An in vitro study on macrophage toxicity of allotrope silver nanoparticles
Source abstract
Abstract
Recent studies have established EVQ-218 as a novel type of allotrope silver nanoparticle (AgNP). The patented laser-based method of manufacture imparts EVQ-218 with unique surface properties that enhance particle stability without capping agents and other stabilizing chemistry. In this study, EVQ-218 was screened against RAW 264.7 murine macrophages, MH-S murine alveolar macrophages, and THP-1 human monocyte cell lines. IC50 values were obtained, and cellular uptake and phagocytosis assays were conducted. Results of this study indicate that the intracellular uptake of EVQ-218 did not make any apparent physiologically significant change in cell morphology and phagocytic activity of macrophages at nontoxic doses.
Source: europepmc · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Graphene and Nanomaterials Applications · Nanoparticle-Based Drug Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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