DataVXJournal of Nanoparticle ResearchPaper
journal article·2026-03

Research progress on detecting tetracycline antibiotic residues in food using fluorescence sensors

Ying Wang, Hua Wang, Lei Zhu, Jinneng Wang, Zeyan Xie, Haifeng Yang, Yukou Du

Journal of Nanoparticle Research· Volume 28· Issue 3
Publisher page
Bibliographic record

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Pharmaceutical and Antibiotic Environmental Impacts · Biosensors and Analytical Detection · Melamine detection and toxicity

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (65)

Show source-provided references
1. Messele YE, Werid GM, Petrovski K (2023) Meta-analysis on the global prevalence of tetracycline resistance in Escherichia coli isolated from beef cattle. Vet Sci 10(7):479. https://doi.org/10.3390/vetsci1007047910.3390/vetsci10070479 ↗
2. Marrugo-Padilla A, Mendez-Cuadro D, Rodriguez-Cavallo E (2022) Tetracycline residues induce carbonylation of milk proteins and alter their solubility and digestibility. Int Dairy J 125:105226. https://doi.org/10.1016/j.idairyj.2021.10522610.1016/j.idairyj.2021.105226 ↗
3. Gab-Allah MA, Lijalem YG, Yu H, Lim DK, Ahn S, Choi K, Kim B (2023) Accurate determination of four tetracycline residues in chicken meat by isotope dilution-liquid chromatography/tandem mass spectrometry. J Chromatogr A 1691:463818. https://doi.org/10.1016/j.chroma.2023.46381810.1016/j.chroma.2023.463818 ↗
4. Sørensen L, Schaufelberger S, Igartua A, Størseth TR, Øverjordet IB (2022) Non-target and suspect screening reveal complex pattern of contamination in Arctic marine zooplankton. Sci Total Environ 864:161056. https://doi.org/10.1016/j.scitotenv.2022.16105610.1016/j.scitotenv.2022.161056 ↗
5. Ozdemir Olgun FA, Demirata B (2020) Evaluation of tetracycline, oxytetracycline and penicillin G residues in chicken meat samples by high performance liquid chromatography with pda detection. Cumhur Sci J 41(3):665–67010.17776/csj.723599 ↗
6. Wang G, Zhang HC, Liu J, Wang JP (2019) A receptor-based chemiluminescence enzyme linked immunosorbent assay for determination of tetracyclines in milk. Anal Biochem 564:40–46. https://doi.org/10.1016/j.ab.2018.10.01710.1016/j.ab.2018.10.017 ↗
7. Lopes CEC, de Faria LV, Araújo DAG, Richter EM, Paixão TRLC, Dantas LMF, Muñoz RAA, da Silva IS (2023) Lab-made 3D-printed electrochemical sensors for tetracycline determination. Talanta 259:124536. https://doi.org/10.1016/j.talanta.2023.12453610.1016/j.talanta.2023.124536 ↗
8. Wang Y, Zhang K, Du Y (2022) Recent progress of carbon dot fluorescent probes for tetracycline detection. New J Chem 46(43):20554–20560. https://doi.org/10.1039/D2NJ04064F10.1039/D2NJ04064F ↗
9. Tian XX, Zheng XC, Chen L, Wang ZY, Liu BT, Bi YZ, Li L, Shi HN, Li SB, Li C, Zhang DQ (2024) Recent advances in photoluminescent fluorescent probe technology for food flavor compounds analysis. Food Chem 459:140455. https://doi.org/10.1016/j.foodchem.2024.14045510.1016/j.foodchem.2024.140455 ↗
10. He HY, Sun DW, Wu ZH, Pu HB, Wei QY (2022) On-off-on fluorescent nanosensing: materials, detection strategies and recent food applications. Trends Food Sci Technol 119:243–256. https://doi.org/10.1016/j.tifs.2021.11.02910.1016/j.tifs.2021.11.029 ↗
11. Wang Q, Cheng Y, Ding LF, Zhang XR, Li SL, Zhang J, Niu YL, Dong C, Shuang SM (2024) Chinese food seasoning derived carbon dots for highly selective detection of Fe3+and smartphone-based dual-color fluorescence ratiometric visualization sensing. J Mol Struct 1318:139209. https://doi.org/10.1016/j.molstruc.2024.13920910.1016/j.molstruc.2024.139209 ↗
12. Yang XS, Wang LL, Zhao J, Ji SL, Liu QW, Peng XY, Hu ZH, Liu YS, Wang P (2023) Construction of fluorescent copper nanoclusters for selective sensing Fe3+ in food samples based on absorption competition quenching mechanism. J Food Meas Charact 17:2850–2857. https://doi.org/10.1007/s11694-023-01828-510.1007/s11694-023-01828-5 ↗
13. Guan JP, He Q, Liu Q, Chen XQ (2023) Cu2+assisted carnation-like fluorescent metal-organic framework for triple-mode detection of glyphosate in food samples. Food Chem 408:135237. https://doi.org/10.1016/j.foodchem.2022.13523710.1016/j.foodchem.2022.135237 ↗
14. Luo XL, Han Y, Chen XM, Tang WZ, Yue TL, Li ZH (2020) Carbon dots derived fluorescent nanosensors as versatile tools for food quality and safety assessment: a review. Trends Food Sci Technol 95:149–161. https://doi.org/10.1016/j.tifs.2019.11.01710.1016/j.tifs.2019.11.017 ↗
15. Mahajan MR, Shaha SN, Nangare SN, Dhole RS, Sugandhi VV, Patil PO, Paudel KR (2026) Fluorescent metal nanoclusters for food safety: advances, challenges, and future perspectives in contaminant detection. Food Chem 500:147439. https://doi.org/10.1016/j.foodchem.2025.14743910.1016/j.foodchem.2025.147439 ↗
16. Wu GJ, Qiu HM, Liu X, Luo PJ, Wu YN, Shen YZ (2023) Nanomaterials-based fluorescent assays for pathogenic bacteria in food-related matrices. Trends Food Sci Technol 142:104214. https://doi.org/10.1016/j.tifs.2023.10421410.1016/j.tifs.2023.104214 ↗
17. Song C, Tao HJ, Sun ZW, Du MM, Sun ZJ (2024) Research progress in detection of heavy metal ions using carbon dots-based fluorescence sensors. Chin J Anal Chem 52:1640–1650. https://doi.org/10.1016/S1872-2040(21)60083-X10.1016/S1872-2040(21)60083-X ↗
18. Xie XY, Huang TR, Huang M (2024) Research progress in the application of carbon dot-based fluorescent aptamer sensors in food safety detection. Food Sci 45(22):361–372
19. Guo YY, Zhang X, Gao P, Tian YF, Dang MM, Yang P (2025) Research progress on the preparation of doped carbon dots and their application in biodetection and bioimaging. New Chem Mater 53(5):226–237
20. Wang SJ, Wang YB, Ning YN, Liu QM (2023) Inner filter effect-based near-infrared fluorescent probe for detection of metronidazole on a smartphone-integrated analytical platform. Analyst 148:2544–2552. https://doi.org/10.1039/D3AN00039G10.1039/D3AN00039G ↗
21. Wang T, Zhang JY, Wu Y, Wang SY, Jiang XH, Zhang ZW, Li SQ (2023) Smartphone-integrated ratiometric fluorescence sensing platform based on bimetallic metal-organic framework nanowires for anthrax biomarker detection. Microchim Acta 190:138048. https://doi.org/10.1016/j.cplett.2020.13804810.1016/j.cplett.2020.138048 ↗
22. Yu Y, Ni W, Hu Q, Y Y, Huang H, Li F, Han J (2024) A dual fluorescence turn‐on sensor array formed by poly(para‐aryleneethynylene) and aggregation‐induced emission fluorophores for sensitive multiplexed bacterial recognition. Angew Chem 136(16):e202318483. https://doi.org/10.1002/ange.20231848310.1002/ange.202318483 ↗
23. Madni A, Zhang Y, Zhang L, Qiang Y, Qi S, Zhai H (2025) Turn “on-off” fluorometric probe based on Sm3+ ions activated gold nanoclusters for tetracycline determination in food samples. J Food Compos Anal 148:108429. https://doi.org/10.1016/j.jfca.2025.10842910.1016/j.jfca.2025.108429 ↗
24. de Silva AP (2022) Crossing the divide: experiences of taking fluorescent PET (photoinduced electron transfer) sensing/switching systems from solution to solid. Dyes Pigments 204:110453. https://doi.org/10.1016/j.dyepig.2022.11045310.1016/j.dyepig.2022.110453 ↗
25. Xu M, Song N, Qiu D, Li X, Liu Y, Yang L, Zhang D, Zhou Z (2024) A porous and chemical stable Co(II)-based metal-organic framework for the selective fluorescence sensing of Fe3+ and tetracycline. J Solid State Chem 332:124562. https://doi.org/10.1016/j.jssc.2024.12456210.1016/j.jssc.2024.124562 ↗
26. Miao S, Liang K, Kong B (2020) Förster resonance energy transfer (FRET) paired carbon dot-based complex nanoprobes: versatile platforms for sensing and imaging applications. Mater Chem Front 4(1):128–139. https://doi.org/10.1039/C9QM00538B10.1039/C9QM00538B ↗
27. Lu X, Gao Q, Xu L, Ren Y, Tong F, Wang Y, Wang L, Ge N, Ge W (2025) Rapid determination of tetracycline utilizing a ratiometric fluorescence with Co-doped carbon quantum dots. J Food Compos Anal 140:107252. https://doi.org/10.1016/j.jfca.2025.10725210.1016/j.jfca.2025.107252 ↗
28. Wu Y, Ge C, Zhang Y, Wang Y, Zhang D (2023) ICT-based fluorescent probes for intracellular pH and biological species detection. Front Chem 11:1304531. https://doi.org/10.3389/fchem.2023.130453110.3389/fchem.2023.1304531 ↗
29. Yin Y, Zhang J, Ji C, Zhao Z, Wang X, Wang P, Yang Y (2025) Flexible silver-metal-organic framework probe for highly sensitive and visual detection of tetracycline hydrochloride in freshwater fish. Talanta 294:128200. https://doi.org/10.1016/j.talanta.2025.12820010.1016/j.talanta.2025.128200 ↗
30. S S, K D, B S, K T (2018) Fluorescence analysis: from sensing to imaging. J Anal Methods Chem 2018:1–2. https://doi.org/10.1155/2018/265412710.1155/2018/2654127 ↗
31. Dong H, Zheng L, Wang M, Zhao L, Xu K, Zhou Y, Zhang Y, Xu MT (2023) Two-photon carbon quantum dots for detection of chlortetracycline in foods. ACS Appl Nano Mater 6(20):19168–19175. https://doi.org/10.1021/acsanm.3c0363510.1021/acsanm.3c03635 ↗
32. Li L, Shi L, Jia J, Eltayeb O, Lu W, Tang Y, Dong C, Shuang S (2021) Red fluorescent carbon dots for tetracycline antibiotics and pH discrimination from aggregation-induced emission mechanism. Sens Actuators B Chem 332:125913. https://doi.org/10.1016/j.snb.2021.12951310.1016/j.snb.2021.129513 ↗
33. Liu Y, Liu B, Huang P, Wu FY, Ma L (2021) Concentration-dependent photoluminescence carbon dots for visual recognition and detection of three tetracyclines[J]. Anal Bioanal Chem 413(9):2565–2575. https://doi.org/10.1007/s00216-021-03221-x10.1007/s00216-021-03221-x ↗
34. Hu F, Fu Q, Li Y, Yan C, Xiao D, Ju P, Hu Z, Li H, Ai S (2023) Zinc-doped carbon quantum dots-based ratiometric fluorescence probe for rapid, specific, and visual determination of tetracycline hydrochloride. Food Chem 431:137097. https://doi.org/10.1142/S179360472451008110.1142/S1793604724510081 ↗
35. Li CY, Zhao ZJ, Bai WQ, Gao LJ (2024) A ratiometric fluorescence sensing system based on Eu3+-bio⁃mass carbon dot probe for the detection of tetracycline hydrochloride. J Instrum Anal 43(4):600–606
36. Fan YJ, Su M, Shi YE, Liu XT, Shen SG, Dong JX (2022) A ratiometric fluorescent sensor for tetracyclines detection in meat based on pH-dependence of targets with lanthanum-doped carbon dots as probes. Anal Bioanal Chem 414:2597–2606. https://doi.org/10.1007/s00216-022-03895-x10.1007/s00216-022-03895-x ↗
37. Li FT, Wang ZK, Zhou Y, Li LZ, Liu YQ, Wang L, Li CL, Zhu HF, Sun SQ, Hu SQ (2023) Improvement of carbon dots corrosion inhibition by ionic liquid modification: experimental and computational investigations. Corros Sci 224:111541. https://doi.org/10.1016/j.corsci.2023.11154110.1016/j.corsci.2023.111541 ↗
38. Wang Q, Sun Y, Zhao A, Cai X, Yu A, Xu Q, Liu W, Zhang N, Wu S, Chen Y, Wang W (2023) High dietary copper intake induces perturbations in the gut microbiota and affects host ovarian follicle development. Ecotoxicol Environ Saf 255:114810. https://doi.org/10.1016/j.ecoenv.2023.11481010.1016/j.ecoenv.2023.114810 ↗
39. Xu J, Cui K, Gong T, Zhang J, Zhai Z, Hou L, Zaman uz F, Yuan C (2022) Ultrasonic-assisted synthesis of N-doped, multicolor carbon dots toward fluorescent inks, fluorescence sensors, and logic gate operations. Nanomaterials 12(3):312. https://doi.org/10.3390/nano1203031210.3390/nano12030312 ↗
40. Liu JX, Li W, Li JY (2025) Hydrogel-involved portable ratiometric fluorescence sensor based on Eu3+/CDs-modified metal-organic framework for detection of ofloxacin and tetracycline. Sens Actuators B Chem 422:136573. https://doi.org/10.1016/j.snb.2024.13657310.1016/j.snb.2024.136573 ↗
41. Zhao Z, Guo Y, Zhang T, Ma J, Li H, Zhou J, Wang Z, Sun R (2020) Preparation of carbon dots from waste cellulose diacetate as a sensor for tetracycline detection and fluorescence ink. Int J Biol Macromol 164:4289–4298. https://doi.org/10.1016/j.ijbiomac.2020.08.24310.1016/j.ijbiomac.2020.08.243 ↗
42. Deng YX, Long YY, Song A, Wang HY, Xiang S, Qiu Y, Ge XY, Golberg D, Weng Q (2023) Boron dopants in red-emitting B and N co-doped carbon quantum dots enable targeted imaging of lysosomes. ACS Appl Mater Interfaces 15(13):17045–17053. https://doi.org/10.1021/acsami.3c0170510.1021/acsami.3c01705 ↗
43. Soni H, Pamidimukkala PS (2018) Green synthesis of N, S co-doped carbon quantum dots from triflic acid treated palm shell waste and their application in nitrophenol sensing. Mater Res Bull 108:250–254. https://doi.org/10.1016/j.materresbull.2018.08.03310.1016/j.materresbull.2018.08.033 ↗
44. Wei W, He J, Wang Y, Kong M (2019) Ratiometric method based on silicon nanodots and Eu3+ system for highly-sensitive detection of tetracyclines. Talanta 204:491–498. https://doi.org/10.1016/j.talanta.2019.06.03610.1016/j.talanta.2019.06.036 ↗
45. Yonesato K, Yanai D, Yamazoe S, Yokogawa D, Kikuchi T, Yamaguchi K, Suzuki K (2023) Surface - exposed silver nanoclusters inside molecular metal oxide cavities. Nat Chem 15(7):7-37–745. https://doi.org/10.1038/s41557-023-01234-w10.1038/s41557-023-01234-w ↗
46. Yeh YH, Lin YS, Chiu TC, Hu CC (2024) A ratiometric fluorescent sensor for Penicillin G based on color-tunable gold−silver nanoclusters. ACS Omega 9:10621–10627. https://doi.org/10.1021/acsomega.3c0901010.1021/acsomega.3c09010 ↗
47. Justo-Tirado M, Pérez-Herráez I, Escorihuela J, Arenal R, Zaballos-García E, Pérez-Prieto J (2024) Harnessing sustainable nanoclusters for sensitive optical detection of tetracyclines and the underlying mechanism. Nanoscale Adv 6(22):5718–5726. https://doi.org/10.1039/D4NA00637B10.1039/D4NA00637B ↗
48. Tang X, Chi H, Jia Z, Lv J, Lv Y, Wu J (2024) Copper nanoclusters modified molybdenum disulfide quantum dots probe for sensitive detection of tetracycline. Sensing and Bio-Sensing Research 43:100628. https://doi.org/10.1016/j.sbsr.2024.10062810.1016/j.sbsr.2024.100628 ↗
49. Zou T, Li xS, Yao G, Qu R, Yang W, Wang H, Tan W, Yang M (2023) Highly photoluminescent tryptophan-coated copper nanoclusters based turn-off fluorescent probe for determination of tetracyclines. Chemosphere 338:139452. https://doi.org/10.1016/j.chemosphere.2023.13945210.1016/j.chemosphere.2023.139452 ↗
50. Li Y, Huang Y, Sun X, Zhong K, Tang L (2023) An AIE mechanism-based fluorescent probe for relay recognition of HSO3−/H2O2 and its application in food detection and bioimaging. Talanta 258:124412. https://doi.org/10.1016/j.talanta.2023.12441210.1016/j.talanta.2023.124412 ↗
51. Barimah AO, Chao MJ, Tai SM, Sun CD, Agyekum AA, Mao MX, Peng CF, Wang ZP, Addotey TNA (2025) Aggregation induced emission enhancement of nickel nanoclusters for highly sensitive fluorescent “turn on” sensing of chlortetracycline in food. Microchem J 210:112927. https://doi.org/10.1016/j.microc.2025.11292710.1016/j.microc.2025.112927 ↗
52. Qiao M, Fan J, Ding L, Fang Y (2021) Fluorescent ensemble sensors and arrays based on surfactant aggregates encapsulating pyrene-derived fluorophores for differentiation applications. ACS Appl Mater Interfaces 13(16):18395–18412. https://doi.org/10.1021/acsami.1c0375810.1021/acsami.1c03758 ↗
53. Zhang F, Liu M, Liu R, Li J, Sang Y, Tang Y, Wang X, Wang S (2021) A broad-spectrum sensing strategy for the tetracycline family of antibiotics based on an ovalbumin-stabilized gold nanocluster and its application in a pump-free microffuidic sensing platform. Biosens Bioelectron 171:112701. https://doi.org/10.1016/j.bios.2020.11270110.1016/j.bios.2020.112701 ↗
54. Su J, Xiao G, Yang H, Chen J, Li H, Liu X, Luo Y, Li J (2023) Highly sensitive multi-channel biosensor for low-interference simultaneous detection. Nanomaterials 13(2):246. https://doi.org/10.3390/nano1302024610.3390/nano13020246 ↗
55. Nordldeen HAA, Zhang XP, Huang KY, Peng HP, Wu GW, Deng HH, Chen WA (2025) Three-channel sensor array based on PVP/MMI-AuAgNCs for efficient detection of tetracycline antibiotics. Microchem J 209:112744. https://doi.org/10.1016/j.microc.2025.11274410.1016/j.microc.2025.112744 ↗
56. Gong CC, Li ZJ, Liu G, Pu SZ (2021) Ratiometric fluorescent sensing for phosphate based on Eu/Ce/UiO-66-(COOH)2 nanoprobe. Spectrochim Acta A Mol Biomol Spectrosc 252:119493. https://doi.org/10.1016/j.saa.2021.11949310.1016/j.saa.2021.119493 ↗
57. Wu T, Gao X, Ge F, Zheng H (2022) Metal-organic frameworks (MOFs) as fluorescence sensors: principles, development and prospects. Chin Chem Lett 24(45):7881–7901. https://doi.org/10.1039/D2CE01159J10.1039/D2CE01159J ↗
58. Li R, Alomari S, Islamoglu T, Farha OK, Fernando S, Thagard SM, Holsen TM, Wriedt M (2021) Systematic study on the removal of per- and polyfluoroalkyl substances from contaminated groundwater using meta-organic frameworks. Environ Sci Technol 55(22):15162–15171. https://doi.org/10.1021/acs.est.1c0397410.1021/acs.est.1c03974 ↗
59. Zhu T, Chen J, Zeng S, Chen J, Qi C (2023) Highly stable fluorescent-traffic-light sensor for point-of-care detection of tetracycline. ACS Sens 8(11):4272–4280. https://doi.org/10.1021/acssensors.3c0162010.1021/acssensors.3c01620 ↗
60. Wang Q, Du H, Tang R, Wang X, Xie L, Liu J, Sun K, Li Z, Deng G (2024) Boron difluoride modified zinc metal–organic framework-based “off–on” fluorescence sensor for tetracycline and Al3+ detection. Microchim Acta 191(3):144. https://doi.org/10.1007/s00604-024-06211-910.1007/s00604-024-06211-9 ↗
61. Gan ZY, Hu XT, Xu XC, Zhang W, Zou X, Shi J, Zheng K, Arslan M (2021) A portable test strip based on fluorescent europium-based metal–organic framework for rapid and visual detection of tetracycline in food samples. Food Chem 354:129501. https://doi.org/10.1016/j.foodchem.2021.12950110.1016/j.foodchem.2021.129501 ↗
62. Zhang L, He Y, Wu Y, Zhang J, Li S, Zhang Z (2024) Highly sensitive ratiometric fluorescence detection of tetracycline residues in food samples based on Eu/Zr-MOF. Food Chem 436:137717. https://doi.org/10.1016/j.foodchem.2023.13771710.1016/j.foodchem.2023.137717 ↗
63. Li CH, Ji YX, Shi YB, Xu X, Bao LQ, Cui MY, Tian ZH, Zhao ZL (2023) A smart Zn-MOF-based ratiometric fluorescence sensor for accurate distinguish and optosmart sensing of different types of tetracyclines. Appl Surf Sci 640:158442. https://doi.org/10.1016/j.apsusc.2023.15844210.1016/j.apsusc.2023.158442 ↗
64. Wang Y, He L, Wei W, Zhang X, Zeng L, Jiang T, Li J, Chen S, Gao Z (2025) A review of fluorescent covalent organic frameworks for heavy metal ion sensors. Chem Eng J 505:159249. https://doi.org/10.1016/j.cej.2025.15924910.1016/j.cej.2025.159249 ↗
65. Rong MC, Huang Y, Lin CX, Lai LM, Wu YF, Niu L (2024) Recent advances in optical sensing for tetracycline antibiotics. Trac-Trends Anal Chem 178:117839. https://doi.org/10.1016/j.trac.2024.11783910.1016/j.trac.2024.117839 ↗