Multi-metal ions doped hydroxyapatite coatings via electrochemical methods for antibacterial and osteogenesis
Source abstract
Abstract
Abstract The Hydroxyapatite (HA) coating on the surface of titanium (Ti) with good bioactivity for osseointegration ability, however, the lack of antibacterial properties. In this study, the pulse electrochemical method was used to oxidize and polymerize pyrrole (Py) into polypyrrole (PPy) in situ, and PPy was used as the regulator of HA nanoparticles (HA-NPs) and metal particles to construct uniform PPy@HA/ZnO-Cu, PPy@HA/ZnO-Ag, PPy@HA/Ag-Cu, and PPy@HA/ZnO-Ag-Cu nanocomposite coatings on the Ti substrate. The antibacterial rates of four groups of composite coatings against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) were all 100%. The PPy@HA/ZnO-Ag composite coating could promote the growth and proliferation of Vascular Endothelial Cells (VECs) and Bone Marrow Mesenchymal Stem Cells (BMSCs). Therefore, the PPy@HA/ZnO-Ag composite coating has the best osteoinductive ability among all the groups, excellent antibacterial property, angiogenic and osteogenic capability, which can be used as an ideal implant coating.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Titanium Alloys Microstructure and Properties · Extraction and Separation Processes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (60)
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