Antibacterial activity of MgO nanoparticles based on lipid peroxidation by oxygen vacancy
Source abstract
Abstract
Antibacterial activity of MgO nanoparticles (NPs) was evaluated against the Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa as well as the Gram-positive bacterium Staphylococcus aureus by microtitre plate-based assay incorporating resazurin as an indicator of cell growth. MgO NPs exhibited antibacterial activity with minimal inhibitory concentration of 500 μg/mL against E. coli and 1,000 μg/mL for P. aeruginosa and S. aureus. MgO NPs enhanced ultrasound-induced lipid peroxidation in the liposomal membrane. It was suggested that the mechanism of the antibacterial activity of the MgO NPs relied on the presence of defects or oxygen vacancy at the surface of the nanoparticle which led to the lipid peroxidation and reactive oxygen species generation.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Nanoplatforms for cancer theranostics · Bone Tissue Engineering Materials
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References (47)
Show source-provided references
1. Alavi MA, Morsali A (2010) Synthesis and characterization of Mg(OH)2 and MgO nanostructures by ultrasonic method. Ultrason Sonochem 17:441–44610.1016/j.ultsonch.2009.08.013 ↗
2. Berger T, Sterrer M, Stankic S, Bernardi J, Diwald O, Knozinger E (2005) Trapping of photogenerated charges in oxide nanoparticles. Mater Sci Eng C 25:664–66810.1016/j.msec.2005.06.013 ↗
3. Bertinetti L, Drouet C, Combes C, Rey C, Tampieri A, Coluccia S, Martra G (2009) Surface characteristics of nanocrystalline apatites: effect of Mg surface enrichment on morphology, surface hydration species, and cationic environments. Langmuir 25:5647–565410.1021/la804230j ↗
4. Boubeta CM, Balcells L, Cristòfol R, Sanfeliu C, Rodríguez E, Weissleder R, Piedrafita S, Simeonidis K, Angelakeris M et al (2010) Self-assembled multifunctional Fe/MgO nanospheres for magnetic resonance imaging and hyperthermia. Nanomedicine 6:362–37010.1016/j.nano.2009.09.003 ↗
5. Chatterjee SN, Agarwal S (1988) Liposomes as membrane model for study of lipid peroxidation. Free Radic Biol Med 4:51–7210.1016/0891-5849(88)90011-1 ↗
6. Di DR, He ZZ, Sun ZQ, Liu J (2012) A new nano-cryosurgical modality for tumor treatment using biodegradable MgO nanoparticles. Nanomedicine. doi: 10.1016/j.nano.2012.02.010 (in press)10.1016/j.nano.2012.02.010 ↗
7. Fang M, Chen JH, Xu XL, Yang PH, Hildebrand HF (2006) Antibacterial activities of inorganic agents on six bacteria associated with oral infections by two susceptibility tests. Int J Antimicrob Agents 27:513–51710.1016/j.ijantimicag.2006.01.008 ↗
8. Fang C, Bhattarai N, Sun C, Zhang M (2009) Functionalized nanoparticles with long-term stability in biological media. Small 5:1637–164110.1002/smll.200801647 ↗
9. Feng B, Hong RY, Wang LS, Guo L, Li HZ, Ding J, Zheng Y, Wei G (2008) Synthesis of Fe3O4/APTES/PEG diacid functionalized magnetic nanoparticles for MR imaging. Colloids Surf A 328:52–5910.1016/j.colsurfa.2008.06.024 ↗
10. French GL (2005) Clinical impact and relevance of antibiotic resistance. Adv Drug Deliv Rev 57:1514–152710.1016/j.addr.2005.04.005 ↗
11. Gu F, Wang SF, Lu MK, Zou WG, Zhou GJ, Xu D, Yuan DR (2004) Combustion synthesis and luminescence properties of Dy3+-doped MgO nanocrystals. J Cryst Growth 260:507–51010.1016/j.jcrysgro.2003.08.044 ↗
12. Hu W, Peng C, Luo W, Lv M, Li X, Li D, Huang Q, Fan C (2010) Graphene based antibacterial paper. ACS Nano 4:4317–432310.1021/nn101097v ↗
13. Jana AK, Agarwal S, Chatterjee SN (1990) The induction of lipid peroxidation in liposomal membrane by ultrasound and the role of hydroxyl radicals. Radiat Res 124:7–1410.2307/3577687 ↗
14. Jung WK, Koo HC, Kim KW, Shin S, Kim SH, Park YH (2008) Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl Environ Microbiol 74:2171–217810.1128/AEM.02001-07 ↗
15. Kanagalakshmi K, Premanathan M, Priyanka R, Hemalatha B, Vanangamudi A (2010) Synthesis, anticancer and antioxidant activities of isoflavanone and 2,3-diarylchromanones. Eur J Med Chem 45:2447–245210.1016/j.ejmech.2010.02.028 ↗
16. Karthikeyan K, Poornaprakash N, Selvakumar N, Jeyasubrmanian K (2009) Thermal properties and morphology of MgO–PVA nanocomposite film. J Nanostruct Polym Nanocompos 5:83–88
17. Kim JS, Kuk E, Yu KN, Kim JH, Park SJ, Lee HJ, Kim SH, Park YK, Park YH, Hwang CY et al (2007) Antimicrobial effects of silver nanoparticles. Nanomedicine 3:95–10110.1016/j.nano.2006.12.001 ↗
18. Krishnamoorthy K, Mohan R, Kim S-J (2011) Graphene oxide as a photocatalytic material. Appl Phys Lett 98:3–24410110.1063/1.3599453 ↗
19. Kumar A, Vemula PK, Ajayan PM, John G (2008) Silver-nanoparticle-embedded antimicrobial paints based on vegetable oil. Nat Mater 7:236–24110.1038/nmat2099 ↗
20. Kumar N, Sanyal D, Sundaresan A (2009) Defect induced ferromagnetism in MgO nanoparticles studied by optical and positron annihilation spectroscopy. Chem Phys Lett 477:360–36410.1016/j.cplett.2009.07.037 ↗
21. Kumari L, Li WZ, Vannoy CH, Leblanc RM, Wang DZ (2009) Synthesis, characterization and optical properties of Mg(OH)2 micro-/nanostructure and its conversion to MgO. Ceram Int 35:3355–336410.1016/j.ceramint.2009.05.035 ↗
22. Li Y, Leung P, Yao L, Song QW, Newton E (2006) Antimicrobial effect of surgical masks coated with nanoparticles. J Hosp Infect 62:58–6310.1016/j.jhin.2005.04.015 ↗
23. Liu XF, Yang DZ, Guan YL, Li Z, Yao KD (2001) Antibacterial action of chitosan and carboxymethylated chitosan. J Appl Polym Sci 79:1324–133510.1002/1097-4628(20010214)79:7<1324::AID-APP210>3.0.CO;2-L ↗
24. Long TC, Saleh N, Tilton RD, Lowry GV, Veronesi B (2006) Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. Environ Sci Technol 40:4346–435210.1021/es060589n ↗
25. Lovric J, Cho SJ, Winnik FM, Maysinger D (2005) Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death. Chem Biol 12:1227–123410.1016/j.chembiol.2005.09.008 ↗
26. Makhluf S, Dror R, Nitzan Y, Abramovich Y, Jelinek R, Gedanken A (2005) Microwave-assisted synthesis of nanocrystalline MgO and its use as a bacteriocide. Adv Funct Mater 15:1708–171510.1002/adfm.200500029 ↗
27. Mureinik R, Guy R (2003) Magnesium as a dietary supplement. Innovations in Food Technology August 16–17
28. Okouchi S, Murata R, Sugita H, Moriyoshi Y, Maeda N (1998) Calorimetric evaluation of the antimicrobial activities of calcined dolomite. J Antibact Antifung Agents 26:109–114
29. Premanathan M, Karthikeyan K, Jeyasubramanian K, Manivannan G (2011) Selective toxicity of ZnO nanoparticles toward Gram-positive bacteria and cancer cells by apoptosis through lipid peroxidation. Nanomedicine 7:184–19210.1016/j.nano.2010.10.001 ↗
30. Pryor WA (1977) The involvement of free radicals in aging and carcinogenesis. In: Mathieu VJ (ed) Medicinal chemistry. Elsevier, Amsterdam, pp 59–331
31. Pryor WA (1980) Methods of detecting free radicals and free radical mediated pathology in environment toxicology. In: Bhatnager RS (ed) Molecular basis of environmental toxicity. Ann Arbor Publishers Inc, Ann Arbor, pp 3–36
32. Raghupathi KR, Koodali RT, Manna AC (2011) Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles. Langmuir 27:4020–402810.1021/la104825u ↗
33. Rezaei M, Khajenoori M, Nematollahi B (2011) Synthesis of high surface area nanocrystalline MgO by pluronic P123 triblock copolymer surfactant. Powder Technol 205:112–11610.1016/j.powtec.2010.09.001 ↗
34. Roselli M, Finamore A, Garaguso I, Britti MS, Mengheri E (2003) Zinc oxide protects cultured enterocytes from the damage induced by Escherichia coli. J Nutr 133:4077–408210.1093/jn/133.12.4077 ↗
35. Sarker SD, Nahar L, Kumarasamy Y (2007) Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals. Methods 42:321–32410.1016/j.ymeth.2007.01.006 ↗
36. Sawai J, Kojima H, Igarashi H, Hashimoto A, Shoji S, Sawaki T, Hakoda A, Kawada E, Kokugan T, Shimizu M (2000) Antibacterial characteristics of magnesium oxide powder. World J Microbiol Biotechnol 16:187–19410.1023/A:1008916209784 ↗
37. Stankic S, Müller M, Diwald O, Sterrer M, Knözinger E, Bernardi J (2005) Size-dependent optical properties of MgO nanocubes. Angew Chem Int Ed 44:4917–492010.1002/anie.200500663 ↗
38. Sterrer M, Diwald O, Knozinger E (2000) Vacancies and electron deficient surface anions on the surface of MgO nanoparticles. J Phys Chem B 104:3601–360710.1021/jp993924l ↗
39. Sterrer M, Berger T, Diwald O, Knozinger E (2003) Energy transfer on the MgO surface monitored by UV induced H2 chemisorption. J Am Chem Soc 125:195–19910.1021/ja028059o ↗
40. Stoimenov PK, Klinger RL, Marchin GL, Klabunde KJ (2002) Metal oxide nanoparticles as bactericidal agents. Langmuir 18:6679–668610.1021/la0202374 ↗
41. Sudarshan NR, Hoover DG, Knorr D (1992) Antibacterial action of chitosan. Food Biotechnol 6:257–27210.1080/08905439209549838 ↗
42. Ugur SS, Sarnsik M, Aktas AH, Ucar MC, Erden E (2010) Modifying of cotton fabric surface with nano-ZnO multilayer films by layer-by-layer deposition method. Nanoscale Res Lett 5:1204–121010.1007/s11671-010-9627-9 ↗
43. Veerapandian M, Yun KS (2011) Functionalization of biomolecules on nanoparticles: specialized for antibacterial applications. Appl Microbiol Biotechnol 90:1655–166710.1007/s00253-011-3291-6 ↗
44. Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE (2006) Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 6:1794–180710.1021/nl061025k ↗
45. Yamamoto O (2001) Influence of particle size on the antibacterial activity of zinc oxide. Int J Inorg Mater 3:643–64610.1016/S1466-6049(01)00197-0 ↗
46. Zhang LL, Jiang YH, Ding YL, Povey M, York D (2007) Investigation into the antibacterial behavior of suspensions of ZnO nanoparticles (ZnO nanofluids). J Nanopart Res 9:479–48910.1007/s11051-006-9150-1 ↗
47. Zhang Q, Joo JB, Lu Z, Dahl M, Oliveira DQL, Ye M, Yin Y (2011) Self-assembly and photocatalysis of mesoporous TiO2 nanocrystal clusters. Nano Res 4:103–11410.1007/s12274-010-0058-9 ↗