journal article·2010-08

Investigation of Mg(OH)2 nanoparticles as an antibacterial agent

Chunxu Dong, John Cairney, Qunhui Sun, Orville Lee Maddan, Gaohong He, Yulin Deng

Journal of Nanoparticle Research· Volume 12· Issue 6
Publisher page

Abstract

Our experimental results of using Mg(OH)2 nanoparticles as an antibacterial agent are reported in this study. The antibacterial behavior of Mg(OH)2 nanoparticles in liquid culture and in paper sheets was investigated. The colony forming units (CFU) counting and the headspace gas chromatography (HS-GC) measurement were used to determine the cell viability. Results indicate that Mg(OH)2 nanoparticles are effective antibacterial agent against Escherichia coli (E. coli) and Burkholderia phytofirmans, and the OH− and Mg2+ ions in Mg(OH)2 water suspension were found not to be the reason for killing the bacteria. Mg(OH)2 nanoparticles could be added directly to wood pulp to make paper sheets, whose antibacterial efficiency increased with the increase of the nanoparticle amount. The possible mechanism of antibacterial effect of Mg(OH)2 nanoparticles is discussed.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Magnesium Oxide Properties and Applications · Nanoparticles: synthesis and applications · Nanocomposite Films for Food Packaging

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (17)

Show source-provided references
1. Chai X, Dong C, Deng Y (2008) In situ determination of bacterial growth by multiple headspace extraction gas chromatography. J Anal Chem 80(20):7820. doi: 10.1021/ac801537x10.1021/ac801537x ↗
2. Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF (2006) Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests. Int J Antimicrob Agents 27:513–517. doi: 10.1016/j.ijantimicag.2006.01.00810.1016/j.ijantimicag.2006.01.008 ↗
3. Feng QL, Wu J, Chen GQ, Cui FZ, Kim TN, Kim JO (2000) A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res A 52(4):662–668. doi: 10.1002/1097-4636(20001215)52:4<662:AID-JBM10>3.0.CO;2-310.1002/1097-4636(20001215)52:4<662::AID-JBM10>3.0.CO;2-3 ↗
4. Giorgi R, Bozzi C, Dei L, Gabbiani C, Ninham BW, Baglioni P (2005) Nanoparticles of Mg(OH)2: synthesis and application to paper conservation. Langmuir 21:8495–8501. doi: 10.1021/la050564m10.1021/la050564m ↗
5. Jeon HJ, Yi SC, Oh SG (2003) Preparation and antibacterial effects of Ag-SiO2 thin films by sol–gel method. Biomaterials 24:4921–4928. doi: 10.1016/S0142-9612(03)00415-010.1016/S0142-9612(03)00415-0 ↗
6. Jiao CM, Wang ZZ, Ye Z, Hu Y, Fan WC (2006) Flame retardation of ethylene–vinyl acetate copolymer using nano magnesium hydroxide and nano hydrotalcite. J Fire Sci 24:47–64. doi: 10.1177/073490410605316010.1177/0734904106053160 ↗
7. Jung WK, Koo HC, Kim KW, Sook S, Kim SH, Park YH (2008) Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol 74:2171–2178. doi: 10.1128/AEM.02001-0710.1128/AEM.02001-07 ↗
8. Liu XF, Yang DZ, Guan YL, Li Z, Yao KD (2001) Antibacterial action of chitosan and carboxymethylated chitosan. J Appl Polymer Sci 79:1324–1335. doi: 10.1002/1097-4628(20010214)79:7<1324:AID-APP210>3.0.CO;2-L10.1002/1097-4628(20010214)79:7<1324::AID-APP210>3.0.CO;2-L ↗
9. Maddan OL (2008) Nanoparticle metal hydroxides and methods of preparing same, US Patent application number: 11/836,746, Publication number: US 2008/0054221 A1
10. Mendonca AF, Amoroso TL, Knabel SJ (1994) Destruction of gram-negative food-borne pathogens by high pH Involves disruption of the cytoplasmic membrane. Appl Environ Microbiol 60(11):4009–401410.1128/AEM.60.11.4009-4014.1994 ↗
11. Sawai J, Kojima H, Igarashi H, Hashimoto A, Shoji S, Sawai K, Hakoda A, Kawada E, Kokugan T, Shimizu M (2000) Antibacterial characteristics of magnesium oxide powder. World J Microbiol Biotechnol 16:187–194. doi: 10.1023/A:100891620978410.1023/A:1008916209784 ↗
12. Stoimenov PK, Klinger RL, Marchin GL, Klabunde KJ (2002) Metal oxide nanoparticles as bactericidal agents. Langmuir 18:6679–6686. doi: 10.1021/la020237410.1021/la0202374 ↗
13. Sudarshan NR, Hoover DG, Knorr D (1992) Antibacterial action of chitosan. Food Biotechnol 6:257–27210.1080/08905439209549838 ↗
14. Wang XJ, Qiao XL, Chen JG, Wang HS, Ding SY (2003) Advancement in research on inorganic antibacterial material. J Ceram (in Chinese) 24:39–44
15. Yoshinari M, Oda Y, Kato T, Okuda K (2001) Influence of surface modifications to titanium on antibacterial activity in vitro. Biomaterials 22:2043–2048. doi: 10.1016/S0142-9612(00)00392-610.1016/S0142-9612(00)00392-6 ↗
16. Yu JC, Ho WK, Lin J, Yip H, Wong PK (2003) Photocatalytic activity, antibacterial effect, and photoinduced hydrophilicity of TiO2 films coated on a stainless steel substrate. Environ Sci Technol 37:2296–2301. doi: 10.1016/j.jphotochem.2008.12.02110.1021/es0259483 ↗
17. Zhang LL, Jiang YH, Ding YL, Povey M, York D (2007) Investigation into the antibacterial behavior of suspensions of ZnO nanoparticles (ZnO nanofluids). J Nanoparticle Res 9:479–489. doi: 10.1007/s11051-006-9150-110.1007/s11051-006-9150-1 ↗