journal article·2024-11

Enhancing nanomedicine with doped carbon quantum dots: a comprehensive review

Hazha Omar Othman, Kovan Dilawer Issa, Diyar Salahuddin Ali, Rebwar Omar Hassan, Esra Tariq Anwer, Sarhang Hayyas Mohammed, Muhammad Ahmad Qadir, Dana Sulaiman Ismail, Diyar Nawzad Omer, Slim Smaoui

Journal of Nanoparticle Research· Volume 26· Issue 11
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Abstract

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OpenAlex topics: Carbon and Quantum Dots Applications · Nanocluster Synthesis and Applications · Graphene and Nanomaterials Applications

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References (89)

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1. Jameel AT, Yaser AZ (2020) Advances In Nanotechnology And Its Applications. Springer10.1007/978-981-15-4742-3 ↗
2. Msto RK, Othman HO, Al-Hashimi BR, Salahuddin Ali D, Hassan DH, Hassan AQ, Smaoui S (2023) Fluorescence Turns On-Off-On Sensing Of Ferric Ion And L-Ascorbic Acid By Carbon Quantum Dots. J Food Qual 2023:555560810.1155/2023/5555608 ↗
3. Silva GA (2004) Introduction To Nanotechnology And Its Applications To Medicine. Surg Neurol 61:216–22010.1016/j.surneu.2003.09.036 ↗
4. Ambesh P, Campia U, Obiagwu C, Bansal R, Shetty V, Hollander G, Shani J (2017) Nanomedicine In Coronary Artery Disease. Indian Heart J 69:244–25110.1016/j.ihj.2017.02.007 ↗
5. Doll TA, Raman S, Dey R, Burkhard P (2013) Nanoscale Assemblies And Their Biomedical Applications. J R Soc Interface 10:2012074010.1098/rsif.2012.0740 ↗
6. Bogunia-Kubik K, Sugisaka M (2002) From Molecular Biology To Nanotechnology And Nanomedicine. Biosystems 65:123–13810.1016/S0303-2647(02)00010-2 ↗
7. Mohanraj V, Chen Y (2006) Nanoparticles-A Review. Trop J Pharm Res 5:561–573
8. Ali DS, Othman HO, Anwer ET (2023) The Advances In Chitosan-Based Drug Delivery Systems For Colorectal Cancer: A Narrative Review. Curr Pharm Biotechnol 24:1554–155910.2174/1389201024666230202160504 ↗
9. Singh I, Arora R, Dhiman H, Pahwa R (2018) Carbon Quantum Dots: Synthesis, Characterization And Biomedical Applications. Turk J Pharm Sci 15:219–23010.4274/tjps.63497 ↗
10. Wu K-J, Edmund C, Shang C, Guo Z (2022) Nucleation And Growth In Solution Synthesis Of Nanostructures-From Fundamentals To Advanced Applications. Prog Mater Sci 123:10082110.1016/j.pmatsci.2021.100821 ↗
11. Molaei MJ (2019) Carbon Quantum Dots And Their Biomedical And Therapeutic Applications: A Review. RSC Adv 9:6460–648110.1039/C8RA08088G ↗
12. Barak Y, Meir I, Shapiro A, Jang Y, Lifshitz E (2018) Fundamental Properties In Colloidal Quantum Dots. Adv Mater 30:180144210.1002/adma.201801442 ↗
13. Tian L, Li Z, Wang P, Zhai X, Wang X, Li T (2021) Carbon Quantum Dots For Advanced Electrocatalysis. J Energy Chem 55:279–29410.1016/j.jechem.2020.06.057 ↗
14. Devi P, Saini S, Kim K-H (2019) The Advanced Role Of Carbon Quantum Dots In Nanomedical Applications. Biosens Bioelectr 141:11115810.1016/j.bios.2019.02.059 ↗
15. Qian Z, Ma J, Shan X, Feng H, Shao L, Chen J (2014) Highly Luminescent N-Doped Carbon Quantum Dots As An Effective Multifunctional Fluorescence Sensing Platform. Chem A Eur J 20:2254–226310.1002/chem.201304374 ↗
16. Wang W, Zeng Z, Zeng G, Zhang C, Xiao R, Zhou C, Xiong W, Yang Y, Lei L, Liu Y (2019) Sulfur Doped Carbon Quantum Dots Loaded Hollow Tubular G-C3n4 As Novel Photocatalyst For Destruction Of Escherichia Coli And Tetracycline Degradation Under Visible Light. Chem Eng J 378:12213210.1016/j.cej.2019.122132 ↗
17. John VL, Nair Y, Vinod T (2021) Doping And Surface Modification Of Carbon Quantum Dots For Enhanced Functionalities And Related Applications. Part Part Syst Charact 38:210017010.1002/ppsc.202100170 ↗
18. Kou X, Jiang S, Park S-J, Meng L-Y (2020) A Review: Recent Advances In Preparations And Applications Of Heteroatom-Doped Carbon Quantum Dots. Dalton Trans 49:6915–693810.1039/D0DT01004A ↗
19. Koutsogiannis P, Thomou E, Stamatis H, Gournis D, Rudolf P (2020) Advances In Fluorescent Carbon Dots For Biomedical Applications. Adv Phys X 5:1758592
20. Pundi A, Chang C-J (2022) Recent Advances In Synthesis, Modification, Characterization And Applications Of Carbon Dots. Polymers 14:215310.3390/polym14112153 ↗
21. Kim K, Kim J (2018) Synthesis Of Carbon Quantum Dots From Jujubes For Detection Of Iron (Iii) Ions. J Nanosci Nanotechnol 18:1320–132210.1166/jnn.2018.14901 ↗
22. Lim SY, Shen W, Gao Z (2015) Carbon Quantum Dots And Their Applications. Chem Soc Rev 44:362–38110.1039/C4CS00269E ↗
23. Ma Z, Ming H, Huang H, Liu Y, Kang Z (2012) One-Step Ultrasonic Synthesis Of Fluorescent N-Doped Carbon Dots From Glucose And Their Visible-Light Sensitive Photocatalytic Ability. New J Chem 36:861–86410.1039/c2nj20942j ↗
24. Cao L, Meziani MJ, Sahu S, Sun Y-P (2013) Photoluminescence Properties Of Graphene Versus Other Carbon Nanomaterials. Acc Chem Res 46:171–18010.1021/ar300128j ↗
25. Xu L, Yuan S, Zeng H, Song J (2019) A Comprehensive Review Of Doping In Perovskite Nanocrystals/Quantum Dots: Evolution Of Structure, Electronics, Optics And Light-Emitting Diodes. Materials Today Nano 6:10003610.1016/j.mtnano.2019.100036 ↗
26. Miao S, Liang K, Zhu J, Yang B, Zhao D, Kong B (2020) Hetero-Atom-Doped Carbon Dots: Doping Strategies. Proper Appl Nano Today 33:10087910.1016/j.nantod.2020.100879 ↗
27. Dimos K (2016) Carbon Quantum Dots: Surface Passivation And Functionalization. Curr Org Chem 20:682–69510.2174/1385272819666150730220948 ↗
28. Kandasamy G (2019) Recent advancements in doped/co-doped carbon quantum dots for multi-potential applications. C, 5(2):24. https://doi.org/10.3390/c502002410.3390/c5020024 ↗
29. Luo W, Wang Y, Lin F, Liu Y, Gu R, Liu W, Xiao C (2020) elenium-doped carbon quantum dots efficiently ameliorate secondary spinal cord injury via scavenging reactive oxygen species. Int J Nan 15:10113–10125. https://doi.org/10.2147/IJN.S28298510.2147/IJN.S282985 ↗
30. Wang Y, Hu A (2014) Carbon Quantum Dots: Synthesis, Properties And Applications. J Mater Chem C 2:6921–693910.1039/C4TC00988F ↗
31. Muthurasu A, Ganesh V (2021) Tuning Optical Properties Of Nitrogen-Doped Carbon Dots Through Fluorescence Resonance Energy Transfer Using Rhodamine B For The Ratiometric Sensing Of Mercury Ions. Anal Methods 13:1857–186510.1039/D1AY00068C ↗
32. Ahmed S, Rehman SU, Tabish M (2022) Cancer Nanomedicine: A Step Towards Improving The Drug Delivery And Enhanced Efficacy Of Chemotherapeutic Drugs. Opennano 7:10005110.1016/j.onano.2022.100051 ↗
33. Wang Y, Li X, Zhao S, Wang B, Song X, Xiao J, Lan M (2022) Synthesis Strategies, Luminescence Mechanisms, And Biomedical Applications Of Near-Infrared Fluorescent Carbon Dots. Coord Chem Rev 470:21470310.1016/j.ccr.2022.214703 ↗
34. Zhao L, Wang X, Jiang M, Wu X, Zhang M, Guan X, Ma J, Zhang W (2021) A Nanosystem Of Copper (Ii)-Disulfiram For Cancer Treatment With High Efficacy And Few Side Effects. Front Mater Sci 15:553–56610.1007/s11706-021-0576-2 ↗
35. Parvin N, Mandal TK (2017) Dually Emissive P, N-Co-Doped Carbon Dots For Fluorescent And Photoacoustic Tissue Imaging In Living Mice. Microchim Acta 184:1117–112510.1007/s00604-017-2108-4 ↗
36. Wei S, Wang Y, Chen W, Li Z, Cheong W-C, Zhang Q, Gong Y, Gu L, Chen C, Wang D (2020) Atomically Dispersed Fe Atoms Anchored On Cof-Derived N-Doped Carbon Nanospheres As Efficient Multi-Functional Catalysts. Chem Sci 11:786–79010.1039/C9SC05005A ↗
37. Wang L, Wang Y, Hu Y, Wang G, Dong S, Hao J (2019) Magnetic Networks Of Carbon Quantum Dots And Ag Particles. J Colloid Inter Sci 539:203–21310.1016/j.jcis.2018.12.037 ↗
38. Wu H, Jiang J, Gu X, Tong C (2017) Nitrogen And Sulfur Co-Doped Carbon Quantum Dots For Highly Selective And Sensitive Fluorescent Detection Of Fe (Iii) Ions And L-Cysteine. Microchim Acta 184:2291–229810.1007/s00604-017-2201-8 ↗
39. Wang L, Zhou HS (2014) Green Synthesis Of Luminescent Nitrogen-Doped Carbon Dots From Milk And Its Imaging Application. Anal Chem 86:8902–890510.1021/ac502646x ↗
40. Zong J, Zhu Y, Yang X, Shen J, Li C (2011) Synthesis Of Photoluminescent Carbogenic Dots Using Mesoporous Silica Spheres As Nanoreactors. Chem Commun 47:764–76610.1039/C0CC03092A ↗
41. Havrdova M, Hola K, Skopalik J, Tomankova K, Petr M, Cepe K, Polakova K, Tucek J, Bourlinos AB, Zboril R (2016) Toxicity Of Carbon Dots-Effect Of Surface Functionalization On The Cell Viability, Reactive Oxygen Species Generation And Cell Cycle. Carbon 99:238–24810.1016/j.carbon.2015.12.027 ↗
42. Rocco D, Moldoveanu VG, Feroci M, Bortolami M, Vetica F (2023) Electrochemical Synthesis Of Carbon Quantum Dots. ChemElectroChem 10:E20220110410.1002/celc.202201104 ↗
43. Shereema RM, Sankar V, Raghu K, Rao TP, Shankar SS (2015) One Step Green Synthesis Of Carbon Quantum Dots And Its Application Towards The Bioelectroanalytical And Biolabeling Studies. Electrochim Acta 182:588–59510.1016/j.electacta.2015.09.145 ↗
44. Liu M, Xu Y, Niu F, Gooding JJ, Liu J (2016) Carbon Quantum Dots Directly Generated From Electrochemical Oxidation Of Graphite Electrodes In Alkaline Alcohols And The Applications For Specific Ferric Ion Detection And Cell Imaging. Analyst 141:2657–266410.1039/C5AN02231B ↗
45. Biswal MR, Bhatia S (2021) Carbon Dot Nanoparticles: Exploring The Potential Use For Gene Delivery In Ophthalmic Diseases. Nanomaterials 11:93510.3390/nano11040935 ↗
46. Pires NR, Santos CM, Sousa RR, Paula R, Cunha PL, Feitosa J (2015) Novel And Fast Microwave-Assisted Synthesis Of Carbon Quantum Dots From Raw Cashew Gum. J Braz Chem Soc 26:1274–1282
47. Sun J, Wang W, Yue Q (2016) Review On Microwave-Matter Interaction Fundamentals And Efficient Microwave-Associated Heating Strategies. Materials 9:23110.3390/ma9040231 ↗
48. Khayal A, Dawane V, Yadav VK, Yadav KK, Khan SH (2021) State of art technology: synthesis of carbon dots and their potential applications in biomedical, research and environmental remediation. Preprints. https://doi.org/10.20944/preprints202108.0522.v110.20944/preprints202108.0522.v1 ↗
49. Bogdal D, Penczek P, Pielichowski J, Prociak A (2003) Microwave assisted synthesis, crosslinking, and processing of polymeric materials. Springer, Berlin Heidelberg, pp. 194–26310.1007/b11051 ↗
50. Prekodravac J, Vasiljević B, Marković Z, Jovanović D, Kleut D, Špitalský Z, Mičušik M, Danko M, Bajuk-Bogdanović D, Todorović–Marković, B. (2019) Green And Facile Microwave Assisted Synthesis Of (Metal-Free) N-Doped Carbon Quantum Dots For Catalytic Applications. Ceram Int 45:17006–1701310.1016/j.ceramint.2019.05.250 ↗
51. Sharma N, Sharma I, Bera MK (2022) Microwave-Assisted Green Synthesis Of Carbon Quantum Dots Derived From Calotropis Gigantea As A Fluorescent Probe For Bioimaging. J Fluoresc 32:1039–104910.1007/s10895-022-02923-4 ↗
52. Schwenke AM, Hoeppener S, Schubert US (2015) Synthesis And Modification Of Carbon Nanomaterials Utilizing Microwave Heating. Adv Mater 27:4113–414110.1002/adma.201500472 ↗
53. Pan M, Xie X, Liu K, Yang J, Hong L, Wang S (2020) Fluorescent Carbon Quantum Dots—Synthesis, Functionalization And Sensing Application In Food Analysis. Nanomaterials 10:93010.3390/nano10050930 ↗
54. Atchudan R, Edison TNJI, Shanmugam M, Perumal S, Somanathan T, Lee YR (2021) Sustainable Synthesis Of Carbon Quantum Dots From Banana Peel Waste Using Hydrothermal Process For In Vivo Bioimaging. Physica E: Low-Dimensional Syst Nanostruc 126:11441710.1016/j.physe.2020.114417 ↗
55. Jiang B, Yang H, Guo Y, Liu C, Song H, Zhou P, Zhang H, Zhou K, Guo Y, Chen H (2022) Developing Electropositive Citric Acid-Polyethylenimine Carbon Quantum Dots With High Biocompatibility And Labeling Performance For Mesenchymal Stem Cells In Vitro And In Vivo. New J Chem 46:2508–251710.1039/D1NJ04990A ↗
56. Dhandapani E, Duraisamy N, Periasamy P (2020) Highly Green Fluorescent Carbon Quantum Dots Synthesis Via Hydrothermal Method From Fish Scale. Mater Today: Proc 26:A1–A5
57. Vibhute A, Patil T, Gambhir R, Tiwari AP (2022) Fluorescent Carbon Quantum Dots: Synthesis Methods, Functionalization And Biomedical Applications. Appl Surf Sci Adv 11:10031110.1016/j.apsadv.2022.100311 ↗
58. Zheng XT, Ananthanarayanan A, Luo KQ, Chen P (2015) Glowing Graphene Quantum Dots And Carbon Dots: Properties, Syntheses, And Biological Applications. Small 11:1620–163610.1002/smll.201402648 ↗
59. Chen P, Peng J, Zhang Z, Wang X, Zhu X, Fan K, Luo P (2022) Solvent-Dependent Carbon Dots For Multifunctional Sensing Of Temperature, Ph, And Proton Pump Inhibitors. Anal Chim Acta 1228:34034110.1016/j.aca.2022.340341 ↗
60. Msto RK, Othman HO, Al-Hashimi BR, Salahuddin Ali D, Hassan DH, Hassan AQ, Smaoui S (2023) Fluorescence Turns On-Off-On Sensing Of Ferric Ion And L-Ascorbic Acid By Carbon Quantum Dots. J Food Qual 2023:1–910.1155/2023/5555608 ↗
61. Das R, Bandyopadhyay R, Pramanik P (2018) Carbon Quantum Dots From Natural Resource: A Review. Mater Today Chem 8:96–10910.1016/j.mtchem.2018.03.003 ↗
62. Tekade RK, Maheshwari R, Soni N, Tekade M, Chougule MB (2017) Nanotechnology For The Development Of Nanomedicine. Elsevier, Nanotechnology-Based Approaches For Targeting And Delivery Of Drugs And Genes10.1016/B978-0-12-809717-5.00001-4 ↗
63. Lee SH, Jun B-H (2019) Silver Nanoparticles: Synthesis And Application For Nanomedicine. Int J Mol Sci 20:86510.3390/ijms20040865 ↗
64. Kumari A, Yadav SK, Yadav SC (2010) Biodegradable Polymeric Nanoparticles Based Drug Delivery Systems. Colloids Surf B: Biointer 75:1–1810.1016/j.colsurfb.2009.09.001 ↗
65. Adabi M, Naghibzadeh M, Adabi M, Zarrinfard MA, Esnaashari SS, Seifalian AM, Faridi-Majidi R, Tanimowo Aiyelabegan H, Ghanbari H (2017) Biocompatibility And Nanostructured Materials: Applications In Nanomedicine. Artif Cells, Nanomed Biotechnol 45:833–84210.1080/21691401.2016.1178134 ↗
66. Sumer B, Gao J (2008) Theranostic Nanomedicine For Cancer. Nanomedicine 3(2):137–140. https://doi.org/10.2217/17435889.3.2.13710.2217/17435889.3.2.137 ↗
67. Foged C (2011) Subunit Vaccines Of The Future: The Need For Safe, Customized And Optimized Particulate Delivery Systems. Ther Deliv 2:1057–107710.4155/tde.11.68 ↗
68. Singh AP, Biswas A, Shukla A, Maiti P (2019) Targeted Therapy In Chronic Diseases Using Nanomaterial-Based Drug Delivery Vehicles. Signal Trans Targeted Ther 4:3310.1038/s41392-019-0068-3 ↗
69. Othman HO, Anwer ET, Ali DS, Hassan RO, Mahmood EE, Ahmed RA, Muhammad RF, Smaoui S, (2024) Recent Advances In Carbon Quantum Dots For Gene Delivery: A Comprehensive Review. J Cellul Physiol 239:e31236. https://doi.org/10.1002/jcp.3123610.1002/jcp.31236 ↗
70. Agarwal V, Bajpai M, Sharma A (2018) Patented And Approval Scenario Of Nanopharmaceuticals With Relevancy To Biomedical Application, Manufacturing Procedure And Safety Aspects. Recent Pat Drug Delivery Formulation 12:40–5210.2174/1872211312666180105114644 ↗
71. Bregoli L, Movia D, Gavigan-Imedio JD, Lysaght J, Reynolds J, Prina-Mello A (2016) Nanomedicine Applied To Translational Oncology: A Future Perspective On Cancer Treatment. Nanomed Nanotechnol Biol Med 12:81–10310.1016/j.nano.2015.08.006 ↗
72. Zingg R, Fischer M (2019) The Consolidation Of Nanomedicine. Wiley Interdiscip Rev Nanomed Nanobiotechnol 11:E156910.1002/wnan.1569 ↗
73. Wu L-P, Wang D, Li Z (2020) Grand Challenges In Nanomedicine. Mater Sci Eng C 106:11030210.1016/j.msec.2019.110302 ↗
74. Wu L, Moghimi SM (2016) A Nanoengineered Peptidic Delivery System With Specificity For Human Brain Capillary Endothelial Cells. Nanomedicine: Nanotechnology. Biol Med 12:474–475
75. Xu Z, Wang D, Cheng Y, Yang M, Wu L-P (2018) Polyester Based Nanovehicles For Sirna Delivery. Mater Sci Eng C 92:1006–101510.1016/j.msec.2018.05.031 ↗
76. Jain RK, Stylianopoulos T (2010) Delivering Nanomedicine To Solid Tumors. Nat Rev Clin Oncol 7:653–66410.1038/nrclinonc.2010.139 ↗
77. Minchinton AI, Tannock IF (2006) Drug Penetration In Solid Tumours. Nat Rev Cancer 6:583–59210.1038/nrc1893 ↗
78. Mohamed EH, Alzahrani YM, Alghamdi HA, Alharthi S, Attia MS, Youssef AO, Ahmed SS, Mahmoud SA (2023) Highly selective optical sensor N/S-doped carbon quantum dots (CQDs) for the assessment of human chorionic gonadotropin β-hCG in the serum of breast and prostate cancer patients. Pharmacy 675. https://buescholar.bue.edu.eg/pharmacy/67510.1039/D3RA01570J ↗
79. Yang Z, Xu M, Liu Y, He F, Gao F, Su Y, Wei H, Zhang Y (2014) Nitrogen-Doped, Carbon-Rich, Highly Photoluminescent Carbon Dots From Ammonium Citrate. Nanoscale 6:1890–189510.1039/C3NR05380F ↗
80. Yang Z, Yao Z, Li G, Fang G, Nie H, Liu Z, Zhou X, Chen XA, Huang S (2012) Sulfur-Doped Graphene As An Efficient Metal-Free Cathode Catalyst For Oxygen Reduction. ACS Nano 6:205–21110.1021/nn203393d ↗
81. Zarghami A, Dolatyari M, Mirtagioglu H, Rostami A (2023) High-Efficiency Upconversion Process In Cobalt And Neodymium Doped Graphene Qds For Biomedical Applications. Sci Rep 13:1027710.1038/s41598-023-37518-x ↗
82. Lu W, Guo Y, Zhang J, Yue Y, Fan L, Li F, Dong C, Shuang S (2022) A High Catalytic Activity Nanozyme Based On Cobalt-Doped Carbon Dots For Biosensor And Anticancer Cell Effect. ACS Appl Mater Interfaces 14:57206–5721410.1021/acsami.2c19495 ↗
83. Demirci S, Mcnally AB, Ayyala RS, Lawson LB, Sahiner N (2020) Synthesis And Characterization Of Nitrogen-Doped Carbon Dots As Fluorescent Nanoprobes With Antimicrobial Properties And Skin Permeability. J Drug Deliv Sci Technol 59:10188910.1016/j.jddst.2020.101889 ↗
84. Shah H, Xie W, Wang Y, Jia X, Nawaz A, Xin Q, Song M, Gong JR (2021) Preparation Of Blue-And Green-Emissive Nitrogen-Doped Graphene Quantum Dots From Graphite And Their Application In Bioimaging. Mater Sci Eng C 119:11164210.1016/j.msec.2020.111642 ↗
85. Wang J, Xu M, Wang D, Li Z, Primo FL, Tedesco AC, Bi H (2019) Copper-Doped Carbon Dots For Optical Bioimaging And Photodynamic Therapy. Inorg Chem 58:13394–1340210.1021/acs.inorgchem.9b02283 ↗
86. Najaflu M, Shahgolzari M, Bani F, Khosroushahi AY (2022) Green Synthesis Of Near-Infrared Copper-Doped Carbon Dots From Alcea For Cancer Photothermal Therapy. ACS Omega 7:34573–3458210.1021/acsomega.2c04484 ↗
87. Xue S, Zhang T, Wang X, Zhang Q, Huang S, Zhang L, Zhang L, Zhu W, Wang Y, Wu M, Zhao Q, Li P, Wu W (2021) Cu, Zn Dopants Boost Electron Transfer Of Carbon Dots For Antioxidation. Small 17:210217810.1002/smll.202102178 ↗
88. Tian B, Liu S, Feng L, Liu S, Gai S, Dai Y, Xie L, Liu B, Yang P, Zhao Y (2021) Renal-Clearable Nickel-Doped Carbon Dots With Boosted Photothermal Conversion Efficiency For Multimodal Imaging-Guided Cancer Therapy In The Second Near-Infrared Biowindow. Adv Func Mater 31:210054910.1002/adfm.202100549 ↗
89. Etefa HF, Nemera DJ, Dejene FB (2023) Green Synthesis Of Nickel Oxide Nps Incorporating Carbon Dots For Antimicrobial Activities. ACS Omega 8:38418–3842510.1021/acsomega.3c05204 ↗