Acute toxicities of six manufactured nanomaterial suspensions to Daphnia magna
Source abstract
Abstract
The rapid growth of nanotechnology is stimulating research on the potential environmental impacts of manufactured nanomaterials (MNMs). This paper summarizes a comprehensive study on the 48-h acute toxicity of water suspensions of six MNMs (i.e., ZnO, TiO2, Al2O3, C60, SWCNTs, and MWCNTs) to Daphnia magna, using immobilization and mortality as toxicological endpoints. The results show that the acute toxicities of all MNMs tested are dose dependent. The EC50 values for immobilization ranged from 0.622 mg/L (ZnO NPs) to 114.357 mg/L (Al2O3 NPs), while the LC50 values for mortality ranged from 1.511 mg/L (ZnO NPs) to 162.392 mg/L (Al2O3 NPs). In these tests, TiO2, Al2O3, and carbon-based nanomaterials were more toxic than their bulk counterparts. Moreover, D. magna were found to ingest nanomaterials from the test solutions through feeding behaviors, which indicates that the potential ecotoxicities and environmental health effects of these MNMs cannot be neglected.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticles: synthesis and applications · Heavy metals in environment · Heavy Metal Exposure and Toxicity
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (29)
Show source-provided references
1. Adams LK, Lyon DY, McIntosh A, Alvarez PJJ (2006) Comparative eco-toxicity of nano-scale TiO2, SiO2 and ZnO water suspensions. Water Res 40(19):3527–353210.1016/j.watres.2006.08.004 ↗
2. Alberdi JL, Sáenz ME, Di Marzio WD, Tortorelli MC (1996) Comparative acute toxicity of two herbicides, Paraquat and Glyphosate, to D. magna and D. spinulata. Bull Environ Contam Toxicol 57:229–23510.1007/s001289900180 ↗
3. Colvin VL (2003) The potential environmental impact of engineered nanomaterials. Nat Biotechnol 21:1166–117010.1038/nbt875 ↗
4. Ebert D (2005) Ecology, epidemiology, and evolution of parasitism in Daphnia. National Library of Medicine (US), National Center for Biotechnology Information, Bethesda, MD. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Books . Accessed 19 Mar 2008
5. EPA probit analysis program used for calculating LC/EC values (1992) version 1.5. http://www.epa.gov/nerleerd/stat2/probit.zip . Accessed 09 May 2007
6. EPA 100/B-07/001 (2007) U.S. Environmental Protection Agency Final Nanotechnology White Paper. Science Policy Council, U.S. Environmental Protection Agency, Washington, DC 20460, 15 February 2007. http://www.epa.gov/osa/pdfs/nanotech/epa-nanotechnology-white-paper-final-february-2007.pdf . Accessed 09 Mar 2007.
7. Hund-Rinke K, Simon M (2006) Ecotoxic effect of photocatalytic active nanoparticles (TiO2) on algae and daphnids. Environ Sci Pollut Res 13(4):225–23210.1065/espr2006.06.311 ↗
8. Jeng HA, Swanson J (2006) Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health A 41:2699–271110.1080/10934520600966177 ↗
9. Lovern SB, Klaper R (2006) Daphnia magna mortality when exposed to titanium dioxide and fullerene (C60) nanoparticles. Environ Toxicol Chem 25(4):1132–113710.1897/05-278R.1 ↗
10. Lyon D, Fortner J, Sayes C, Colvin V, Hughes J (2005) Bacterial cell association and antimicrobial activity of a C60 water suspension. Environ Toxicol Chem 24:2757–276210.1897/04-649R.1 ↗
11. Lyon D, Adams L, Joshua C, Falkner J, Alvarez PJJ (2006) Antibacterial activity of fullerene water suspensions: effects of preparation method and particle size. Environ Sci Technol 40:4360–436610.1021/es0603655 ↗
12. Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311:622–62710.1126/science.1114397 ↗
13. Oberdörster E, Zhu S, Blickley TM, McClellan-Green P, Haasch ML (2006) Ecotoxicology of carbon-based engineered nanoparticles: effects of fullerene (C60) on aquatic organisms. Carbon 44:1112–112010.1016/j.carbon.2005.11.008 ↗
14. OECD (2000) Draft guidance document on aquatic toxicity testing of difficult substances and mixtures. Environmental Health and Safety Publications. Series on Testing and Assessment, no. 23
15. OECD 202 (2004) OECD guideline for the testing of chemicals. ‘Daphnia sp., acute immobilisation test’
16. Panessa-Warren BJ, Warren JB, Wong SS, Misewich JA (2006) Biological cellular response to carbon nanoparticle toxicity. J Phys Condens Matter 18:S2185–S220110.1088/0953-8984/18/33/S34 ↗
17. Peters RH, De Bernardi R (1987) Daphnia. Consiglio nazionale delle recherché. Instituto italiano di, idrobiologia, Verbania Pallanza
18. Roberts AP, Mount AS, Seda B, Souther J, Qiao R, Lin S, Ke PC, Rao AM, Klaine SJ (2007) In vivo biomodification of lipid-coated carbon nanotubes by Daphnia magna. Environ Sci Technol 41(8):3025–302910.1021/es062572a ↗
19. Sayes CM, Fortner JD, Guo W, Lyon D, Boyd AM, Ausman KD, Tao YJ, Sitharaman B, Wilson LJ, Hughes JB, West JL, Colvin VL (2004) The differential cytotoxicity of water-soluble fullerenes. Nano Lett 4:1881–188710.1021/nl0489586 ↗
20. Sayes CM, Liang F, Hudson JL, Mendez J, Guo W, Jm Beach, Moore VC, Doyle DC, West JL, Billups WE, Ausman KD, Colvin VL (2006) Functionalization density dependence of single-walled carbon nanotubes cytotoxicity in vitro. Toxicol Lett 161:135–14210.1016/j.toxlet.2005.08.011 ↗
21. Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) (2005) The appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologie. http://ec.europa.eu/comm/health/ph_risk/committees/04_scenihr/04_scenihr_en.htm . Accessed 20 Mar 2006
22. Service RF (2000) Is nanotechnology dangerous? Science 290:1526–152710.1126/science.290.5496.1526 ↗
23. Service RF (2003) Nanomaterials show signs of toxicity. Science 300:243–24310.1126/science.300.5617.243a ↗
24. Smith CJ, Shaw BJ, Handy RD (2007) Toxicity of single walled carbon nanotubes to rainbow trout, (Oncorhynchus mykiss): respiratory toxicity, organ pathologies, and other physiological effects. Aquat Toxicol 82:94–10910.1016/j.aquatox.2007.02.003 ↗
25. Templeton R, Leeferguson P, Washburn K, Scrivens W, Thomaschandler G (2006) Life-cycle effects of single-walled carbon nanotubes (SWNTs) on an estuarine meiobenthic copepod. Environ Sci Technol 40(23):7387–739310.1021/es060407p ↗
26. Usenko CY, Harper SL, Tanguay RL (2007) In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish. Carbon 45:1891–189810.1016/j.carbon.2007.04.021 ↗
27. Zhu SQ, Oberdörster E, Haasch ML (2006) Toxicity of an engineered nanoparticle (fullerene, C60) in two aquatic species, Daphnia and fathead minnow. Mar Environ Res 62(Supplement 1):S5–S9
28. Zhu X, Zhu L, Li Y, Duan Z, Chen W, Alvarez PJJ (2007) Developmental toxicity in zebrafish embryos after exposure to manufactured nanomaterials: buckminsterfullerene aggregates (nC60) and fullerol. Environ Toxicol Chem 26(5):976–97910.1897/06-583.1 ↗
29. Zhu X, Zhu L, Li Y, Qi R, Duan Z, Lang YP (2008) Comparative toxicity of several metal oxide nano-particle aqueous suspensions to zebrafish (Danio rerio) early developmental stage. J Environ Sci Health A 43(3):278–28410.1080/10934520701792779 ↗