Multifunctional metal ferrite nanoparticles for MR imaging applications
Source abstract
Abstract
Magnetic Resonance Imaging (MRI) is a very powerful non-invasive tool for in vivo imaging and clinical diagnosis. With rapid advancement in nanoscience and nanotechnology, there is rapid growth in nanoparticles-based contrast agents. Progress in synthetic protocols enable synthesis of multifunctional nanoparticles which facilitated efforts toward the development of multimodal contrast agents. In this review, recent developments in metal ferrite-based MR contrast agents have been described. Specifically, effect of size, shape, composition, assembly and surface modification of metal ferrite nanoparticles on their T 2 contrast have been discussed. The review further outlines the effect of leaching on MRI contrast and other various factors which affect the multimodal ability of the (T 1–T 2 and T 2-thermal activation) metal ferrite nanoparticles.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Magnetic Properties and Synthesis of Ferrites · Nanoparticle-Based Drug Delivery · Iron oxide chemistry and applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (57)
Show source-provided references
1. Ai H, Flask C, Weinberg B, Shai X, Pagel MD, Farrell D, Durek J, Gao J (2005) Magnetite loaded polymeric micelles as ultrasensitive magnetic resonance probes. Adv Mater 17:1949–195210.1002/adma.200401904 ↗
2. Amstad E, Gillich T, Bilecka I, Textor M, Reimhult E (2009) Ultrastable iron oxide nanoparticle colloidal suspensions using dispersants with catechol-derived anchor groups. Nano Lett 9:4042–404810.1021/nl902212q ↗
3. Barick KC, Aslam M, Lin YP, Bahadur D, Prasad PV, Dravid VP (2008) Novel and efficient MR active aqueous colloidal Fe3O4 nanoassemblies. J Mater Chem 19:7023–702910.1039/b911626e ↗
4. Caravan P, Ellison JJ, McMurry TJ, Lauffer RB (1999) Gadolinium(III) Chelates as MRI contrast agents: structure, dynamics, and applications. Chem Rev 99:2293–235210.1021/cr980440x ↗
5. Chandra S, Barick KC, Bahadur D (2011) Oxide and hybrid nanostructures for therapeutic applications Adv Drug Del Rev (in press)10.1016/j.addr.2011.06.003 ↗
6. Cheon J, Lee JH (2008) Synergistically integrated nanoparticles as multimodal probes for nanobiotechnology. Acc Chem Res 41:1630–164010.1021/ar800045c ↗
7. Choi JS, Lee JH, Shin TH, Song HT Kim EY, Cheon J (2010) Self-confirming “AND” logic nanoparticles for fault-free MRI. J Am Chem Soc 132:11015–1101710.1021/ja104503g ↗
8. Cole AJ, Yang VC, David AE (2011) Cancer theranostics: the rise of targeted magnetic nanoparticles. Trend Biotechnol 29:323–33210.1016/j.tibtech.2011.03.001 ↗
9. De M, Chou SS, Joshi HM, Dravid VP (2011) Hybrid magnetic nanostructures (MNS) for magnetic resonance imaging applications. Adv Drug Del Rev (in press)10.1016/j.addr.2011.07.001 ↗
10. Dias MHM, Lauterbur DC (1986) Ferromagnetic particles as contrast agents for magnetic resonance imaging of liver and spleen. Mag Res Med 3:32810.1002/mrm.1910030218 ↗
11. Duan H, Kuang M, Wang X, Wang YA, Mao H, Nie S (2008) Reexamining the effects of particle size and surface chemistry on the magnetic properties of iron oxide nanocrystals: new insights into spin disorder and proton relaxivity. J Phys Chem C 112:8127–813110.1021/jp8029083 ↗
12. Erathodiyil N, Ying JY (2011) Functionalization of inorganic nanoparticles for bioimaging applications. Acc Chem Res 44:925–93510.1021/ar2000327 ↗
13. Erb RM, Son HS, Samanta B, Rotello VM, Yellen BB (2009) Magnetic assembly of colloidal super structures with multimodal symmetry. Nature 457:999–100210.1038/nature07766 ↗
14. Fortin JP, Wilhelm C, Servais J, Me’nager C, Bacri JC, Gazeau F (2007) Size-sorted anionic iron oxide nanomagnets as colloidal mediators for magnetic hyperthermia. J Am Chem Soc 129:2628–263510.1021/ja067457e ↗
15. Frey NA, Peng S, Cheng K, Sun S (2009) Magnetic nanoparticles: synthesis and applications in bioimaging and magnetic energy storage. Chem Soc Rev 38:2532–254210.1039/b815548h ↗
16. Gupta AK, Wells S (2004) Surface modified super paramagnetic nanoparticles for drug delivery: preparation characterization and cyto-toxic studies. IEEE Trans Nanobiosci 3:66–7310.1109/TNB.2003.820277 ↗
17. Hayashi K, Moriya M, Sakamoto W, Yogo T (2009) Chemoselective synthesis of folic acid-functionalized magnetite nanoparticles via click chemistry for magnetic hyperthermia. Chem Mater 21:1318–132510.1021/cm803113e ↗
18. Hu X, Norris DG (2004) Advances in high field magnetic resonance imaging. Annu Rev Biomed Eng 6:157–18410.1146/annurev.bioeng.6.040803.140017 ↗
19. Hu F, MacRenaris KW, Water EA, Liang T, Schultz-Sikma EA, Eckermann AL, Meade TJ (2009) Ultrasmall, water-soluble magnetite nanoparticles with high relaxivity for magnetic resonance imaging J Phys Chem C 113:20855–2086010.1021/jp907216g ↗
20. Hu F, MacRenaris KW, Water EA, Schultz-Sikma EA, Eckermann AL, Meade TJ (2010) Highly dispersible, superparamagnetic magnetite nanoflowers for magnetic resonance imaging Chem Commun 46:73–3510.1039/B916562B ↗
21. Hu F, Joshi HM, Dravid VP, Meade T (2010b) High-performance nanostructured MR contrast probes. Nanoscale 2:1884–189110.1039/c0nr00173b ↗
22. Jana N, Earhart C, Ying JY (2007) Synthesis of water-soluble and functionalized nanoparticles by silica coating. Chem Mater 19:5074–508210.1021/cm071368z ↗
23. Jang JT, Nah H, Lee HJ, Moon SH, Kim MG, Cheon J (2009) Critical enhancements of MRI contrast and hyperthermic effects by dopant-controlled magnetic nanoparticles. Angew Chem Int Ed 48:1234–123810.1002/anie.200805149 ↗
24. Jordan A, Scholz R, Wust P, Fahling H, Krause J, Wlodarczyk W, Sander B, Vogl TH, Felix R (1997) Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo. Int J Hyperthermia 13:587–60510.3109/02656739709023559 ↗
25. Joshi HM, Lin YP, Aslam M, Prasad PV, Schultz-Sikma EA, Edelman R, Meade TJ, Dravid VP (2009) Effects of shape and size of cobalt ferrite nanostructures on their MRI contrast and thermal activation. J Phys Chem C 113:11767–17761
26. Jun YW, Huh YM, Choi JS, Lee JH, Song HT, Kim S, Yoon S, Kim KS, Shin JS, Suh JS, Cheon J (2005) Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging. J Am Chem Soc 127:5732–573310.1021/ja0422155 ↗
27. Jun YW, Seo JW, Cheon J (2008a) Nanoscaling laws of magnetic nanoparticles and their applicabilities in biomedical sciences. Acc Chem Res 41:179–18910.1021/ar700121f ↗
28. Jun YW, Lee JH, Cheon J (2008b) Chemical design of nanoparticle probes for high-performance magnetic resonance imaging. Angew Chem Int Ed 47:5122–513510.1002/anie.200701674 ↗
29. Kellar KE, Fujii DK, Gunther WHH, Briley-Saebo K, Spiller KM, Koenig SH (1999) ‘NC100150’, a preparation of iron oxide nanoparticles ideal for positive-contrast MR angiography. Magn Reson Mater Phys, Biol Med 8:207–213
30. Kim J, Kim HS, Lee N, Kim T, Kim H, Yu T, Song IC, Moon WK, Hyeon T (2008) Multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance and fluorescence imaging and for drug delivery. Angew Chem Int Ed 47:8438–844110.1002/anie.200802469 ↗
31. Kim J, Piao Y, Hyeon T (2009) Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy. Chem Soc Rev 38:372–39010.1039/B709883A ↗
32. Koenig SH, Keller KE (1995) Theory of 1/T 1 and 1/T 2 NMRD profiles of solutions of magnetic nanoparticles. Magn Reson Med 34:227–23310.1002/mrm.1910340214 ↗
33. LaConte LEW, Nitin N, Zurkiya O, Caruntu D, O’Connor CJ, Hu X, Bao GJ (2007) Coating thickness of magnetic iron oxide nanoparticles affects R2 relaxivity. Mag Res Imag 26:1634–164110.1002/jmri.21194 ↗
34. Laurent S, Forge D, Port M, Roch A, Robic C, Elst LV, Muller RN (2008) Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 108:2064–211010.1021/cr068445e ↗
35. Lee JH, Huh YM, Jun YW, Seo JW, Jang JT, Song HT, Kim S, Cho EJ, Yoon HG, Suh JS, Cheon J (2007) Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging. Nat Med 13:95–9910.1038/nm1467 ↗
36. Lu AH, Salabas EL, Schuth F (2007) Magnetic nanoparticles: synthesis, protection, functionalization, and application. Angew Chem 46:1222–124410.1002/anie.200602866 ↗
37. Merbach AE, Toth E (2001) The chemistry of contrast agents in medical magnetic resonance Imaging. Wiley, New York
38. Molday RS, Mackenzie D (1982) Immuno-specific ferromagnetic iron-dextran reagents for the labeling and magnetic separation of cells. J Immun Methods 52:353–36710.1016/0022-1759(82)90007-2 ↗
39. Na HB, Hyeon T (2009) Nanostructured T1 MRI contrast agents. J Mater Chem 19:6267–627310.1039/b902685a ↗
40. Na HB, Song IC, Hyeon T (2009) Inorganic nanoparticles for MRI contrast agents. Adv Mater 21:2133–214810.1002/adma.200802366 ↗
41. Park JH, Maltzahn G, Zhang L, Schwartz MP, Ruoslahti E, Bhatia SN, Sailor MJ (2008) Magnetic iron oxide nanoworms for tumor targeting and imaging. Adv Mater 20:1630–163510.1002/adma.200800004 ↗
42. Piao Y,Kim J, Na HB, Kim D, Baek JS, Ko MK, Lee JH, Shokoumehr M, Hyeon T (2008) Wrap–bake–peel process for nanostructural transformation from beta-FeOOH nanorods to biocompatible iron oxide nanocapsules. Nat Mater 7:242–24710.1038/nmat2118 ↗
43. Pinho SLC, Pereira GA, Voisin P, Kassem J, Bouchaud VR, Etienne L, Peters JA, Carlos L, Mornet S, Geraldes CFGC, Rocha J, Delville MH (2010) Fine tuning of the relaxometry of Fe2O3@SiO2 nanoparticles by tweaking the silica coating thickness. ACS Nano 4:5339–534910.1021/nn101129r ↗
44. Prasad NK, Rathinasamy K, Panda D, Bahadur D (2007) Mechanism of cell death induced by magnetic hyperthermia with nanoparticles of Mn x Fe2−x O3 synthesized by a single step process. J Mater Chem 17:5042–505110.1039/b708156a ↗
45. Rosi NL, Mirkin CA (2005) Nanostructures in biodiagnostics. Chem Rev 105:1547–156210.1021/cr030067f ↗
46. Schultz-Sikma EA, Joshi HM, Ma Q, MacRenaris KW, Eckermann AL, Dravid VP, Meade TJ (2011) Probing the chemical stability of mixed ferrites: implications for magnetic resonance contrast agent design. Chem Mater 23:2657–266410.1021/cm200509g ↗
47. Semelka RC, Helmberger TK (2001) Contrast agents for MR imaging of the liver. Radiology 218:27–3810.1148/radiology.218.1.r01ja2427 ↗
48. Seo WS, Less JH, Sun X, Suzuki Y, Mann D, Liu Z, Terashima M, Yang PC, Mcconnell MV, Nishimura DG, Dai H (2006) FeCo/graphitic-shell nanocrystals as advancedmagnetic-resonance-imaging and near-infrared agents. Nature 5:971–97610.1038/nmat1775 ↗
49. Stolnik S, Illum L, Davis SS (1995) Long circulating microparticulate drug carriers. Adv Drug Del Rev 16:195–21410.1016/0169-409X(95)00025-3 ↗
50. Sun C, Lee JSH, Zhang M (2008) Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deli Rev 60:1252–126510.1016/j.addr.2008.03.018 ↗
51. Tassa C, Shaw SY, Weissleder R (2011) Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Acc Chem Res 44:842–85210.1021/ar200084x ↗
52. Tromsdorf UI, Bigall NC, Kaul MG, Bruns OT, Nikolic MS, Mollwitz B, Sperling RA, Reimer R, Hohenberg H, Parak WJ, Forster S, Beiseigel U, Adam G, Weller H (2007) Size and surface effects on the MRI relaxivity of manganese ferrite nanoparticle contrast agents. Nano Lett 7:2422–242710.1021/nl071099b ↗
53. Veiseh O, Gunn JW, Zhang M (2010) Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. Adv Drug Deliv Rev 62:284–30410.1016/j.addr.2009.11.002 ↗
54. Wan J, Cai W, Meng X, Liu E (2007) Monodisperse water-soluble magnetite nanoparticles prepared by polyol process for high-performance magnetic resonance imaging. Chem Commun 5004–400610.1039/b712795b ↗
55. Weissleder R, Bogdanov A, Neuwelt EA, Papisov M (1995) Long-circulating iron oxides for MR imaging. Adv Drug Del Rev 16:321–33410.1016/0169-409X(95)00033-4 ↗
56. Xie J, Xu C, Kohler N, Hou Y, Sun S (2007) Controlled PEGylation of monodisperse Fe3O4 nanoparticles for reduced non-specific uptake by macrophage cells. Adv Mater 19:3163–316610.1002/adma.200701975 ↗
57. Yellen BB, Erb RM (2008) Manipulation and detection of magnetic nanoparticles for diagnostic applications book title: handbook of biosensors and biochips. doi 10.1002/9780470061565.hbb138