journal article·2020-04Open access

Mitochondria‐Targeted Water‐Soluble Organic Nanoparticles of Chlorin Derivatives for Biocompatible Photodynamic Therapy

Yang Liu, Tae Heon Lee, Sang Hyeob Lee, Jiazhu Li, Woo Kyoung Lee, Il Yoon

ChemNanoMat· Volume 6· Issue 4

Abstract

Water-soluble organic nanoparticles (WSONs) were prepared by a very simple co-precipitation method through nanoprecipitation (solvent-exchange) from THF to water. WSONs are 87–112 nm in size with good water solubility and high water stability for more than a month. WSONs accumulated in mitochondria and induced mitochondria-mediated apoptosis through photodynamic activity against HeLa cells. More information can be found in the Full Paper by Woo Kyoung Lee, Il Yoon et al.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Porphyrin and Phthalocyanine Chemistry

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Center for Nano Manufacturing and Department of Nanoscience and Engineering Inje University 197 Injero, Gimhae Gyeongnam 50834 Republic of Korea

College of Chemistry and Chemical Engineering Yantai University Yantai 264005 China

References

Reference metadata was not supplied for this record.