Zinc oxide nanowires-based electrochemical biosensor for L-lactic acid amperometric detection
Source abstract
Abstract
In this work, zinc oxide (ZnO) nanowires-based electrochemical biosensor is designed and fabricated for the detection of L-lactic acid. ZnO nanowires were successfully synthesized via the chemical vapor deposition method. The morphology and structure of the prepared products were characterized, and the average diameter of synthesized ZnO samples was 500 nm. The fluorescence characterization was performed to verify the immobilization of lactate oxidase onto the ZnO surface. Biosensors based on large-area ZnO nanowires were then constructed, and a series of electrochemical experiments showed that ZnO could provide the efficient electron transfer channel between the enzymic active sites and the electrode surface. The proposed electrochemical biosensor exhibited a sensitivity of 15.6 µA cm−2 mM−1, a wide linear range of 12 µM–1.2 mM with a low-detection limit of 12 µM for L-lactic acid detection. This study has indicated the potential applications for ZnO nanowires to construct the simple and economic nano-bio devices for the detection of biological species.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Electrochemical sensors and biosensors · Advanced biosensing and bioanalysis techniques · Electrochemical Analysis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (37)
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