journal article·2009-02

Gelatin–Chitosan composite capped gold nanoparticles: a matrix for the growth of hydroxyapatite

S. S. Liji Sobhana, J. Sundaraseelan, S. Sekar, T. P. Sastry, A. B. Mandal

Journal of Nanoparticle Research· Volume 11· Issue 2
Publisher page

Abstract

Growth of hydroxyapatite (HA) on gelatin–chitosan composite capped gold nanoparticles is presented for the first time by employing wet precipitation methods and we obtained good yields of HA. Fourier transform infrared spectroscopy (FTIR) spectrum has shown the characteristic bands of phosphate groups in the HA. Scanning electron microscopy (SEM) pictures have shown spherical nanoparticles with the size in the range of 70–250 nm, whereas ≥2–50 nm sized particles were visualized in high resolution transmission electron microscopy (HR-TEM). X-ray diffraction (XRD) spectrum has shown Bragg reflections which are comparable with the HA. Energy dispersive X-ray (EDX) studies have confirmed calcium/phosphate stoichiometric ratio of HA. The thermogravimetric analysis (TGA) has shown about 74% of inorganic crystals in the nanocomposite formed. These results have revealed that gelatin–chitosan capped gold nanoparticles, acted as a matrix for the growth of HA.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Pigment Synthesis and Properties · Collagen: Extraction and Characterization

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References (31)

Show source-provided references
1. Aryal S, Bahadur R, Bhattarai SR, Prabu P, Kim HY (2006) Immobilization of collagen on gold nanoparticles: preparation, characterization, and hydroxyapatite growth. J Mater Chem 16:4642–464810.1039/b608300e ↗
2. Borginon H (1967) Photographic properties of the gelatin macromolecule. J Photogr Sci 15:207–21410.1080/00223638.1967.11737408 ↗
3. Chang MC, Ikoma T, Kikuchi M, Tanaka J (2001) Preparation of a porous hydroxyapatite/collagen nanocomposite using glutaraldehyde as a crosslinkage agent. J Mater Sci Lett 20:1199–120110.1023/A:1010914621089 ↗
4. David L, Argenta L, Fisher D (2005) Hydroxyapatite cement in pediatric craniofacial reconstruction. J Craniofac Surg 16:129–13310.1097/00001665-200501000-00026 ↗
5. Du C, Cui FZ, Zhu XD, de Groot K (1999) Three-dimensional nano-HAp/collagen matrix loading with osteogenic cells in organ culture. J Biomed Mater Res 44:407–41510.1002/(SICI)1097-4636(19990315)44:4<407::AID-JBM6>3.0.CO;2-T ↗
6. Dufresne A, Cavaille JY, Dupeyre D, Garcia-Ramirez M, Romero J (1999) Morphology, phase continuity and mechanical behaviour of polyamide 6 chitosan blends. Polymer 40:1657–166610.1016/S0032-3861(98)00335-8 ↗
7. Elcin AE, Elcin YM, Pappas GD (1998) Neural tissue engineering: adrenal chromaffin cell attachment and viability on chitosan scaffolds. Neurol Res 20:648–65410.1080/01616412.1998.11740578 ↗
8. Esumi K, Takei N, Yoshimura T (2003) Antioxidant-potentiality of gold–chitosan nanocomposites. Colloids Surf B Biointerfaces 32:117–12310.1016/S0927-7765(03)00151-6 ↗
9. Geiger M, Li RH, Friess W (2003) Collagen sponges for bone regeneration with rhBMP-2. Adv Drug Deliv Rev 55:1613–162910.1016/j.addr.2003.08.010 ↗
10. Gineste L, Gineste M, Ranz X, Ellefterion A, Guilhem A, Rouquet N, Frayssinet P (1999) Degradation of hydroxylapatite, fluorapatite, and fluorhydroxyapatite coatings of dental implants in dogs. J Biomed Mater Res 48:224–23410.1002/(SICI)1097-4636(1999)48:3<224::AID-JBM5>3.0.CO;2-A ↗
11. Huang J, Best SM, Bonfield W, Brooks RA, Rushton N, Jayasinghe SN, Edirisinghe MJ (2004) In vitro assessment of the biological response to nano-sized hydroxyapatite. J Mater Sci Mater Med 15:441–44510.1023/B:JMSM.0000021117.67205.cf ↗
12. Khor E, Lim LY (2003) Implantable applications of chitin and chitosan. Biomaterials 24:2339–234910.1016/S0142-9612(03)00026-7 ↗
13. Kometani N, Tsubonishi M, Fujita T, Asami K, Yonezawa Y (2001) Preparation and optical absorption spectra of dye-coated Au, Ag, and Au/Ag colloidal nanoparticles in aqueous solutions and in alternate assemblies. Langmuir 17:578–58010.1021/la0013190 ↗
14. Liu Q, de Wijn JR, van Blitterswijk CA (1998) A study on the grafting reaction of isocyanates with hydroxyapatite particles. J Biomed Mater Res 40:358–36410.1002/(SICI)1097-4636(19980605)40:3<358::AID-JBM3>3.0.CO;2-E ↗
15. Ma PX, Langer R (1995) In: Mikos AG et al (eds) Polymers in medicine and pharmacy. MRS, Pittsburgh, pp 99–104
16. Manna A, Chen PL, Akiyama H, Wei TX, Tamada K, Knoll W (2003) Optimized photoisomerization on gold nanoparticles capped by unsymmetrical azobenzene disulfides. Chem Mater 15:20–2810.1021/cm0207696 ↗
17. Mao JS, Zhao LG, Yin YJ, Yao KD (2003) Structure and properties of bilayer chitosan–gelatin scaffolds. Biomaterials 24:1067–107410.1016/S0142-9612(02)00442-8 ↗
18. Mikos AG, Thorsen AJ, Czerwonka LA, Bao Y, Langer R, Winslow DN, Vacanti JP (1994) Preparation and characterization of poly(L-lactic acid) foams. Polymer 35:1068–107710.1016/0032-3861(94)90953-9 ↗
19. Misra TK, Chen TS, Liu CY (2006) Phase transfer of gold nanoparticles from aqueous to organic solution containing resorcinarene. J Colloid Interface Sci 297:584–58810.1016/j.jcis.2005.11.013 ↗
20. Mochizuki A, Sato Y, Ogawara H, Yamashita S (1989) Pervaporation separation of water/ethanol mixtures through polysaccharide membranes. II. The permselectivity of chitosan membrane. J Appl Polym Sci 37(12):3375−338410.1002/app.1989.070371209 ↗
21. Murphy CJ, San TK, Gole AM, Orendorff CJ, Gao JX, Gou L, Hunyadi SE, Li T (2005) Anisotropic metal nanoparticles: synthesis, assembly, and optical applications. J Phys Chem B 109:13857–1387010.1021/jp0516846 ↗
22. Park YM, Ryu SC, Yoon SY, Stevens R, Park HC (2008) Preparation of whisker-shaped hydroxyapatite/β-tricalcium phosphate composite. Mater Chem Phys, doi: 10.1016/j.matchemphys.2007.12.01310.1016/j.matchemphys.2007.12.013 ↗
23. Rezania A., Healy KE (1999) Biomimetic peptide surfaces that regulate adhesion, spreading, cytoskeletal organization, and mineralization of the matrix deposited by osteoblast-like cells. Biotechnol Prog 15:19–3210.1021/bp980083b ↗
24. Rose F., Oreffo ROC, Nf (2002) Bone tissue engineering: hope vs hype. Biochem Biophys Res Commun 292:1–710.1006/bbrc.2002.6519 ↗
25. Shea LD, Wang D, Franceschi RT, Mooney DJ (2000) Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds. Tissue Eng 6:605–61710.1089/10763270050199550 ↗
26. Su CH, Wu PL, Yeh CS (2003) Sonochemical synthesis of well-dispersed gold nanoparticles at the ice temperature. J Phys Chem B 107:14240–1424310.1021/jp035451v ↗
27. Suh JKF, Matthew HWT (2000) Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review. Biomaterials 21:2589–259810.1016/S0142-9612(00)00126-5 ↗
28. Sun YG, Xia YN (2002) Shape-controlled synthesis of gold and silver nanoparticles. Science 298:2176–217910.1126/science.1077229 ↗
29. Yao CH, Sun JS, Lin FH, Liao CJ, Huang CW (1996) Biological effects and cytotoxicity of tricalcium phosphate and formaldehyde cross-linked gelatin composite. Mater Chem Phys 45:6–1410.1016/0254-0584(96)80040-X ↗
30. Zhao F, Grayson WL, Ma T, Bunnell B, Lu WW (2006) Effects of hydroxyapatite in 3-D chitosan–gelatin polymer network on human mesenchymal stem cell construct development. Biomaterials 27:1859–186710.1016/j.biomaterials.2005.09.031 ↗
31. Zhao F, Yin YJ, Lu WW, Leong JC, Zhang WJ, Zhang JY, Zhang MF, Yao KD (2002) Preparation and histological evaluation of biomimetic three-dimensional hydroxyapatite/chitosan–gelatin network composite scaffolds. Biomaterials 23:3227–323410.1016/S0142-9612(02)00077-7 ↗