioassays were more sensitive to nano-specific toxicity than short-term bioassays. Overall, nano-specific toxicity is a meaningful measurement to evaluate the environmental risk of NPs. The log T e particle value is a useful parameter for quantifying NP nano-specific toxicity and enabling comparisons of international toxicological data. Furthermore, this value could be used to determine the environmental risk of NPs.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Microplastics and Plastic Pollution · Healthcare and Environmental Waste Management
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (48)
Show source-provided references
1. Aruoja V, Dubourguier H-C, Kasemets K, Kahru A (2009) Toxicity of nanoparticles of CuO, ZnO and TiO2 to microalgae Pseudokirchneriella subcapitata. Sci Total Environ 407:1461–1468. doi: 10.1016/j.scitotenv.2008.10.05310.1016/j.scitotenv.2008.10.053 ↗
2. Bai C, Liu M (2013) From chemistry to nanoscience: not just a matter of size. Angew Chem Int Ed 52:2678–2683. doi: 10.1002/anie.20121005810.1002/anie.201210058 ↗
3. Bao S, Lu Q, Fang T, Dai H, Zhang C (2015) An assessment of the toxicity of CuO nanoparticles using multiple-gene-deleted mutants of Saccharomyces cerevisiae. Appl Environ Microb. doi: 10.1128/aem.02035-1510.1128/aem.02035-15 ↗
4. Bian S-W, Mudunkotuwa IA, Rupasinghe T, Grassian VH (2011) Aggregation and dissolution of 4 nm ZnO nanoparticles in aqueous environments: influence of pH, ionic strength, size, and adsorption of humic acid. Langmuir 27:6059–6068. doi: 10.1021/la200570n10.1021/la200570n ↗
5. Bondarenko O, Juganson K, Ivask A, Kasemets K, Mortimer M, Kahru A (2013) Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review. Arch Toxicol 87:1181–1200. doi: 10.1007/s00204-013-1079-410.1007/s00204-013-1079-4 ↗
6. Brayner R, Ferrari-Iliou R, Brivois N, Djediat S, Benedetti MF, Fiévet F (2006) Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium. Nano Lett 6:866–870. doi: 10.1021/nl052326h10.1021/nl052326h ↗
7. Burello E (2015) Computational design of safer nanomaterials. Environ. Sci. Nano. 2:454–462. doi: 10.1039/c5en00066a10.1039/c5en00066a ↗
8. Buzea C, Pacheco II, Robbie K (2007) Nanomaterials and nanoparticles: sources and toxicity. Biointerphases 2:MR17–MR7110.1116/1.2815690 ↗
9. Donaldson K, Poland CA (2013) Nanotoxicity: challenging the myth of nano-specific toxicity. Curr Opin Biotechnol 24:724–734. doi: 10.1016/j.copbio.2013.05.00310.1016/j.copbio.2013.05.003 ↗
10. Donaldson K, Stone V, Tran CL, Kreyling W, Borm PJA (2004) Nanotoxicology. J Occup Environ Med 61:727–728. doi: 10.1136/oem.2004.01324310.1136/oem.2004.013243 ↗
11. Gajewicz A, Rasulev B, Dinadayalane TC, Urbaszek P, Puzyn T, Leszczynska D, Leszczynski J (2012) Advancing risk assessment of engineered nanomaterials: application of computational approaches. Adv Drug Deliv Rev 64:1663–1693. doi: 10.1016/j.addr.2012.05.01410.1016/j.addr.2012.05.014 ↗
12. Garner KL, Suh S, Lenihan HS, Keller AA (2015) Species sensitivity distributions for engineered nanomaterials. Environ. Sci. Technol. 49:5753–5759. doi: 10.1021/acs.est.5b0008110.1021/acs.est.5b00081 ↗
13. Golbamaki N, Rasulev B, Cassano A, Marchese Robinson RL, Benfenati E, Leszczynski J, Cronin MTD (2015) Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms. Nanoscale 7:2154–2198. doi: 10.1039/c4nr06670g10.1039/c4nr06670g ↗
14. Gong J, Zhou F, Li Z, Tang Z (2012) Synthesis of Au@Ag core–shell nanocubes containing varying shaped cores and their localized surface plasmon resonances. Langmuir 28:8959–8964. doi: 10.1021/la204684u10.1021/la204684u ↗
15. He L, Liu Y, Liu J, Xiong Y, Zheng J, Liu Y, Tang Z (2013) Core–shell noble-metal@metal-organic-framework nanoparticles with highly selective sensing property. Angew Chem Int Ed 52:3741–3745. doi: 10.1002/anie.20120990310.1002/anie.201209903 ↗
16. He X, Aker WG, Fu PP, Hwang H-M (2015) Toxicity of engineered metal oxide nanomaterials mediated by nano-bio-eco-interactions: a review and perspective. Environ. Sci. Nano. doi: 10.1039/c5en00094g10.1039/c5en00094g ↗
17. Heinlaan M, Ivask A, Blinova I, Dubourguier H-C, Kahru A (2008) Toxicity of nanosized and bulk ZnO, CuO and TiO2 to bacteria Vibrio fischeri and crustaceans Daphnia magna and Thamnocephalus platyurus. Chemosphere 71:1308–1316. doi: 10.1016/j.chemosphere.2007.11.04710.1016/j.chemosphere.2007.11.047 ↗
18. Huang Z et al (2008) Toxicological effect of ZnO nanoparticles based on bacteria. Langmuir 24:4140–4144. doi: 10.1021/la703594910.1021/la7035949 ↗
19. Ivask A, Bondarenko O, Jepihhina N, Kahru A (2010) Profiling of the reactive oxygen species-related ecotoxicity of CuO, ZnO, TiO2, silver and fullerene nanoparticles using a set of recombinant luminescent Escherichia coli strains: differentiating the impact of particles and solubilised metals. Anal Bioanal Chem 398:701–716. doi: 10.1007/s00216-010-3962-710.1007/s00216-010-3962-7 ↗
20. Ivask A et al (2014a) Toxicity mechanisms in Escherichia coli vary for silver nanoparticles and differ from ionic silver. ACS Nano 8:374–386. doi: 10.1021/nn404404710.1021/nn4044047 ↗
21. Ivask A et al (2014b) Mechanisms of toxic action of Ag, ZnO and CuO nanoparticles to selected ecotoxicological test organisms and mammalian cells in vitro: a comparative review. Nanotoxicology 8:57–71. doi: 10.3109/17435390.2013.85583110.3109/17435390.2013.855831 ↗
22. Kahru A, Dubourguier H-C (2010) From ecotoxicology to nanoecotoxicology. Toxicology 269:105–119. doi: 10.1016/j.tox.2009.08.01610.1016/j.tox.2009.08.016 ↗
23. Kasemets K, Ivask A, Dubourguier H-C, Kahru A (2009) Toxicity of nanoparticles of ZnO, CuO and TiO2 to yeast Saccharomyces cerevisiae. Toxicol in Vitro 23:1116–1122. doi: 10.1016/j.tiv.2009.05.01510.1016/j.tiv.2009.05.015 ↗
24. Kaweeteerawat C et al (2015) Toxicity of metal oxide nanoparticles in Escherichia coli correlates with conduction band and hydration energies. Environ. Sci. Technol. 49:1105–1112. doi: 10.1021/es504259s10.1021/es504259s ↗
25. Kleandrova VV, Luan F, González-Díaz H, Ruso JM, Speck-Planche A, Cordeiro MNDS (2014) Computational tool for risk assessment of nanomaterials: novel QSTR-perturbation model for simultaneous prediction of ecotoxicity and cytotoxicity of uncoated and coated nanoparticles under multiple experimental conditions. Environ. Sci. Technol. 48:14686–14694. doi: 10.1021/es503861x10.1021/es503861x ↗
26. Li K, Chen Y, Zhang W, Pu Z, Jiang L, Chen Y (2012) Surface interactions affect the toxicity of engineered metal oxide nanoparticles toward paramecium. Chem Res Toxicol 25:1675–1681. doi: 10.1021/tx300151y10.1021/tx300151y ↗
27. Li M, Zhu L, Lin D (2011) Toxicity of ZnO nanoparticles to Escherichia coli: mechanism and the influence of medium components. Environ. Sci. Technol. 45:1977–1983. doi: 10.1021/es102624t10.1021/es102624t ↗
28. Li Y, Niu J, Zhang W, Zhang L, Shang E (2014) Influence of aqueous media on the ROS-mediated toxicity of ZnO nanoparticles toward green fluorescent protein-expressing Escherichia coli under UV-365 irradiation. Langmuir 30:2852–2862. doi: 10.1021/la500002810.1021/la5000028 ↗
29. Magdolenova Z, Collins A, Kumar A, Dhawan A, Stone V, Dusinska M (2014) Mechanisms of genotoxicity. A review of in vitro and in vivo studies with engineered nanoparticles. Nanotoxicology 8:233–278. doi: 10.3109/17435390.2013.77346410.3109/17435390.2013.773464 ↗
30. McCracken C, Dutta P, Waldman WJ (2016) Critical assessment of toxicological effects of ingested nanoparticles. Environ Sci: Nano. doi: 10.1039/c5en00242g10.1039/c5en00242g ↗
31. Mortimer M, Kasemets K, Kahru A (2010) Toxicity of ZnO and CuO nanoparticles to ciliated protozoa Tetrahymena thermophila. Toxicology 269:182–189. doi: 10.1016/j.tox.2009.07.00710.1016/j.tox.2009.07.007 ↗
32. Pettibone J, Louie S (2015) Research highlights: towards further understanding nanoparticle-cellular membrane interactions. Environ. Sci. Nano. 2:664–668. doi: 10.1039/c5en90024g10.1039/c5en90024g ↗
33. Qin B, Zhao Z, Song R, Shanbhag S, Tang Z (2008) A temperature-driven reversible phase transfer of 2-(diethylamino)ethanethiol-stabilized CdTe nanoparticles. Angew Chem Int Ed 47:9875–9878. doi: 10.1002/anie.20080358210.1002/anie.200803582 ↗
34. Schramm F, Müller A, Hammer H, Paschke A, Schüürmann G (2011) Epoxide and thiirane toxicity in vitro with the ciliates Tetrahymena pyriformis: structural alerts indicating excess toxicity. Environ. Sci. Technol. 45:5812–5819. doi: 10.1021/es200081n10.1021/es200081n ↗
35. Studer AM et al (2010) Nanoparticle cytotoxicity depends on intracellular solubility: comparison of stabilized copper metal and degradable copper oxide nanoparticles. Toxicol Lett 197:169–174. doi: 10.1016/j.toxlet.2010.05.01210.1016/j.toxlet.2010.05.012 ↗
36. von Moos N, Bowen P, Slaveykova VI (2014) Bioavailability of inorganic nanoparticles to planktonic bacteria and aquatic microalgae in freshwater. Environ Sci Nano 1:214–232. doi: 10.1039/c3en00054k10.1039/c3en00054k ↗
37. Wang Z, Chen J, Li X, Shao J, Peijnenburg WJGM (2012a) Aquatic toxicity of nanosilver colloids to different trophic organisms: contributions of particles and free silver ion. Environ Toxicol Chem 31:2408–2413. doi: 10.1002/etc.196410.1002/etc.1964 ↗
38. Wang Z, Li N, Zhao J, White JC, Qu P, Xing B (2012b) CuO nanoparticle interaction with human epithelial cells: cellular uptake, location, export, and genotoxicity. Chem Res Toxicol 25:1512–1521. doi: 10.1021/tx300209310.1021/tx3002093 ↗
39. Xiao Y, Vijver MG, Chen G, Peijnenburg WJGM (2015) Toxicity and accumulation of Cu and ZnO nanoparticles in Daphnia magna. Environ. Sci. Technol. 49:4657–4664. doi: 10.1021/acs.est.5b0053810.1021/acs.est.5b00538 ↗
40. Xiong D, Fang T, Yu L, Sima X, Zhu W (2011) Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damage. Sci Total Environ 409:1444–1452. doi: 10.1016/j.scitotenv.2011.01.01510.1016/j.scitotenv.2011.01.015 ↗
41. Xiu Z-m, Zhang Q-b, Puppala HL, Colvin VL, Alvarez PJJ (2012) Negligible particle-specific antibacterial activity of silver nanoparticles. Nano Lett 12:4271–4275. doi: 10.1021/nl301934w10.1021/nl301934w ↗
42. Yang H, Liu C, Yang D, Zhang H, Xi Z (2009) Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition. Appl Toxicol 29:69–78. doi: 10.1002/jat.138510.1002/jat.1385 ↗
43. Yu L-p, Fang T, Xiong D-w, Zhu W-t, Sima X-f (2011) Comparative toxicity of nano-ZnO and bulk ZnO suspensions to zebrafish and the effects of sedimentation, OH production and particle dissolution in distilled water. J Environ Monit 13:1975–198210.1039/c1em10197h ↗
44. Zhang W, Bao S, Fang T (2016) The neglected nano-specific toxicity of ZnO nanoparticles in the yeast Saccharomyces cerevisiae. Sci Rep 6:24839. doi: 10.1038/srep24839http://www.nature.com/articles/srep24839#supplementary-information10.1038/srep24839http://www.nature.com/articles/srep24839#supplementary-information ↗
45. Zhang W, Yao Y, Sullivan N, Chen Y (2011) Modeling the primary size effects of citrate-coated silver nanoparticles on their ion release kinetics. Environ Sci Technol 45:4422–4428. doi: 10.1021/es104205a10.1021/es104205a ↗
46. Zhou Y, Yang M, Sun K, Tang Z, Kotov NA (2010) Similar topological origin of chiral centers in organic and nanoscale inorganic structures: effect of stabilizer chirality on optical isomerism and growth of CdTe nanocrystals. J Am Chem Soc 132:6006–6013. doi: 10.1021/ja906894r10.1021/ja906894r ↗
47. Zhou Y et al (2011) Optical coupling between chiral biomolecules and semiconductor nanoparticles: size-dependent circular dichroism absorption. Angew Chem Int Ed 50:11456–11459. doi: 10.1002/anie.20110376210.1002/anie.201103762 ↗
48. Zhu Z et al (2011) Superstructures and SERS properties of gold nanocrystals with different shapes. Angew Chem Int Ed 50:1593–1596. doi: 10.1002/anie.20100549310.1002/anie.201005493 ↗