Hydroxyapatite Biomineralization on Functionalized Silicone Nanofilaments
Source abstract
Abstract
In pursuit of designing novel biocompatible scaffold for hydroxyapatite (HA) growth, silicone nanofilaments coated surfaces have been investigated. High surface area of these 1-D nanofilaments offers large density of nucleation sites for biomineralization. The study shows that the amine and carboxylic acid functionalized SNFs enhance mineralization of HA particles whereas monolayer modified glass substrate did not show HA nucleation during the same period of time. Further investigation demonstrated the growth kinetics of HA particles and revealed that a dense and uniform coating of HA could be achieved after 7 days of immersion in simulated body fluid (SBF). This fast and facile approach could open up a new avenue for bone mineralization.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Calcium Carbonate Crystallization and Inhibition · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (25)
Show source-provided references
1. Functionalized synthetic biodegradable polymer scaffolds for tissue engineering10.1002/mabi.201100466 ↗
2. Crystalline hydroxyapatite coatings synthesized under hydrothermal conditions on modified titanium substrates10.1016/j.msec.2015.02.029 ↗
3. Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function10.1016/S0142-9612(99)00181-7 ↗
4. Biomimetic growth and substrate dependent mechanical properties of bone like apatite nucleated on Ti and magnetron sputtered TiO2 nanostructure10.1088/0022-3727/49/14/145304 ↗
5. Growth of hydroxyapatite coatings on biodegradable polymer microspheres10.1021/am9001716 ↗
6. Evaluation and characterization of nanostructure hydroxyapatite powder prepared by simple sol–gel method10.1016/j.matlet.2007.01.028 ↗
7. Electrochemical processes of nucleation and growth of hydroxyapatite on titanium supported by real-time electrochemical atomic force microscopy10.1002/jbm.a.30944 ↗
8. Electrophoretic deposition of porous hydroxyapatite scaffold10.1016/S0142-9612(03)00203-5 ↗
9. Pulsed laser deposition of hydroxyapatite thin films10.1016/j.msec.2006.05.025 ↗
10. Material fundamentals and clinical performance of plasma-sprayed hydroxyapatite coatings: a review10.1002/jbm.1056 ↗
11. In vitro studies of plasma-sprayed hydroxyapatite/Ti-6Al-4V composite coatings in simulated body fluid (SBF)10.1016/S0142-9612(02)00573-2 ↗
12. Biomimetic synthesis of enamel-like hydroxyapatite on self-assembled monolayers10.1016/j.msec.2006.08.002 ↗
13. How useful is SBF in predicting in vivo bone bioactivity?10.1016/j.biomaterials.2006.01.017 ↗
14. The role of surface functional groups in calcium phosphate nucleation on titanium foil: a self-assembled monolayer technique10.1016/S0142-9612(02)00050-9 ↗
15. Growth of hydroxyapatite in a biocompatible mesoporous ordered silica10.1016/j.actbio.2005.12.006 ↗
16. Simultaneous reduction and surface functionalization of graphene oxide for hydroxyapatite mineralization10.1021/jp2102226 ↗
17. Silicone nanofilaments and their application as superhydrophobic coatings10.1002/adma.200502030 ↗
18. Polyester materials with superwetting silicone nanofilaments for oil/water separation and selective oil absorption10.1002/adfm.201101090 ↗
19. Photocatalytic composites of silicone nanofilaments and TiO2 nanoparticles10.1002/adfm.201200816 ↗
20. Oil/water separation with selective superantiwetting/superwetting surface materials10.1002/anie.201405785 ↗
21. Functionalized silicone nanofilaments: a novel material for selective protein enrichment10.1021/la702977v ↗
22. Functionalization of self-assembled monolayers on glass and oxidized silicon wafers by surface reactions10.1002/poc.372 ↗
23. Nucleation and growth of hydroxyapatite on an amino organosilane overlayer10.1002/jbm.1245 ↗
24. Biomimetic and cell-mediated mineralization of hydroxyapatite by carrageenan functionalized graphene oxide10.1021/am4057826 ↗
25. Hydroxyapatite formation on sol–gel derived poly(ε-caprolactone)/bioactive glass hybrid biomaterials10.1021/am300487c ↗