journal article·2021-09-01

Hydrogel prepared by 3D printing technology and its applications in the medical field

Cheng Liu, Na Xu, Qida Zong, Jia Yu, Peng Zhang

Publisher page

Abstract

Abstract As a cutting-edge technology, three-dimensional (3D) printing technology is currently widely used in many fields, and hydrogel as an emerging material is also more and more widely used. However, ordinary hydrogel has poor physical properties and relatively insufficient stability. The hydrogel based on 3D printing technology has been paid more and more attentions by researchers. 3D printing hydrogel combines the advantages of both 3D printing and hydrogel, and has excellent physical and chemical properties, such as high mechanical strength, excellent electrical conductivity. It has been made into many 3D complex structural scaffolds. Because the prepared complex structural scaffolds have good biocompatibility, biodegradability and other advantages, 3D printing hydrogel have been fully applied in the medical field. In this review, the preparation materials, physical and chemical properties, preparation methods of 3D printing hydrogel and its applications in the medical field are summarized systematically.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: 3D Printing in Biomedical Research · Additive Manufacturing and 3D Printing Technologies · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. 3D printing technologies: techniques, materials, and post-processing10.1016/j.coche.2020.04.001 ↗
2. 3D printing of polymer matrix composites: a review and prospective10.1016/j.compositesb.2016.11.034 ↗
3. Using 3D printing technology to teach cartilage framework carving for ear reconstruction10.3389/fsurg.2020.00044 ↗
4. Application of 3D printing technology in bone tissue engineering: a review
5. Engineering of brain-like tissue constructs via 3D cell-printing technology10.1088/1758-5090/ab7d76 ↗
6. On -demand fully customizable drug tablets via 3D printing technology for personalized medicine10.1016/j.jconrel.2020.02.046 ↗
7. Application of 3D printing technology for generating hollow-type suppository shells10.1016/j.ijpharm.2020.119825 ↗
8. Design and characterization of a novel 3D printed pressure-controlled drug delivery system10.1016/j.ejps.2019.105060 ↗
9. Preparation and characterization of polypills containing aspirin and simvastatin using 3D printing technology for the prevention of cardiovascular diseases10.1080/03639045.2020.1820034 ↗
10. A new era of water treatment technologies: 3D printing for membranes10.1016/j.jiec.2020.07.043 ↗
11. Applications of 3D printing technology to address COVID-19-related supply shortages10.1016/j.amjmed.2020.04.002 ↗
12. Recent progress on hydrogel actuators10.1039/D0TB02524K ↗
13. DNA materials: bridging nanotechnology and biotechnology10.1021/ar5001082 ↗
14. Preparation of intelligent DNA hydrogel and its applications in biosensing10.1016/j.eurpolymj.2020.109951 ↗
15. Progress on preparation of pH/temperature-sensitive intelligent hydrogels and applications in target transport and controlled release of drugs10.1155/2021/1340538 ↗
16. Intelligent-responsive hydrogels-based controlled drug release systems an its applications
17. Analyte-responsive hydrogels: intelligent materials for biosensing and drug delivery10.1021/acs.accounts.6b00533 ↗
18. Preparation and characterization of thermoresponsive poly(N-isopropylacrylamide-co-acrylicacid)-grafted hollow Fe3O4/SiO2 microspheres with surface holes for BSA release10.3390/ma10040411 ↗
19. Visible light-triggered on-demand drug release from hybrid hydrogels and its application in transdermal patches10.1002/adhm.201500323 ↗
20. Tunable thermo-responsive hydrogels: synthesis, structural analysis and drug release studies10.1016/j.msec.2014.12.045 ↗
21. A responsive porous hydrogel particle-based delivery system for oncotherapy10.1039/C8NR09990A ↗
22. PEG-PCL based micelle hydrogels as oral docetaxel delivery systems for breast cancer therapy10.1016/j.biomaterials.2014.04.099 ↗
23. Glucose-responsive hydrogel-based microneedles containing phenylborate ester bonds and N-isopropylacrylamide moieties and their transdermal drug delivery properties10.1016/j.eurpolymj.2021.110348 ↗
24. ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo10.1016/j.biomaterials.2019.119726 ↗
25. Preparation of novel nano-sized hydrogel microcapsules via layer-by-layer assembly as delivery vehicles for drugs onto hygiene paper10.3390/polym10030335 ↗
26. A nano-sized gel-in-oil suspension for transcutaneous protein delivery10.1016/j.ijpharm.2019.118495 ↗
27. A biological magnetic nano-hydrogel based on basil seed mucilage: study of swelling ratio and drug delivery10.1007/s13726-021-00905-0 ↗
28. NIR light-responsive short peptide/2D NbSe2 nanosheets composite hydrogel with controlled-release capacity10.1039/C8TB03326A ↗
29. Swelling behaviors of 3D printed hydrogel and hydrogel-microcarrier composite scaffolds10.1089/ten.tea.2020.0377 ↗
30. 3D printing of dual-physical cross-linking hydrogel with ultrahigh strength and toughness10.1021/acs.chemmater.0c02941 ↗
31. Recent progress in 3D printing of elastic and high-strength hydrogels for the treatment of osteochondral and cartilage diseases10.3389/fbioe.2020.604814 ↗
32. Humidity-responsive actuation of programmable hydrogel microstructures based on 3D printing10.1016/j.snb.2017.12.053 ↗
33. 3D-extrusion printing of stable constructs composed of photoresponsive polypeptide hydrogels10.1039/C9PY00796B ↗
34. Temperature-responsive methylcellulose-hyaluronic hydrogel as a 3D cell culture matrix10.1021/acs.biomac.0c00906 ↗
35. 3D printed stimuli-responsive magnetic nanoparticle embedded alginate-methylcellulose hydrogel actuators
36. Study on temperature and near-infrared driving characteristics of hydrogel actuator fabricated via molding and 3D printing10.1016/j.jmbbm.2017.11.043 ↗
37. Hierarchical chemomechanical encoding of multi-responsive hydrogel actuators via 3D printing10.1039/C9TA03547H ↗
38. 3D printing in pharmaceuticals: An emerging technology full of challenges10.1016/j.pharma.2020.08.007 ↗
39. Preparation of a photocurable hydrogel with adjustable mechanical properties for 3D printing10.1108/RPJ-03-2020-0053 ↗
40. Designing biomaterials for 3D printing10.1021/acsbiomaterials.6b00121 ↗
41. Preparation of cellulose nanofiber-reinforced gelatin hydrogel and optimization for 3D printing applications10.15376/biores.13.3.5909-5924 ↗
42. Effect of gelatin on dimensional stability of silk fibroin hydrogel structures fabricated by digital light processing 3D printing10.1016/j.jiec.2020.03.034 ↗
43. 3D-printed bioactive and biodegradable hydrogel scaffolds of alginate/gelatin/cellulose nanocrystals for tissue engineering10.1016/j.ijbiomac.2020.12.011 ↗
44. Study on 3D printing technology and mechanical properties of a nano-enhanced composite hydrogel bio-ink10.1049/mnl.2019.0712 ↗
45. 3D printed hydrogel-based sensors for quantifying UV exposure10.1021/acsami.0c12086 ↗
46. Electron beam crosslinking of alginate/nanoclay ink to improve functional properties of 3D printed hydrogel for removing heavy metal ions10.1016/j.carbpol.2020.116211 ↗
47. Preparation of multi-scale hydrogel scaffolds for tissue engineering through biologic hydrogel 3D printing and forming system10.1166/jbt.2018.1861 ↗
48. 3D printing of high-strength chitosan hydrogel scaffolds without any organic solvents10.1039/D0BM00896F ↗
49. 3D printing of silk particle-reinforced chitosan hydrogel structures and their properties10.1021/acsbiomaterials.8b00804 ↗
50. An injectable, self-healing phenol-functionalized chitosan hydrogel with fast gelling property and visible light-crosslinking capability for 3D printing10.1016/j.actbio.2020.12.051 ↗
51. 3D printing of a reactive hydrogel bio-ink using a static mixing tool10.3390/polym12091986 ↗
52. Direct 3D printed biomimetic scaffolds based on hydrogel microparticles for cell spheroid growth10.1002/adfm.201910573 ↗
53. Snakegourd root/Astragalus polysaccharide hydrogel preparation and application in 3D printing10.1016/j.ijbiomac.2018.10.008 ↗
54. Fabrication of multiple-layered hydrogel scaffolds with elaborate structure and good mechanical properties via 3D printing and ionic reinforcement10.1021/acsami.8b04116 ↗
55. Micro 3D printing of a temperature-responsive hydrogel using projection micro-stereolithography10.1038/s41598-018-20385-2 ↗
56. Fabrication of photothermally responsive nanocomposite hydrogel through 3D printing10.1002/mame.201900718 ↗
57. Self-crosslinking hyaluronic acid-carboxymethylcellulose hydrogel enhances multilayered 3D-printed construct shape integrity and mechanical stability for soft tissue engineering10.1088/1758-5090/aba2f7 ↗
58. A mechanically enhanced electroactive hydrogel for 3D printing using a multileg long chain crosslinker10.1088/1361-665X/ab325d ↗
59. Lyophilized scaffolds fabricated from 3D-printed photocurable natural hydrogel for cartilage regeneration10.1021/acsami.8b10926 ↗
60. Creating complex polyacrylamide hydrogel structures using 3D printing with applications to mechanobiology10.1002/mabi.202000082 ↗
61. Ultrastretchable and self-healing double-network hydrogel for 3D printing and strain sensor10.1021/acsami.7b07445 ↗
62. An overview of the suitability of hydrogel-forming polymers for extrusion-based 3D-printing10.1039/C5TB00393H ↗
63. 3D printing hydrogel-based soft and biohybrid actuators: a mini-review on fabrication techniques10.3389/frobt.2021.673533 ↗
64. Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels10.1126/sciadv.1500758 ↗
65. Recent trends in bioinks for 3D printing10.1186/s40824-018-0122-1 ↗
66. Extrusion-based 3D printing of microfluidic devices for chemical and biomedical applications: a topical review10.3390/mi9080374 ↗
67. 3D printing in personalized drug delivery: An overview of hot-melt extrusion-based fused deposition modeling10.1016/j.ijpharm.2021.120501 ↗
68. Bioink properties before, during and after 3D bioprinting
69. Development and quantitative characterization of the precursor rheology of hyaluronic acid hydrogels for bioprinting10.1016/j.actbio.2019.01.041 ↗
70. Current status of three-dimensional printing inks for soft tissue regeneration10.1007/s13770-016-0125-8 ↗
71. Evolution of bioinks and additive manufacturing technologies for 3D bioprinting10.1021/acsbiomaterials.6b00088 ↗
72. A 3D printed chitosan-pectin hydrogel wound dressing for lidocaine hydrochloride delivery10.1016/j.msec.2019.109873 ↗
73. 3D printing of a poly(vinyl alcohol)-based nano-composite hydrogel as an artificial cartilage replacement and the improvement mechanism of printing accuracy10.1039/C9TB02278C ↗
74. 3D printing of tough hydrogel composites with spatially varying materials properties
75. 4D printing with mechanically robust, thermally actuating hydrogels10.1002/marc.201500079 ↗
76. Three-dimensional photopatterning of hydrogels using stereolithography for long-term cell encapsulation10.1039/c004285d ↗
77. Femtosecond laser induced densification within cell-laden hydrogels results in cellular alignment10.1088/1758-5090/ab0f8b ↗
78. A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering10.1016/j.biomaterials.2012.04.050 ↗
79. Development of micro-stereolithography technology using a UV lamp and optical fiber10.1007/s00170-008-1461-1 ↗
80. Novel materials for 3D printing by photopolymerization10.1002/adma.201706344 ↗
81. Living additive manufacturing: transformation of parent gels into diversely functionalized daughter gels made possible by visible light photoredox catalysis10.1021/acscentsci.6b00335 ↗
82. High-efficiency high-resolution multimaterial fabrication for digital light processing-based three-dimensional printing10.1089/3dp.2018.0004 ↗
83. Ultrafast three-dimensional printing of optically smooth microlens arrays by oscillation-assisted digital light processing10.1021/acsami.9b14692 ↗
84. 3D printing of highly stretchable hydrogel with diverse UV curable polymers10.1126/sciadv.aba4261 ↗
85. High-resolution 3D printing of stretchable hydrogel structures using optical projection lithography10.1021/acsami.9b19431 ↗
86. Hybrid laser printing of 3D, multiscale, multimaterial hydrogel structures10.1002/adom.201900656 ↗
87. Development of 3D printable conductive hydrogel with crystallized PEDOT:PSS for neural tissue engineering10.1016/j.msec.2019.02.008 ↗
88. Microdrop printing of hydrogel bioinks into 3D tissue-like geometries10.1002/adma.201102800 ↗
89. Three-dimensional inkjet biofabrication based on designed images10.1088/1758-5082/3/3/034113 ↗
90. Enabling free-standing 3D hydrogel microstructures with microreactive inkjet printing10.1021/acsami.9b17192 ↗
91. Polymers for 3D printing and customized additive manufacturing10.1021/acs.chemrev.7b00074 ↗
92. Recent progress of direct ink writing of electronic components for advanced wearable devices10.1021/acsaelm.9b00428 ↗
93. A new 3D printing strategy by harnessing deformation, instability, and fracture of viscoelastic inks10.1002/adma.201704028 ↗
94. Direct ink writing of mineral materials: a review10.1007/s40684-020-00222-6 ↗
95. Direct ink writing of materials for electronics-related applications: a mini review10.3389/fmats.2021.647229 ↗
96. Tough and conductive polymer hydrogel based on double network for photo-curing 3D printing10.1088/2053-1591/ab8cfb ↗
97. 3D printed ultrastretchable, hyper-antifreezing conductive hydrogel for sensitive motion and electrophysiological signal monitoring
98. Excretion and toxicity of gold-iron nanoparticles10.1016/j.nano.2012.08.007 ↗
99. Toxicity of gold nanoparticles (AuNPs): a review
100. A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks10.1080/10408440600570233 ↗