journal article·1999-09

Measurement of the Density of Polymeric Nanoparticulate Drug Carriers by Isopycnic Centrifugation

C. Vauthier, C. Schmidt, P. Couvreur

Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Field-Flow Fractionation Techniques · Protein purification and stability

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (18)

Show source-provided references
1. Chouinard F., S. Buczkowski & V. Lenaerts 1994. Polyalkylcyanoacrylate nanocapsules: Physicochemical characterization and mechanism of formation. Pharm. Res. 11, 869–874.10.1023/A:1018938026615 ↗
2. Colin deVerdière A., C. Dubernet, F. Nemati, E. Soma, M. Appel, J. Ferte, S. Bernard, F. Puisieux & P. Couvreur, 1997. Reversion of the multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action. British Journal of Cancer 76, 198–205.10.1038/bjc.1997.362 ↗
3. Couvreur P., B. Kante, M. Roland, P. Guiot, P. Baudhuin & P. Speiser, 1979. Polyalkylcyanoacrylate nanocapsules as potential lysosomotropic carriers: preparation, morphological and sorptive properties. J. Pharm. Pharmacol. 31, 331–332.10.1111/j.2042-7158.1979.tb13510.x ↗
4. Couvreur P. & C. Vauthier, 1994. Nanoparticles: therapeutic application and prospects. In: A.G. de Boer, ed. Drug Absorption Enhancement, Harwood Academic Publishers gmbh, Chur, Switzerland, pp. 457–486.
5. De Duve C., 1975. Exploring cells with a centrifuge. Science 189, 186–194.10.1126/science.1138375 ↗
6. Fattal E., C. Vauthier, I. Aynié, Y. Nakada, G. Lambert, C. Malvy & P. Couvreur, 1998. Biodegradable polyalkylcyanoacrylate nanoparticles for the delivery of oligonucleotides. J. Controll. Rel. 53, 137–143.10.1016/S0168-3659(97)00246-0 ↗
7. Fessi H., F. Puisieux & J.P. Devissaguet, 1988. Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles. US Patent No. 5,118,528.
8. Fritsch A., 1975. Les centrifugations préparatives en gradient de densité. 2nd Edition, Beckman Instruments France, Chap. 3, pp. 91–146.
9. Huve P., T. Verrecchia, D. Bazile, C. Vauthier & P. Couvreur, 1994. Simultaneous use of size-exclusion chromatography and photon correlation spectroscopy for the characterization of poly(lactic acid) nanoparticles. J. Chromatography A 675, 129–139.10.1016/0021-9673(94)85267-7 ↗
10. Irache J., C. Durrer, G. Ponchel & D. Duchene, 1993. Determination of particle concentration in latexes by turbidimetry. Int. J. Pharm. 90, R9–R12.10.1016/0378-5173(93)90203-R ↗
11. Kattan J., J.P. Droz, P. Couvreur, J.P. Marino, A. Boutan-Laroze, P. Rougier, P. Brault, H. Vrancks, J.M. Grognet, X. Morge & H. Sancho-Garnier, 1992. Phase I clinical trial and pharmacokinetic evaluation of doxorubicin carried by polyisohexylcyanoacrylate nanoparticles. Invest. New Drugs 10, 191–199.10.1007/BF00877245 ↗
12. Kreuter J., 1983. Physicochemical characterization of polyacrylic nanoparticles. Int. J. Pharm. 14, 43–58.10.1016/0378-5173(83)90113-8 ↗
13. Mc Graw-Hill, 1992. Centrifugation. In: Encyclopedia of Sciences and Technology, Mc Graw-Hill Inc., New York, Saint-Louis, San Francisco, USA, Vol. 3, pp. 412–419.
14. Nemati F., C. Dubernet, A. Colin de Verdière, M.F. Poupon, L. Treupel-Acar, F. Puisieux & P. Couvreur, 1994. Cytotoxicity of free doxorubicin and doxoribicin-loaded nanoparticles in sensitive and multidrug resistant leucemic murine cells: incubation time, number of nanoparticles per cell. Int. J. of Pharm. 102, 55–62.10.1016/0378-5173(94)90039-6 ↗
15. Rickwood D.,T. Ford & J. Steensgaard, 1994. Methods for preparing gradients. In Centrifugation Essential Data. JohnWiley and Sons, Inc., Huddersfield, UK, Chap. 8, pp. 56–64.
16. Rudd J.F., 1974. Physical constants of polystyrene. In: Polymer Handbook, 2nd Edition. Bandrup J. and Immergut E.H. eds. John Wiley and Sons Inc., New York, USA, p.V 59.
17. Schwab G., C. Chavany, I. Duroux, G. Goubin, J. Lebeau, C.Hélène & T.S. Behmoaras, 1994. Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticules specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice. Proc. Natl. Acad. Sci. USA 91, 10460–10464.10.1073/pnas.91.22.10460 ↗
18. Vittaz M., D. Bazile, G. Spenlehauer, T. Verrecchia, M. Veillard, F. Puisieux & D. Labarre, 1996. Effect of PEO surface density on long-circulating PLA–POE nanoparticles which are very low complement activators. Biomaterials 17, 1575–1581.10.1016/0142-9612(95)00322-3 ↗